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The application of tribology in assessing texture perception of oral liquid medicine





The palatability of medicines is likely to have a significant impact on patient adherence and consequently, on the safety and efficacy of a medicinal product. Palatability encompasses properties of medicines not limited to taste including swallowability (e.g. size, shape, texture). However, there has been limited work undertaken to measure the texture of medicines and how this may affect palatability and subsequent adherence.

Tribology offers an understanding of oral processes and can allow physical properties of materials to be linked to “mouthfeel”. This paper describes a preliminary application of tribology to oral liquid medicines and demonstrates that this technique is useful in the development of future oral liquid medicines.

Acceptance Date Jan 4, 2015
Publication Date Jan 6, 2015
Journal International Journal of Pharmaceutics
Print ISSN 0378-5173
Publisher Elsevier
Pages 277 - 281
Keywords tribology; texture; mouthfeel; medicine
Publisher URL