Thieme Chemistry Journal Awardees - Where are They Now? Synthesis of the Marine Glycolipid Dioctadecanoyl Discoside

Miller

Abstract

The first synthesis of the inositol-containing marine glycolipid dioctadecanoyl discoside is reported. The key glycosylation reaction proceeds with ß-selectivity at reduced temperature. The separable anomers could be readily progressed to afford discoside, its peracetate and the unnatural ß-derivatives.

Citation

Miller. (2009). Thieme Chemistry Journal Awardees - Where are They Now? Synthesis of the Marine Glycolipid Dioctadecanoyl Discoside. SYNLETT, 3099 -3102. https://doi.org/10.1055/s-0029-1218301

• Acceptance Date: Oct 21, 2009
• Publication Date: Dec 1, 2009
• Journal: Synlett
• Print ISSN: 0936-5214
• Publisher: Thieme Gruppe
• Pages: 3099 -3102
• DOI: https://doi.org/10.1055/s-0029-1218301
• Keywords: marine sponge, glycolipid, mannose, glycosylation, inositol
• Publisher URL: http://dx.doi.org/10.1055/s-0029-1218301