Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols

Peat, George; Riley, Richard D.; Croft, Peter; Morley, Katherine I.; Kyzas, Panayiotis A.; Moons, Karel G.M.; Perel, Pablo; Steyerberg, Ewout W.; Schroter, Sara; Altman, Douglas G.; Hemingway, Harry; van der Windt, Danielle

doi:10.1371/journal.pmed.1001671

Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols

Peat, George; Riley, Richard D.; Croft, Peter; Morley, Katherine I.; Kyzas, Panayiotis A.; Moons, Karel G.M.; Perel, Pablo; Steyerberg, Ewout W.; Schroter, Sara; Altman, Douglas G.; Hemingway, Harry; van der Windt, Danielle

Authors

George Peat

Richard D. Riley

Peter Croft

Katherine I. Morley

Panayiotis A. Kyzas

Karel G.M. Moons

Pablo Perel

Ewout W. Steyerberg

Sara Schroter

Douglas G. Altman

Harry Hemingway

Danielle Van Der Windt d.van.der.windt@keele.ac.uk

Abstract

Prognosis research is concerned with predicting outcomes to make health care more effective. It has a crucial role to play in clinical and policy decision-making. The quality of much prognosis research is poor, evidenced by incomplete reporting, poor data sharing, incomplete registrations, and absent study protocols. Initiatives to improve transparency in trials include reporting guidelines, data pooling, registers, and journal requirements for protocols. Prognosis research could be transformed by similar initiatives. Routine registration of all prognostic studies, linked to an accessible study protocol using agreed reporting guidelines, would improve transparency and promote data sharing. Concern about applying transparency methods to observational research could be resolved by flexibility to update date-stamped protocols during prognosis studies.

Citation

Peat, G., Riley, R. D., Croft, P., Morley, K. I., Kyzas, P. A., Moons, K. G., Perel, P., Steyerberg, E. W., Schroter, S., Altman, D. G., Hemingway, H., & van der Windt, D. (2014). Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols. PLoS Medicine, e1001671 -?. https://doi.org/10.1371/journal.pmed.1001671

Journal Article Type	Article
Acceptance Date	Jul 8, 2014
Publication Date	Jul 8, 2014
Journal	PLoS Medicine
Print ISSN	1549-1277
Electronic ISSN	1549-1676
Publisher	Public Library of Science (PLoS)
Pages	e1001671 -?
DOI	https://doi.org/10.1371/journal.pmed.1001671
Keywords	biomedical research, clinical protocols, humans, information dissemination, prognosis, vital statistics
Public URL	https://keele-repository.worktribe.com/output/408182
Publisher URL	http://dx.doi.org/10.1371/journal.pmed.1001671