Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugate

Hawes, Chris S.

Abstract

The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases (TB-1-TB-3) and a new Tröger's base p-cymene-Ru(ii)-curcumin organometallic conjugate (TB-Ru-Cur) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.

Citation

Hawes, C. S. (2018). Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugate. Chemical Communications, 4120-4123. https://doi.org/10.1039/C8CC01584H

• Acceptance Date: Mar 29, 2018
• Publication Date: Apr 6, 2018
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Publisher: Royal Society of Chemistry
• Pages: 4120-4123
• DOI: https://doi.org/10.1039/C8CC01584H
• Keywords: materials chemistry, electronic, optical and magnetic materials, general chemistry,surfaces, coatings and films, metals and alloys, ceramics and composites, catalysis
• Publisher URL: http://dx.doi.org/10.1039/C8CC01584H