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Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts

Shoaib, Ahmad; Kinnaird, Tim; Curzen, Nick; Kontopantelis, Evangelos; Ludman, Peter; de Belder, Mark; Rashid, Muhammad; Shing Kwok, Chun; Nolan, James; Zaman, Azfar; Mamas, Mamas


Ahmad Shoaib

Tim Kinnaird

Nick Curzen

Evangelos Kontopantelis

Peter Ludman

Mark de Belder

Muhammad Rashid

Chun Shing Kwok

Azfar Zaman


Background: There are limited data on outcomes of patients with previous CABG presenting with NSTEMI undergoing PCI. We compare clinical characteristics and outcomes in NSTEMI patients undergoing PCI with or without prior CABG surgery in a national cohort. Methods & Results: We identified 205,039 patients with NSTEMI who underwent PCI between 2007-2014 in the British Cardiovascular Intervention Society (BCIS) database. Clinical, demographical, procedural and outcome data were analysed by dividing into three groups; Group 1- PCI in native coronary arteries and no prior CABG (n= 186,670), Group 2- PCI in native arteries with prior CABG (n= 8,825), Group 3- PCI in Grafts (n= 9,544). Patients in Group 2 & 3 were older, had more comorbidities and higher mortality at 30 days (group 2 -2.6%, group 3 – 1.9%) and 1 year (group 2 – 8.29%, group 3 – 7.08%) as compared to Group 1 (1.7% & 4.87%). Following multivariable analysis, no significant difference in outcomes were observed in 30 days mortality (OR: group 2 = 0.87 (CI 0.69-1.80, P-0.20), group 3 = 0.91 (CI 0.71-1.17, P-0.46)), in-hospital MACE (OR: group 2 = 1.08 (CI 0.88-1.34, P- 0.45), group 3 0.97 (CI 0.77-1.23, P- 0.82)) and in-hospital stroke (OR: group 2 = 1.37 (CI 0.71-2.69, P - 0.35), group 3 = 1.13 (CI 0.55-2.34, P- 0.73))(group 1= reference). Conclusion: Patients with prior CABG presenting with NSTEMI and treated with PCI had more co-morbid illnesses but once these differences were adjusted for, prior CABG did not independently confer additional risk of mortality and MACE. Keywords: PCI, NSTEMI, Mortality, Complications

Journal Article Type Article
Acceptance Date Sep 13, 2018
Publication Date Nov 16, 2018
Journal Circulation: Cardiovascular Interventions
Print ISSN 1941-7640
Publisher American Heart Association
Peer Reviewed Peer Reviewed
Volume 11
Issue 11
Keywords comorbidity; coronary artery disease; mortality; myocardial infarction; percutaneous coronary intervention
Publisher URL