Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid

Beswick, Laura; Ahmadipour, Sanaz; Dolan, Jonathan P.; Rejzek, Martin; Field, Robert A.; Miller, Gavin J.

Abstract

Highlights

Sugarnucleotide synthesis.

Chemical and enzymatic access to GDP-d-ManA.

Evaluation of protected and free uronate 1-phosphates for pyrophosphorylation.

Citation

Beswick, L., Ahmadipour, S., Dolan, J. P., Rejzek, M., Field, R. A., & Miller, G. J. (2019). Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid. Carbohydrate Research, 485(1), 107819 -107819. https://doi.org/10.1016/j.carres.2019.107819

• Journal Article Type: Article
• Acceptance Date: Sep 16, 2019
• Online Publication Date: Sep 17, 2019
• Publication Date: Nov 1, 2019
• Publicly Available Date: May 26, 2023
• Journal: Carbohydrate Research
• Print ISSN: 0008-6215
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 485
• Issue: 1
• Pages: 107819 -107819
• DOI: https://doi.org/10.1016/j.carres.2019.107819
• Keywords: Sugar nucleotide; Glycosyl-1-phosphate; Mannuronate; Pyrophosphorylation; Alginate
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0008621519304458