Urate Lowering for Blood Pressure Control in Adults: Another Nail in the Coffin?

Roddy, Edward

Abstract

Numerous observational studies have reported an association between serum urate and elevated blood pressure in adult populations (1). These observations, together with experimental in vivo studies, have generated substantial interest in the role of hyperuricaemia as a mediator of elevated blood pressure, with various postulated mechanisms, including activation of renin-angiotensin system, oxidative stress, reduced endothelial nitric oxide availability, and renal vasoconstriction (2).

Citation

Roddy, E., & Dalbeth, N. (2021). Urate Lowering for Blood Pressure Control in Adults: Another Nail in the Coffin?. Arthritis and Rheumatology, 73(8), 1408-1411. https://doi.org/10.1002/art.41751

• Journal Article Type: Article
• Acceptance Date: Mar 25, 2021
• Online Publication Date: Jun 8, 2021
• Publication Date: 2021-08
• Publicly Available Date: May 30, 2023
• Journal: Arthritis & Rheumatology
• Print ISSN: 2326-5191
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 73
• Issue: 8
• Pages: 1408-1411
• DOI: https://doi.org/10.1002/art.41751
• Keywords: Immunology, Rheumatology, Immunology and Allergy
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1002/art.41751