A Inskip
Identification of polymorphism at the glutathione s-transferase, GSTM3 locus: Evidence for linkage with GSTMI*A
Inskip, A; Elexperu-Camiruaga, J; Buxton, N; Dias, P S; MacIntosh, J; Campbell, D; Jones, P W; Yengi, L; Talbot, J A; Strange, R C; Fryer, A A
Authors
J Elexperu-Camiruaga
N Buxton
P S Dias
J MacIntosh
D Campbell
P W Jones
L Yengi
J A Talbot
R C Strange
A A Fryer
Contributors
A. Inskip
Other
J. Elexperu-Camiruaga
Other
N. Buxton
Other
P.S. Dias
Other
J. Maclntosh
Other
D. Campbell
Other
P.W. Jones
Other
L. Yengi
Other
J.A. Talbot
Other
R.C. Strange
Other
A.A. Fryer
Other
Abstract
Allelism in the glutathione S-transferase, GSTM3 gene has been identified using PCR with specific primers to exon 6/exon 7. Sequencing showed the mutant GSTM3*B allele to have a three-base deletion in intron 6 with a frequency of 0.158. The mutation generates a recognition sequence, 5′-AAGATA-3′, for the negative transcription factor YY1. GSTM3*B was significantly associated with GSTM1*A.
Citation
Inskip, A., Elexperu-Camiruaga, J., Buxton, N., Dias, P. S., MacIntosh, J., Campbell, D., Jones, P. W., Yengi, L., Talbot, J. A., Strange, R. C., & Fryer, A. A. (1995). Identification of polymorphism at the glutathione s-transferase, GSTM3 locus: Evidence for linkage with GSTMI*A. Biochemical Journal, 312(3), 713–716. https://doi.org/10.1042/bj3120713
| Journal Article Type | Article |
|---|---|
| Publication Date | 1995-12 |
| Deposit Date | Feb 14, 2024 |
| Journal | Biochemical Journal |
| Print ISSN | 0264-6021 |
| Electronic ISSN | 1470-8728 |
| Publisher | Portland Press |
| Peer Reviewed | Peer Reviewed |
| Volume | 312 |
| Issue | 3 |
| Pages | 713–716 |
| DOI | https://doi.org/10.1042/bj3120713 |
| Public URL | https://keele-repository.worktribe.com/output/622376 |
| Publisher URL | https://portlandpress.com/biochemj/article-abstract/312/3/713/38051/Identification-of-polymorphism-at-the-glutathione?redirectedFrom=fulltext |