A scoping review of patient self-report measures of flare in knee and hip osteoarthritis (OA): A report from the OMERACT flares in OA working group

Queiroga, Fabiana; Cross, Marita; Thomas, Martin J.; March, Lyn; Epstein, Jonathan; Guillemin, Francis

Abstract

Purpose
We aimed to analyze the content validity/domain match and feasibility of self-report instruments that could measure flare in osteoarthritis (OA), by extending our 2017 literature review on the definition of flare in knee and hip OA.

Method
We searched PubMed (Medline), Web of Science and PsycInfo (Ebsco Host) databases for original articles reporting research about flare (or synonyms) in humans with knee and hip OA, between 2017 and 2023. Four experts worked independently, checking the records, and assessing content validity and feasibility, writing justification for exclusion.

Results
At literature review phase, 575 papers were filtered. After experts’ analysis, 59 studies were included, and 44 instruments associated with flare in OA were identified. Most were studies about pain in knee or hip OA (35 %), cultural adaptation of a measure (33 %) or studies investigating psychometric properties of full (16 %) or short form (4 %) instruments. The assessment of domain match and feasibility revealed that 15 instruments were assigned a label of ‘yes’ or ‘uncertain’ as to whether or not there was a good match with the domain concept or whether the instrument was considered feasible to use.

Discussion
Most identified instruments considered different aspects of pain and the associated discomfort in performing daily activities but did not include the central aspects of flare in OA, i.e. the change of state, nor the additional Outcome Measures in Rheumatology (OMERACT) endorsed domains for OA flare namely stiffness, swelling, psychological aspects, impact of symptoms including fatigue and sleep disturbance. Although it is possible that the period specified to conduct this literature review may have led to some recognized instruments being excluded, this review demonstrates the need for the research community to reach consensus on the best way to measure self-reported flares in future clinical trials and observational studies.

Citation

Queiroga, F., Cross, M., Thomas, M. J., March, L., Epstein, J., & Guillemin, F. (2023). A scoping review of patient self-report measures of flare in knee and hip osteoarthritis (OA): A report from the OMERACT flares in OA working group. Seminars in Arthritis and Rheumatism, 63, Article 152281. https://doi.org/10.1016/j.semarthrit.2023.152281

• Journal Article Type: Article
• Acceptance Date: Oct 12, 2023
• Online Publication Date: Oct 14, 2023
• Publication Date: 2023-12
• Deposit Date: Dec 7, 2023
• Publicly Available Date: Oct 15, 2024
• Journal: Seminars in Arthritis and Rheumatism
• Print ISSN: 0049-0172
• Electronic ISSN: 1532-866X
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 63
• Article Number: 152281
• DOI: https://doi.org/10.1016/j.semarthrit.2023.152281
• Keywords: Knee and hip osteoarthritis; Self-report measures; Patient's perspective; OMERACT; Flare in OA
• Additional Information: This article is maintained by: Elsevier; Article Title: A scoping review of patient self-report measures of flare in knee and hip osteoarthritis (OA): A report from the OMERACT flares in OA working group; Journal Title: Seminars in Arthritis and Rheumatism; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.semarthrit.2023.152281; Content Type: article; Copyright: © 2023 Elsevier Inc. All rights reserved.