OP0194-HPR Clinical outcomes of nurse-led care for people with RA: A multicentre RCT:

Ndosi, M.; Lewis, M.; Hale, C.; Bird, H.; Ryan, S.; Quinn, H.; McIvor, L.; Taylor, J.; Burbage, G.; Bond, D.; White, J.; Chagadama, D.; Green, S.; Kay, L.; Pace, A.V.; Bejarano, V.; Emery, P.; Hill, J.

Abstract

Background Despite the development of the innovative rheumatology nurse-led clinics (NLC) in the UK, the evidence of their effectiveness is limited.

Objectives To compare the outcomes of NLC to those obtained by rheumatologist-led clinics (RLC) for people with RA. The null hypothesis tested is that NLC is inferior to RLC.

Methods This was a multi-centred, non-inferiority RCT. The non-inferiority margin was DAS28 change of 0.6 from baseline (primary outcome) and standardised effect size for secondary outcomes (pain, fatigue, stiffness, RAQoL, HAQ, HAD, ASES and EQ5D-VAS). Patients were assessed at baseline and at weeks 13, 26, 39 & 52. Mean differences between the two groups at follow-up were estimated using linear mixed models controlling for age, gender, centre, baseline DAS28 and corresponding baseline values for secondary outcomes. This was done following per-protocol (PP) and Intention-to-treat (ITT) strategies. Level of patient satisfaction was also compared between groups.

Results Patients under NLC (n=91) were comparable to those under RLC (n=90) in their demographic and baseline characteristics. Their mean (SD) age was 58.5 (11.6); disease duration 9.9 (10.7) years and 74% were female.

Citation

Ndosi, M., Lewis, M., Hale, C., Bird, H., Ryan, S., Quinn, H., McIvor, L., Taylor, J., Burbage, G., Bond, D., White, J., Chagadama, D., Green, S., Kay, L., Pace, A., Bejarano, V., Emery, P., & Hill, J. OP0194-HPR Clinical outcomes of nurse-led care for people with RA: A multicentre RCT:. Presented at Annual European Congress of Rheumatology EULAR (6–9 June 2012), Berlin, Germany

• Presentation Conference Type: Conference Abstract
• Conference Name: Annual European Congress of Rheumatology EULAR (6–9 June 2012)
• Online Publication Date: Jan 23, 2014
• Publication Date: 2013-06
• Deposit Date: Nov 30, 2023
• Journal: Annals of the Rheumatic Diseases
• Print ISSN: 0003-4967
• Electronic ISSN: 1468-2060
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 71
• Issue: Suppl 3
• Pages: 120.2-120
• DOI: https://doi.org/10.1136/annrheumdis-2012-eular.1877
• Keywords: General Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology
• Public URL: https://keele-repository.worktribe.com/output/653816