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All Outputs (126)

Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial (2018)
Journal Article
Kigozi, J., Jowett, S., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., …Mallen, C. D. (2018). Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial. Arthritis Care and Research, 70(12), 1787-1794. https://doi.org/10.1002/acr.23568

OBJECTIVE: To investigate the cost-effectiveness (cost-utility) of introducing general practitioner screening for anxiety and depression in patients consulting with osteoarthritis (OA). METHODS: A cluster-randomised trial-based economic evaluation to... Read More about Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.

Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis (2018)
Journal Article
Oppong, R., Jowett, S., Lewis, M., Clarkson, K., Paskins, Z., Croft, P., …Dziedzic, K. (2018). Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis. Rheumatology, 57(6), 1056-1063. https://doi.org/10.1093/rheumatology/key037

Objectives: The aim of this study was to estimate the cost-effectiveness of a model OA consultation for OA to support self-management compared with usual care. Methods: An incremental cost-utility analysis using patient responses to the three-level E... Read More about Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis.

Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials. (2018)
Journal Article
Green, D., Lewis, M., Mansell, G., Artus, M., Dziedzic, K., Hay, E., …Van Der Windt, D. (2018). Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials. European Journal of Pain, 22(6), 1057-1070. https://doi.org/10.1002/ejp.1190

BACKGROUND: Previous research has identified similar prognostic factors in patients with musculoskeletal (MSK) conditions regardless of pain presentation, generating opportunities for management based on prognosis rather than specific pain presentati... Read More about Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials..

The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. (2018)
Journal Article
Healey, E., Herron, D., Hider, S., Bucknall, M., Cooke, K., Finney, A., …Chew-Graham, C. (2018). The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. Journal of Comorbidity, 8(1), https://doi.org/10.1177/2235042X18792373

Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and dep... Read More about The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial..

Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669). (2018)
Journal Article
Wynne-Jones, G., Artus, M., Bishop, A., Lawton, S., Lewis, M., Jowett, S., …Van Der Windt, D. (2018). Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669). PAIN, 159(1), 128-138. https://doi.org/10.1097/j.pain.0000000000001075

Musculoskeletal pain is a common cause of work absence and early intervention is advocated to prevent the adverse health and economic consequences of longer-term absence. This cluster randomised controlled trial investigated the effect of introducing... Read More about Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669)..

Multisite peripheral joint pain: a cross-sectional study of prevalence and impact on general health, quality of life, pain intensity and consultation behaviour (2017)
Journal Article
Finney, A., Dziedzic, K., Lewis, A., & Healey, E. (2017). Multisite peripheral joint pain: a cross-sectional study of prevalence and impact on general health, quality of life, pain intensity and consultation behaviour. BMC Musculoskeletal Disorders, 18, Article 535. https://doi.org/10.1186/s12891-017-1896-3

Background Research into musculoskeletal conditions often focusses on pain at single sites, such as the knee, yet several studies have previously reported the high prevalence of multiple sites of musculoskeletal pain. The most common form of musculo... Read More about Multisite peripheral joint pain: a cross-sectional study of prevalence and impact on general health, quality of life, pain intensity and consultation behaviour.

The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol (2017)
Journal Article
Healey, E., Jinks, C., Foster, N., Chew-Graham, Chew-Graham, C., Pincus, T., …McBeth, J. (2017). The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol. Musculoskeletal Care, 16(1), https://doi.org/10.1002/msc.1222

INTRODUCTION: This pilot trial will inform the design and methods of a future full-scale randomized controlled trial (RCT) and examine the feasibility, acceptability and fidelity of the Increasing Physical activity in Older People with chronic Pain (... Read More about The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). (2017)
Journal Article
Barnett, L., Mallen, C., Lewis, A., & Peat, G. (2017). Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). Trials, 18, 585 - ?. https://doi.org/10.1186/s13063-017-2329-1

BACKGROUND: Selection bias is a concern when designing cluster randomised controlled trials (c-RCT). Despite addressing potential issues at the design stage, bias cannot always be eradicated from a trial design. The application of bias analysis prese... Read More about Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST)..

Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort (2017)
Journal Article
Konstantinou, K., Dunn, K., Ogollah, R., Lewis, M., Van Der Windt, D., Hay, E., & Study Team, A. (2017). Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort. Spine Journal, 1030-1040. https://doi.org/10.1016/j.spinee.2017.10.071

Background Context Evidence is lacking on the prognosis and prognostic factors of back-related leg pain and sciatica in patients seeing their primary care physicians. This evidence could guide timely appropriate treatment and referral decisions.... Read More about Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.

Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial (2017)
Journal Article
Dziedzic, K., Hay, E., Porcheret, M., Afolabi, E., Lewis, A., Morden, A., …Healey, E. (2018). Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial. Osteoarthritis and Cartilage, 26(1), 43-53. https://doi.org/10.1016/j.joca.2017.09.010

Objective To determine the effectiveness of a model osteoarthritis consultation, compared with usual care, on physical function and uptake of National Institute for Health and Care Excellence (NICE) osteoarthritis recommendations, in adults =45 year... Read More about Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial.

Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial (2017)
Journal Article
Jinks, C., Nicholls, E., Liddle, J., Healey, E., Evans, A., Chew-Graham, C., …Team, E. (2017). Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial. Annals of the Rheumatic Diseases, 76(S2), 1433-1433. https://doi.org/10.1136/annrheumdis-2017-eular.2473

Background Co-morbid osteoarthritis (OA), anxiety and depression are undermanaged in primary care yet have significant impact on pain, disability and outcomes of other long-term conditions (LTCs). Objectives To test the feasibility and acceptabili... Read More about Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial.

The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial (2017)
Conference Proceeding
Ogollah, R., Lewis, M., Konstantinou, K., Lawton, S., Garner, J., & Foster, N. (2017). The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial. . https://doi.org/10.1186/s13063-017-1902-y

Background Frequent data collection is desirable in randomised controlled trials (RCTs) where time‐to‐event is the primary outcome, in order to accurately capture the event of interest with reduced risk of recall bias. However, an inevitable problem... Read More about The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial.

The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial (2017)
Presentation / Conference
Ogollah, R., Lewis, M., Konstantinou, K., Lawton, S., Garner, J., & Foster, N. E. (2017, May). The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial. Poster presented at 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials, Liverpool, UK

Background Frequent data collection is desirable in randomised controlled trials (RCTs) where time-to-event is the primary outcome, in order to accurately capture the event of interest with reduced risk of recall bias. However, an inevitable problem... Read More about The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial.

Valuing productivity costs using the friction‐cost approach: Estimating friction‐period estimates by occupational classifications for the UK (2017)
Journal Article
Kigozi, J., Jowett, S., Lewis, M., Barton, P., & Coast, J. (2017). Valuing productivity costs using the friction‐cost approach: Estimating friction‐period estimates by occupational classifications for the UK. Health Economics, 26(12), 1862-1868. https://doi.org/10.1002/hec.3513

The friction cost approach has been proposed as an alternative to the human capital approach in estimating productivity costs. However, it is difficult, in practice, to apply this approach due to limited availability of context-specific data. Using n... Read More about Valuing productivity costs using the friction‐cost approach: Estimating friction‐period estimates by occupational classifications for the UK.

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). (2017)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Dunn, K. M., van der Windt, D., …Hay, E. M. (2017). The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). BMC Musculoskeletal Disorders, 18, Article 172. https://doi.org/10.1186/s12891-017-1513-5

BACKGROUND: Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of... Read More about The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)..

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care (2017)
Journal Article
Mallen, C. D., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., Jowett, S., …Peat, G. (2017). The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, e1002273 -?. https://doi.org/10.1371/journal.pmed.1002273

BACKGROUND: This study aimed to evaluate whether prompting general practitioners (GPs) to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis (OA) improves pain outcomes. METHODS AND FINDINGS: We conducted a... Read More about The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review. (2017)
Journal Article
Lewis. (2017). The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review. Value in Health, 496 - 506. https://doi.org/10.1016/j.jval.2016.12.006

OBJECTIVE: Given the significant costs of reduced productivity (presenteeism) in comparison to absenteeism, and overall societal costs, presenteeism has a potentially important role to play in economic evaluations. However, these costs are often excl... Read More about The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review..