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Heat Dissipation of Hybrid Iron Oxide-Gold Nanoparticles in an Agar Phantom (2015)
Journal Article
Curtis, A., Malekigorji, M., Holman, J., Skidmore, M., & Hoskins, C. (2015). Heat Dissipation of Hybrid Iron Oxide-Gold Nanoparticles in an Agar Phantom. Journal of Nanomedicine and Nanotechnology, 6(6), https://doi.org/10.4172/2157-7439.1000335

Hybrid iron oxide-gold nanoparticles (HNPs) have shown potential in cancer therapy as agents for tumour ablation and thermal switches for targeted drug release. Heat generation occurs by exploitation of the surface plasmon resonance of the gold coati... Read More about Heat Dissipation of Hybrid Iron Oxide-Gold Nanoparticles in an Agar Phantom.

Potential use of hybrid iron oxide gold nanoparticles as drug carriers (2015)
Book Chapter
Curtis, A., & Hoskins, C. Potential use of hybrid iron oxide gold nanoparticles as drug carriers. In Nano Based Drug Delivery (535-546). IAPC Publishing (International Association of Physical Chemists). https://doi.org/10.5599/obp.8.21

Hybrid nanoparticles are composed of more than one material fused together to increase functionality. These often consist of polymers coated onto the surface of metallic nanoparticles to render them useful in biomedicine [1,2]. In this chapter the te... Read More about Potential use of hybrid iron oxide gold nanoparticles as drug carriers.

Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents (2015)
Journal Article
Hoskins, C., & Curtis, A. D. Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents. Journal of Nanomedicine Research, 2(3), https://doi.org/10.15406/jnmr.2015.02.00028

Many drug molecules have low solubility in aqueous media and, hence, poor bioavailability. The formation of a host-guest complex with some other compound which has a good solubility profile can facilitate solubilization of hydrophobic drugs. Complex... Read More about Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents.

Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells (2014)
Journal Article
Malekigorji, M., Hoskins, C., Curtis, T., & Varbiro, G. Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells. Journal of Nanomedicine Research, 1(2), https://doi.org/10.15406/jnmr.2014.01.00010

Treatment of hepatocellular cancer with chemotherapeutic agents has limited success in clinical practice and their efficient IC50 concentration would require extremely high doses of drug administration which could not be tolerated due to systemic sid... Read More about Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells.

The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy (2014)
Journal Article
Malekigorji, M., DM Curtis, A., & Hoskins, C. The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy. Journal of Nanomedicine Research, 1(1), https://doi.org/10.15406/jnmr.2014.01.00004

Over the last decade major advances have been made in the treatment of cancer such as breast and leukaemia. However, no satisfactory progress has been made in the effective treatment of pancreatic cancer. Treatment of this disease is hindered by resi... Read More about The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy.

Preclinical evaluation of statins as a treatment for ovarian cancer (2013)
Journal Article
Robinson, E., Nandi, M., Wilkinson, L. L., Arrowsmith, D. M., Curtis, A. D., & Richardson, A. (2013). Preclinical evaluation of statins as a treatment for ovarian cancer. Gynecologic Oncology, 129(2), 417-424. https://doi.org/10.1016/j.ygyno.2013.02.003

Objective To evaluate the potential for statins to treat ovarian cancer. Methods The sensitivity of 7 ovarian cancer cell lines to either statins or statins combined with either carboplatin or paclitaxel was assessed using monolayer cultures. Se... Read More about Preclinical evaluation of statins as a treatment for ovarian cancer.