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All Outputs (14)

Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care (2017)
Journal Article
Heald, A. H., Livingston, M., Holland, D., Robinson, J., Moreno, G. Y., Donnahey, G., …Fryer, A. A. (2018). Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care. International Journal of Clinical Practice, 72(1), Article ARTN e13046. https://doi.org/10.1111/ijcp.13046

Introduction Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine disorders affecting women of reproductive age. We examined the specific tests that are done in primary care to lead to the diagnosis of PCOS, and to support the diagno... Read More about Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care.

Improving type 2 diabetes mellitus glycaemic outcomes is possible without spending more on medication: Lessons from the UK National Diabetes Audit (2017)
Journal Article
Heald, A. H., Livingston, M., Malipatil, N., Becher, M., Craig, J., Stedman, M., & Fryer, A. A. (2018). Improving type 2 diabetes mellitus glycaemic outcomes is possible without spending more on medication: Lessons from the UK National Diabetes Audit. Diabetes, Obesity and Metabolism, 20(1), 185-194. https://doi.org/10.1111/dom.13067

Aims To determine the factors at general practice level that relate to glycaemic control outcomes in people with type 2 diabetes (T2DM). Methods Data were accessed from 4050 general practices (50% of total) covering 1.6 million patients with T2D... Read More about Improving type 2 diabetes mellitus glycaemic outcomes is possible without spending more on medication: Lessons from the UK National Diabetes Audit.

Diagnosing gestational diabetes mellitus: implications of recent changes in diagnostic criteria and role of glycated haemoglobin (HbA1c) (2017)
Journal Article
Hanna, F. W., Duff, C. J., Shelley-Hitchen, A., Hodgson, E., & Fryer, A. A. (2017). Diagnosing gestational diabetes mellitus: implications of recent changes in diagnostic criteria and role of glycated haemoglobin (HbA1c). Clinical Medicine, 17(2), 108-113. https://doi.org/10.7861/clinmedicine.17-2-108

Gestational diabetes mellitus (GDM; approximately 5% of pregnancies) represents the most important risk factor for development of later-onset diabetes mellitus. We examined concordance between GDM diagnosis defined using the original 1999 World Healt... Read More about Diagnosing gestational diabetes mellitus: implications of recent changes in diagnostic criteria and role of glycated haemoglobin (HbA1c).

Monitoring Thyroid Function in Patients on Levothyroxine. Assessment of Conformity to National Guidance and Variability in Practice (2017)
Journal Article
Scargill, J. J., Livingston, M., Holland, D., Duff, C. J., Fryer, A. A., & Heald, A. H. (2017). Monitoring Thyroid Function in Patients on Levothyroxine. Assessment of Conformity to National Guidance and Variability in Practice. Experimental and Clinical Endocrinology and Diabetes, 125(9), 625-633. https://doi.org/10.1055/s-0043-103018

With demand for endocrine tests steadily increasing year-on-year, we examined thyroid function test (TFT) frequencies in patients on levothyroxine replacement therapy to assess the effect of initial TFT results and request source on TFT re-testing in... Read More about Monitoring Thyroid Function in Patients on Levothyroxine. Assessment of Conformity to National Guidance and Variability in Practice.

Socioeconomic Deprivation as Measured by the Index of Multiple Deprivation and Its Association with Low Sex Hormone Binding Globulin in Women. (2017)
Journal Article
Heald, A., Laing, I., McLernon, D. J., Donn, R., Hartland, A. J., Fryer, A. A., & Livingston, M. (2017). Socioeconomic Deprivation as Measured by the Index of Multiple Deprivation and Its Association with Low Sex Hormone Binding Globulin in Women. The Open Biochemistry Journal, 1 - 7. https://doi.org/10.2174/1874091X01711010001

OBJECTIVE: Sex hormone binding globulin (SHBG) is a marker of insulin resistance. Given established links between BMI and socioeconomic disadvantage, we investigated how SHBG varies by index of multiple deprivation (IMD). RESEARCH DESIGN AND METHODS:... Read More about Socioeconomic Deprivation as Measured by the Index of Multiple Deprivation and Its Association with Low Sex Hormone Binding Globulin in Women..

Socioeconomic deprivation as measured by the index of multiple deprivation and its association with low sex hormone binding globulin in women (2017)
Journal Article
Heald, A., Laing, I., McLernon, D. J., Donn, R., Hartland, A. J., Fryer, A. A., & Livingston, M. (2017). Socioeconomic deprivation as measured by the index of multiple deprivation and its association with low sex hormone binding globulin in women. The Open Biochemistry Journal, 11, 1-7. https://doi.org/10.2174/1874091X0171101000

Objective: Sex hormone binding globulin (SHBG) is a marker of insulin resistance. Given established links between BMI and socioeconomic disadvantage, we investigated how SHBG varies by index of multiple deprivation (IMD). Research Design and Meth... Read More about Socioeconomic deprivation as measured by the index of multiple deprivation and its association with low sex hormone binding globulin in women.

Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value (2017)
Presentation / Conference
Driskell, O., Duff, C., Holland, D., Waldron, J., Ford, C., Tran, M., …Heald, A. (2017, March). Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value. Poster presented at Diabetes UK Professional Conference 2017, Manchester, UK

Objectives: Studies have established that there is a clear link between monitoring frequency and diabetes control. Nevertheless, the wider question of optimum number of tests per year to attain target HbA1c remains unclear. Methods: Data on all Hb... Read More about Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value.

High rates of diabetes found in post-partum follow up of women with gestational diabetes, but screening rates still not high enough (2017)
Presentation / Conference
Ward, R., Hanna, F., Shelley-Hitchen, A., Hodgson, E., Heald, A., Fryer, A., & Duff, C. (2017, March). High rates of diabetes found in post-partum follow up of women with gestational diabetes, but screening rates still not high enough. Paper presented at Abstracts of the Diabetes UK Professional Conference 2017, Manchester, England, UK

Background: Women diagnosed with gestational diabetes (GDM) have elevated risk of developing Type 2 diabetes. NICE recommend women who develop GDM are screened 6 weeks post-partum and annually thereafter. Aims: To (i) evaluate conformity to guidan... Read More about High rates of diabetes found in post-partum follow up of women with gestational diabetes, but screening rates still not high enough.

Preeclampsia and Future Cardiovascular Health (2017)
Journal Article
Wu, P., Haththotuwa, R., Shing Kwok, C., Babu, A., Kotronias, R. A., Rushton, C., …Mamas, M. A. (2017). Preeclampsia and Future Cardiovascular Health. Circulation: Cardiovascular Quality and Outcomes, 10(2), https://doi.org/10.1161/circoutcomes.116.003497

Background— Preeclampsia is a pregnancy-specific disorder resulting in hypertension and multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy. We aimed to systematically evaluate and quantify the evidence on th... Read More about Preeclampsia and Future Cardiovascular Health.

Monitoring thyroid function in patients on levothyroxine: audit findings and suggested change in practice (2017)
Journal Article
Scargill, J. J., Livingston, M., Holland, D., Khan, A., Duff, C. J., Fryer, A. A., & Heald, A. H. (2017). Monitoring thyroid function in patients on levothyroxine: audit findings and suggested change in practice. International Journal of Clinical Practice, 71(1), Article ARTN e12877. https://doi.org/10.1111/ijcp.12877

With demand for endocrine tests steadily increasing year-on-year, review of requesting behaviour is very pertinent. A wealth of data now exists to suggest that there is a significant degree of unnecessary requesting of pathology tests,1-3 including e... Read More about Monitoring thyroid function in patients on levothyroxine: audit findings and suggested change in practice.

Social Disadvantage Is Associated With Lower Vitamin D Levels in Older People and There Is No Surrogate for Its Measurement (2017)
Journal Article
Heald, A. H., Anderson, S. G., Scargill, J. J., Short, A., Holland, D., Khan, A., …Livingston, M. (2017). Social Disadvantage Is Associated With Lower Vitamin D Levels in Older People and There Is No Surrogate for Its Measurement. Gerontology and Geriatric Medicine, https://doi.org/10.1177/2333721417697843

There is increasing evidence concerning adverse health consequences of low vitamin D levels. We determined whether there is any surrogate for measuring vitamin D in people older than 70 years and the relation between index of multiple deprivation (IM... Read More about Social Disadvantage Is Associated With Lower Vitamin D Levels in Older People and There Is No Surrogate for Its Measurement.