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Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective (2017)
Journal Article
Mallen, Prior, Roddy, & Muller. (2017). Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective. Revue du Rhumatisme, 84(5), 423-429. https://doi.org/10.1016/j.rhum.2017.05.004

Objectifs
Déterminer la prévalence de l’anxiété et de la dépression dans le contexte de la goutte, examiner les liens entre certaines caractéristiques de la goutte et ces comorbidités et identifier le rôle de l’allopurinol dans ces relations.

Mét... Read More about Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective.

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). (2017)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Dunn, K. M., van der Windt, D., …Hay, E. M. (2017). The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). BMC Musculoskeletal Disorders, 18, Article 172. https://doi.org/10.1186/s12891-017-1513-5

BACKGROUND: Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of... Read More about The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)..

183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY (2017)
Journal Article
Blagojevic-Bucknall, M., Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., & Roddy, E. (2017). 183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY. Rheumatology, 56(suppl_2), https://doi.org/10.1093/rheumatology/kex062.184

Background: Gout and obstructive sleep apnoea are both common problems in primary care and associated with considerable co-morbidity. Serum uric acid levels are frequently elevated in sleep apnoea patients and one previous cohort study found that peo... Read More about 183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY.

Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries (2017)
Journal Article
Mallen. (2017). Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. BMC Geriatrics, 93 -?. https://doi.org/10.1186/s12877-017-0486-4

BACKGROUND: In oldest-old patients (>80), few trials showed efficacy of treating hypertension and they included mostly the healthiest elderly. The resulting lack of knowledge has led to inconsistent guidelines, mainly based on systolic blood pressure... Read More about Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries.

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care (2017)
Journal Article
Mallen, C. D., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., Jowett, S., …Peat, G. (2017). The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, e1002273 -?. https://doi.org/10.1371/journal.pmed.1002273

BACKGROUND: This study aimed to evaluate whether prompting general practitioners (GPs) to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis (OA) improves pain outcomes. METHODS AND FINDINGS: We conducted a... Read More about The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink (2017)
Journal Article
Roddy, E., Muller, S., Paskins, Z., Hider, S., Blagojevic-Bucknall, M., & Mallen, C. (2017). Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink. Medicine, https://doi.org/10.1097/MD.0000000000006177

Oral bisphosphonates are the most commonly used drugs to treat postmenopausal osteoporosis. Acute pseudogout is anecdotally reported to occur following bisphosphonate initiation but empirical data are lacking. We investigated whether treatment with o... Read More about Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink.

Prognosis research ideally should measure time-varying predictors at their intended moment of use (2017)
Journal Article
Whittle, R., Royle, K., Jordan, K. P., Riley, R. D., Mallen, C. D., & Peat, G. (2017). Prognosis research ideally should measure time-varying predictors at their intended moment of use. Diagnostic and Prognostic Research, 1, Article 1. https://doi.org/10.1186/s41512-016-0006-6

Background
Prognosis research studies (e.g. those deriving prognostic models or examining potential predictors of outcome) often collect information on time-varying predictors after their intended moment of use, sometimes using a measurement method... Read More about Prognosis research ideally should measure time-varying predictors at their intended moment of use.

Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study (2017)
Journal Article
Tshimologo, M., Saunders, B., Muller, S., Mallen, C. D., & Hider, S. L. (2017). Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study. BMJ Open, e014301 -?. https://doi.org/10.1136/bmjopen-2016-014301

OBJECTIVE: To explore primary care polymyalgia rheumatica (PMR) patient beliefs about the causes of their PMR. DESIGN: Qualitative content analysis was conducted on patients' written responses to the question of what they thought had caused their PMR... Read More about Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study.

Generic prognostic factors for musculoskeletal pain in primary care: a systematic review. (2017)
Journal Article
Artus, M., Campbell, P., Mallen, C., Dunn, K., & van der Windt, D. (2017). Generic prognostic factors for musculoskeletal pain in primary care: a systematic review. BMJ Open, e012901 - ?. https://doi.org/10.1136/bmjopen-2016-012901

OBJECTIVES: To summarise the evidence for generic prognostic factors across a range of musculoskeletal (MSK) conditions. SETTING: primary care. METHODS AND OUTCOMES: Comprehensive systematic literature review. MEDLINE, CINAHL, PsychINFO and EMBASE we... Read More about Generic prognostic factors for musculoskeletal pain in primary care: a systematic review..

Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study (2017)
Journal Article
Mallen, C. (2017). Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study. Rheumatology, 736-744. https://doi.org/10.1093/rheumatology/kew468

Abstract Objectives: The objectives of this study were to examine changes in incidence and prevalence of RA between 1990 and 2014, and to explore if there is any geographic variation in incidence and prevalence of RA in the UK Methods: Design Prospec... Read More about Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study.

Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system (2016)
Journal Article
Mamas, M., & Mallen, C. (2016). Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system. Medicine, e4973. https://doi.org/10.1097/md.0000000000004973

Multimorbidity is common among older people and presents a major challenge to health systems worldwide. Metrics of multimorbidity are, however, crude: focusing on measuring comorbid conditions at single time-points rather than reflecting the longitud... Read More about Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system.

Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care. (2016)
Journal Article
Campbell, P., Hill, J., Protheroe, J., Afolabi, E., Lewis, M., Beardmore, R., …Dunn, K. (2016). Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care. Journal of Pain Research, 2016(9), 807 -818. https://doi.org/10.2147/JPR.S116614

Musculoskeletal conditions represent a considerable burden worldwide, and are predominantly managed in primary care. Evidence suggests that many musculoskeletal conditions share similar prognostic factors. Systematically assessing patient’s prognosis... Read More about Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care..

Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study (2016)
Journal Article
Walsh, C. P., Prior, J., Chandratre, P., Belcher, J., Mallen, C., & Roddy, E. (2016). Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study. BMC Musculoskeletal Disorders, 17, Article 394. https://doi.org/10.1186/s12891-016-1252-z

Background
Patients’ perceptions of their illness are dynamic and can directly influence aspects of management. Our aim was to examine the illness perceptions of gout patients in UK primary care and associations with allopurinol use.

Methods
A h... Read More about Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study.