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All Outputs (473)

Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study (2024)
Journal Article
Hay, C. A., Packham, J., Prior, J. A., Mallen, C. D., & Ryan, S. (2024). Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study. Rheumatology International, 44, 863–884. https://doi.org/10.1007/s00296-024-05554-z

Diagnosis of axial spondyloarthritis (axSpA) is frequently delayed for years after symptom onset. However, little is known about patient and healthcare professional (HCP) perspectives on barriers and facilitators in axSpA diagnosis. This study explor... Read More about Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study.

Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation (2024)
Journal Article
Abhishek, A., Grainge, M., Card, T., Williams, H. C., Taal, M. W., Aithal, G. P., …Riley, R. (2024). Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation. RMD Open, 10(1), Article e003980. https://doi.org/10.1136/rmdopen-2023-003980

Background: Sulfasalazine-induced cytopenia, nephrotoxicity and hepatotoxicity is uncommon during long-term treatment. Some guidelines recommend 3 monthly monitoring blood tests indefinitely during long-term treatment while others recommend stopping... Read More about Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation.

Health Literacy and Gout Characteristics in a Primary Care Cohort (2024)
Journal Article
Watson, L., Protheroe, J., Mallen, C., Muller, S., & Roddy, E. (2024). Health Literacy and Gout Characteristics in a Primary Care Cohort. Rheumatology Advances in Practice, 8(2), Article rkae034. https://doi.org/10.1093/rap/rkae034

Objectives
To examine the cross-sectional association between health literacy and gout characteristics.

Methods
In a primary care cohort of adults living with gout, the prevalence of poor health literacy was defined using the Single-Item Literac... Read More about Health Literacy and Gout Characteristics in a Primary Care Cohort.

“We have to change our mindsets”: a qualitative study of barriers and facilitators in research collaboration across integrated care system organisations (2024)
Journal Article
Gidlow, C. J., Sams, L., Buckless, K., Ellis, N. J., Duffy, H. C., Lambley-Burke, R., …Mallen, C. D. (2024). “We have to change our mindsets”: a qualitative study of barriers and facilitators in research collaboration across integrated care system organisations. BMC Health Services Research, 24(1), Article 264. https://doi.org/10.1186/s12913-024-10760-3

The introduction of Integrated Care Systems (ICS) in England aimed to increase joint planning and delivery of health and social care, and other services, to better meet the needs of local communities. There is an associated duty to undertake collabor... Read More about “We have to change our mindsets”: a qualitative study of barriers and facilitators in research collaboration across integrated care system organisations.

Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals (2024)
Journal Article
Simkins, J., Holden, M. A., Babatunde, O., White, S., Nicholls, E., Long, A., …O’Brien, N. (2024). Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals. Musculoskeletal Care, 22(1), Article e1873. https://doi.org/10.1002/msc.1873

Introduction
Osteoarthritis is the commonest form of chronic joint pain, which patients often self-manage before seeking healthcare advice. Patients frequently seek advice from community pharmacies, and a recent policy has recommended integrating co... Read More about Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals.

Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease. (2024)
Journal Article
Sokhal, B. S., Menon, S. P. K., Willes, C., Corp, N., Matetić, A., Mallen, C., & Mamas, M. (in press). Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease. Current Cardiology Reviews, 20(3), Article e290224227533. https://doi.org/10.2174/011573403X276647240217112151

There is limited systematic data on the association between the Hospital Frailty Risk Score (HFRS) and characteristics and mortality in patients with cerebrovascular and cardiovascular disease (CVD). This systematic review aimed to summarise the use... Read More about Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease..

Betwixt and between student and professional identities: UK medical students during COVID times (2024)
Journal Article
Polidano, K., Wenning, B., Mallen, C. D., & Dikomitis, L. (2024). Betwixt and between student and professional identities: UK medical students during COVID times. SN Social Sciences, 4(2), Article 53. https://doi.org/10.1007/s43545-024-00844-6

The COVID-19 pandemic lockdown in Spring 2020 brought about unprecedented disruption to medical education in the United Kingdom (UK). Medical students were encouraged to take up paid roles in the National Health Service to help with workforce shortag... Read More about Betwixt and between student and professional identities: UK medical students during COVID times.

Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England (2024)
Journal Article
Tajuria, G., Dobel-Ober, D., Bradley, E., Charnley, C., Lambley-Burke, R., Mallen, C., …Kingstone, T. (in press). Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England. BMC Medical Education, 24(1), Article 126. https://doi.org/10.1186/s12909-024-05059-0

Objectives
To evaluate the impact a novel education programme - to improve research engagement, awareness, understanding and confidence - had on a diverse health and social care workforce. Barriers and facilitators to engagement were explored togeth... Read More about Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England.

Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit (2024)
Journal Article
Swaithes, L., Paskins, Z., Finney, A., Walsh, N., Skrybant, M., Mallen, C., & Dziedzic, K. (2024). Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.01.003

Objective
Implementing clinical guidelines for osteoarthritis in primary care is complex. Whilst international guidelines detail what best practice for osteoarthritis looks like, little is known about how this is... Read More about Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit.

Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA) (2024)
Journal Article
Babatunde, O. O., Cottrell, E., White, S., Chudyk, A., Healey, E. L., Edwards, J., …Holden, M. A. (2024). Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA). BMC Musculoskeletal Disorders, 25(1), Article 54. https://doi.org/10.1186/s12891-023-07105-2

Background
Osteoarthritis is a common, painful and disabling long-term condition. Delivery of high-quality guideline-informed osteoarthritis care that successfully promotes and maintains supported self-management is imperative. However, osteoarthrit... Read More about Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA).

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update. (2024)
Journal Article
Moseng, T., Vliet Vlieland, T. P. M., Battista, S., Beckwée, D., Boyadzhieva, V., Conaghan, P. G., …Østerås, N. (in press). EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update. Annals of the Rheumatic Diseases, https://doi.org/10.1136/ard-2023-225041

Hip and knee osteoarthritis (OA) are increasingly common with a significant impact on individuals and society. Non-pharmacological treatments are considered essential to reduce pain and improve function and quality of life. EULAR recommendations for... Read More about EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update..

Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers (2024)
Journal Article
Pollock, K. G., Dickerson, C., Kainth, M., Lawton, S., Hurst, M., Sugrue, D. M., …Cohen, A. T. (in press). Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers. BMC Primary Care, 25(1), Article 7. https://doi.org/10.1186/s12875-023-02246-8

Background
Conducting effective and translational research can be challenging and few trials undertake formal reflection exercises and disseminate learnings from them. Following completion of our multicentre randomised controlled trial, which was im... Read More about Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers.

A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. (2024)
Journal Article
Bullock, L., Nicholls, E., Cherrington, A., Butler-Walley, S., Clark, E. M., Fleming, J., …Paskins, Z. (2024). A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. NIHR Open Research, 4(14), 14. https://doi.org/10.3310/nihropenres.13571.1

BackgroundGood quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person's life, beliefs, and value... Read More about A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol..

Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study (2024)
Journal Article
Shepherd, T., Robinson, M. E., Ramaema, M., Rakuoane, M., Moletsane, N., Mpholo, R., …Leigh, G. (2024). Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study. BMJ Public Health, 2(1), Article e000414. https://doi.org/10.1136/bmjph-2023-000414

Introduction: There is a growing body of research evidencing the detrimental impact of the COVID-19 pandemic on the mental health and well-being of young people. This impact may be worse in low-resource settings, especially those in sub-Saharan Afric... Read More about Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study.

Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey (2023)
Journal Article
Bullock, L., Abdelmagid, S., Fleming, J., Leyland, S., Clark, E. M., Gidlow, C., …Paskins, Z. (2023). Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey. Archives of Osteoporosis, 19(1), Article 5. https://doi.org/10.1007/s11657-023-01361-4

Summary
We conducted a survey of FLSs’ consultation conduct and content which identified marked variation in whether FLS HCPs discussed osteoporosis medicine with patients. A review of service pro formas showed more content related to ‘investigating... Read More about Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey.

Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development (2023)
Journal Article
Cornwall, N., Woodcock, C., Ashworth, J., Harrisson, S. A., Dikomitis, L., White, S., …on behalf of the PROMPPT team. (2023). Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development. British Journal of Pain, https://doi.org/10.1177/20494637231221688

Introduction
Regular review of patients prescribed opioids for persistent non-cancer pain (PCNP) is recommended but not routinely undertaken. The PROMPPT (Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain le... Read More about Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development.

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis (2023)
Journal Article
Kigozi, J., Oppong, R., Paskins, Z., Bromley, K., Lewis, M., Hughes, G., …Roddy, E. (2023). The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis. Rheumatology, https://doi.org/10.1093/rheumatology/kead659

Objectives. Evidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT) comprising... Read More about The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope (2023)
Journal Article
Md Yusof, M. Y., Smith, E. M. D., Ainsworth, S., Armon, K., Beresford, M. W., Brown, M., …Vital, E. M. (in press). Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 7(3), rkad093. https://doi.org/10.1093/rap/rkad093

Lay Summary: Systemic lupus erythematosus (SLE) is a lifelong condition in which the immune system damages the body’s own tissues, causing various symptoms including rashes, hair loss, mouth ulcers, joint pain and overwhelming tiredness. It can also... Read More about Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope.

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., …Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective
Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.