All Outputs (142)

SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018 (2020)
Presentation / Conference
Robinson, D., Craig, R., Lane, J., Andrew, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, August). SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020), Spain (virtual)

Objective: Recent RCTs have demonstrated little efficacy of certain shoulder surgeries. To investigate the trend in shoulder surgery incidence over time overall and by surgery type.

Methods: Data were obtained from UK primary care electronic healt... Read More about SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018.

Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study (2020)
Journal Article
Cai, Y., Graffy, J., Holman, D., Zhao, Z., Simmons, D., & Yu, D. (2021). Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study. Canadian Journal of Diabetes, 45(2), 179-185.e1. https://doi.org/10.1016/j.jcjd.2020.07.008

Objective
People with type 2 diabetes and increased systolic blood pressure (SBP) are at high risk of cardiovascular diseases (CVD). We aimed to investigate the association between CVD related hospital payments and SBP and test whether it is influen... Read More about Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study.

Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study (2020)
Journal Article
Ma, S., Cai, Y., Wang, Z., Zhao, Z., Xiao, J., & Yu, D. (2020). Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study. International Journal of Infectious Diseases, 99, 301-306. https://doi.org/10.1016/j.ijid.2020.08.009

Objectives
Early onset peritonitis (EOP) increases risk of clinical complications in patients initialising peritoneal dialysis (PD). This study aimed to develop and validate a risk prediction model for EOP among patients initialising PD.

Methods... Read More about Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study.

Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy (2020)
Journal Article
Zhuang, Y., Ding, C., Xu, Y., Ding, Z., & Yu, D. (2020). Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy. Blood Pressure Monitoring, https://doi.org/10.1097/MBP.0000000000000477

Objective
The trajectories of pulse pressure (PP) might affect the prognosis of malignant hypertensive nephropathy (MHN). We aimed to describe the association between PP trajectories and the future risk of end-stage renal disease and to identify and... Read More about Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy.

Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy (2020)
Journal Article
Zhuang, Y., Ding, C., Xu, Y., Ding, Z., & Yu, D. (2021). Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy. Blood Pressure Monitoring, 26(1), 14-21. https://doi.org/10.1097/MBP.0000000000000477

Objective The trajectories of pulse pressure (PP) might affect the prognosis of malignant hypertensive nephropathy (MHN). We aimed to describe the association between PP trajectories and the future risk of end-stage renal disease and to identify and... Read More about Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy.

Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys (2020)
Journal Article
Chen, Y., Chen, Y., Qin, R., Cai, Y., Bai, F., Yu, D., …Geng, B. (2021). Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys. Journal of Exercise Science and Fitness, 19(1), 8-12. https://doi.org/10.1016/j.jesf.2020.07.004

Background
Increased physical activity has been associated with reduced risks of various physical and mental conditions. However, the association between physical activity and liver health in the Chinese general adult population is not clear. This s... Read More about Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys.

Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults (2020)
Journal Article
Shi, R., Cai, Y., Yang, Y., Yu, D., & Qin, R. (2020). Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults. BMC Cardiovascular Disorders, 20, Article 347. https://doi.org/10.1186/s12872-020-01627-6

Background
There is uncertain evidence in the dose-response association between overall physical activity levels and clustering of cardiovascular diseases modifiable risk factors (CVDMRF) in Chinese adults. This study examined the hypothesis whether... Read More about Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults.

THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016 (2020)
Presentation / Conference
Robinson, D., Lane, J., Craig, R., Judge, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, June). THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016. Poster presented at EULAR 2020

Background: The lifetime prevalence of lower back pain is between 60% and 70%, with surgical treatments spared for those not responding to other options.

Objectives: To investigate the age, gender and socio-economic status differences in back pain... Read More about THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016.

Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study (2020)
Journal Article
Wang, Z., Yu, D., Cai, Y., Ma, S., Zhao, B., Zhao, Z., & Simmons, D. (2020). Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study. Medicine, 99(21), e20447 - e20447. https://doi.org/10.1097/MD.0000000000020447

Different measures of rates of transfer of glucose during the peritoneal equilibrium test (PET), undertaken during peritoneal dialysis (PD) might provide additional information regarding a patient's risk of future cardiovascular mortality. This study... Read More about Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study.

Risk of knee osteoarthritis after different types of knee injuries in young adults: a population-based cohort study. (2019)
Journal Article
Snoeker, B., Turkiewitz, A., Magnusson, K., Frobell, R., Yu, D., Peat, G., & Englund, M. (2019). Risk of knee osteoarthritis after different types of knee injuries in young adults: a population-based cohort study. British Journal of Sports Medicine, 54(12), 725-730. https://doi.org/10.1136/bjsports-2019-100959

Objectives
To estimate the risk of clinically-diagnosed knee osteoarthritis (OA) after different types of knee injuries in young adults.

Methods
In a longitudinal cohort study based on population-based healthcare data from Skåne, Sweden, we incl... Read More about Risk of knee osteoarthritis after different types of knee injuries in young adults: a population-based cohort study..

A low-cost laboratory-based method for predicting newly diagnosed biopsy-proven diabetic nephropathy in people with type 2 diabetes (2019)
Journal Article
Yu, D., Shang, J., Cai, Y., Wang, Z., Zhao, B., Zhao, Z., & Simmons, D. (2020). A low-cost laboratory-based method for predicting newly diagnosed biopsy-proven diabetic nephropathy in people with type 2 diabetes. Diabetic Medicine, 37(10), 1728-1736. https://doi.org/10.1111/dme.14195

Aims

To identify significant prognostic factors for newly diagnosed biopsy-proven diabetic nephropathy using routine laboratory measures, from which to derive a low-cost explanatory model, and to use this model to examine associations between the... Read More about A low-cost laboratory-based method for predicting newly diagnosed biopsy-proven diabetic nephropathy in people with type 2 diabetes.

The triglyceride glucose index can predict newly diagnosed biopsy-proven diabetic nephropathy in type 2 diabetes: A nested case control study (2019)
Journal Article
Simmons, D., Shang, J., Yu, D., Cai, Y., Wang, Z., Zhao, B., & Zhao, Z. (2019). The triglyceride glucose index can predict newly diagnosed biopsy-proven diabetic nephropathy in type 2 diabetes: A nested case control study. Medicine, 98(46), 1-7. https://doi.org/10.1097/md.0000000000017995

Insulin resistance is usually a key factor in the development of type 2 diabetes. The triglyceride glucose (TyG) index is a marker of insulin resistance which is also implicated in the risk of nephropathy among people with type 2 diabetes. This study... Read More about The triglyceride glucose index can predict newly diagnosed biopsy-proven diabetic nephropathy in type 2 diabetes: A nested case control study.

Derivation and external validation of a risk prediction algorithm to estimate future risk of cardiovascular death among patients with type 2 diabetes and incident diabetic nephropathy: prospective cohort study (2019)
Journal Article
Yu, D., Shang, J., Cai, Y., Zhang, X., Wang, Z., Zhao, B., …Simmons, D. (2019). Derivation and external validation of a risk prediction algorithm to estimate future risk of cardiovascular death among patients with type 2 diabetes and incident diabetic nephropathy: prospective cohort study. BMJ Open Diabetes Research and Care, 7(1), https://doi.org/10.1136/bmjdrc-2019-000735

Objective
To derive, and externally validate, a risk score for cardiovascular death among patients with type 2 diabetes and newly diagnosed diabetic nephropathy (DN).

Research design and methods
Two independent prospective cohorts with type 2 di... Read More about Derivation and external validation of a risk prediction algorithm to estimate future risk of cardiovascular death among patients with type 2 diabetes and incident diabetic nephropathy: prospective cohort study.

Opioid use, postoperative complications, and implant survival after unicompartmental versus total knee replacement: a population-based network study (2019)
Journal Article
Yu, D. (2019). Opioid use, postoperative complications, and implant survival after unicompartmental versus total knee replacement: a population-based network study. The Lancet Rheumatology, 1(4), e229-e236. https://doi.org/10.1016/S2665-9913%2819%2930075-X

Background
There is uncertainty around whether to use unicompartmental knee replacement (UKR) or total knee replacement (TKR) for individuals with osteoarthritis confined to a single compartment of the knee. We aimed to emulate the design of the Tot... Read More about Opioid use, postoperative complications, and implant survival after unicompartmental versus total knee replacement: a population-based network study.

Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis (2019)
Journal Article
Thomas, M., Yu, D., Nicholls, E., Bierma‐Zeinstra, S., Conaghan, P. G., Stoner, K. J., …Peat, G. (2020). Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis. Arthritis Care and Research, 72(12), 1687-1692. https://doi.org/10.1002/acr.24088

Objective
To identify distinct recovery trajectories of acute flares of knee pain and associated participant characteristics.

Methods
Data were from FLARE RCT, a multicentre trial in 27 primary care centres in UK and Netherlands of three regimes... Read More about Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis.

Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care (2019)
Journal Article
Appleyard, T., Ashworth, J., Bedson, J., Yu, D., & Peat, G. (2019). Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care. Osteoarthritis and Cartilage, 1437-1444. https://doi.org/10.1016/j.joca.2019.06.008

Summary Objective
To investigate trends in gabapentinoid prescribing in patients with osteoarthritis (OA).

Methods
Patients aged 40 years and over with a new OA diagnosis recorded between 1995 and 2015 were identified in the Clinical Practice Re... Read More about Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care.

Comparison of Clinical Trial Changes in Primary Outcome and Reported Intervention Effect Size Between Trial Registration and Publication (2019)
Journal Article
Yu. (2019). Comparison of Clinical Trial Changes in Primary Outcome and Reported Intervention Effect Size Between Trial Registration and Publication. Jama Network Open, 2(7), Article e197242. https://doi.org/10.1001/jamanetworkopen.2019.7242

IMPORTANCE
Primary outcome change could threaten the validity of a clinical trial; however, evidence about the consequences on the reported intervention effect size is unclear.

OBJECTIVES
To examine the status of randomized clinical trials whose... Read More about Comparison of Clinical Trial Changes in Primary Outcome and Reported Intervention Effect Size Between Trial Registration and Publication.

Triglyceride Glucose Index Predicting Cardiovascular Mortality in Chinese Initiating Peritoneal Dialysis: A Cohort Study (2019)
Journal Article
Yu. (2019). Triglyceride Glucose Index Predicting Cardiovascular Mortality in Chinese Initiating Peritoneal Dialysis: A Cohort Study. Kidney and Blood Pressure Research, 44(4), 669-678. https://doi.org/10.1159/000500979

Background:
Insulin resistance (IR) is increased among people with end-stage renal disease (ESRD). The Triglyceride glucose (TyG) index is a marker of IR and is also associated with the prognosis of cardiovascular disease among patients initiating p... Read More about Triglyceride Glucose Index Predicting Cardiovascular Mortality in Chinese Initiating Peritoneal Dialysis: A Cohort Study.

Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study. (2019)
Journal Article
Yu. (2019). Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study. Medicine, 98(27), Article e16340. https://doi.org/10.1097/MD.0000000000016340

Cardiovascular disease (CVD) is the leading cause of death in patients with end-stage renal disease (ESRD) treated by dialysis. Pulse pressure (PP) as an independent prognostic factor of cardiovascular risk might be clinically implicated in predictin... Read More about Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study..

Development And External Validation Of A Patient-level Prediction Model For 60-day Mortality Following Total Knee Arthroplasty: A Multinational Cohort Study (2019)
Journal Article
Yu. (2019). Development And External Validation Of A Patient-level Prediction Model For 60-day Mortality Following Total Knee Arthroplasty: A Multinational Cohort Study. Osteoporosis International, S178 -S179. https://doi.org/10.1101/2020.12.14.20240994

Objective
Total knee replacement (TKR) is the most effective intervention available for the treatment of severe knee osteoarthritis. A small proportion of patients undergoing TKR are at risk of postoperative complications. We aimed to develop and ex... Read More about Development And External Validation Of A Patient-level Prediction Model For 60-day Mortality Following Total Knee Arthroplasty: A Multinational Cohort Study.