All Outputs (2)

Electrospun Polycaprolactone (PCL) Nanofibers Induce Elongation and Alignment of Co-Cultured Primary Cortical Astrocytes and Neurons (2025)
Journal Article
Nutt, K., Dombros-Ryan, Z., Birea, R., Franks, E. V., Eastham, S., Godwin, M., …Jenkins, S. I. (in press). Electrospun Polycaprolactone (PCL) Nanofibers Induce Elongation and Alignment of Co-Cultured Primary Cortical Astrocytes and Neurons. Micromachines, 16(3), Article 256. https://doi.org/10.3390/mi16030256

Neuromimetic in vitro models, simulating in vivo architecture/organization, are urgently needed to reduce experimental reliance on live animals. Our group recently reported a novel brain tissue derivation protocol, simultaneously deriving all major c... Read More about Electrospun Polycaprolactone (PCL) Nanofibers Induce Elongation and Alignment of Co-Cultured Primary Cortical Astrocytes and Neurons.

A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts. (2025)
Journal Article
Wiseman, J., Basit, R. H., Suto, A., Middya, S., Kabiri, B., Evans, M., …Chari, D. M. (in press). A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts. Neural Regeneration Research, 20(12), 3539-3552. https://doi.org/10.4103/NRR.NRR-D-24-00422

Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies. Biomaterial therapies show promise as medical materials for neural repair through immunomodulation, structural support, and delivery of t... Read More about A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts..