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All Outputs (258)

Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study (2023)
Journal Article
Sokhal, B. S., Matetić, A., Abhishek, A., Banerjee, A., Partington, R., Roddy, E., …Mamas, M. A. (2023). Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study. American Journal of Cardiology, 206, 210-218. https://doi.org/10.1016/j.amjcard.2023.08.138

Data are limited on whether the causes of emergency department (ED) encounters for cardiovascular diseases (CVDs) and associated clinical outcomes vary by frailty status. Using the United States Nationwide ED Sample, selected CVD encounters (acute my... Read More about Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study.

Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY (2023)
Journal Article
Russell, M. D., Massey, J., Roddy, E., MacKenna, B., Bacon, S., Goldacre, B., …Galloway, J. B. (2023). Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY. The Lancet Rheumatology, 5(10), e622-e632. https://doi.org/10.1016/S2665-9913%2823%2900206-0

Background Gout is the most prevalent inflammatory arthritis, yet one of the worst managed. Our objective was to assess how the COVID-19 pandemic impacted incidence and quality of care for people with gout in England, UK. Methods With the approv... Read More about Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY.

Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot (2023)
Journal Article
Lithgow, M. J., Buldt, A. K., Munteanu, S. E., Marshall, M. M., Thomas, M. J., Peat, G., …Menz, H. B. (in press). Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot. Arthritis Care & Research, 10.1002/acr.25217. https://doi.org/10.1002/acr.25217

To compare radiographic measures of foot structure between people with and without symptomatic radiographic midfoot osteoarthritis (OA). This was a cross-sectional study of adults aged ≥50 years registered with four UK general practices who reported... Read More about Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot.

POS0508 A RANDOMISED CONTROLLED TRIAL COMPARING ANAKINRA VERSUS STEROIDS FOR THE TREATMENT OF GOUT ATTACKS IN PEOPLE WITH RENAL DISEASE (ASGARD): A FEASIBILITY STUDY (2023)
Presentation / Conference
Balasubramaniam, G., Almond, M., Harnett, P., Zhang, J., Turner, D., Scales, J., …Dasgupta, B. (2023, May). POS0508 A RANDOMISED CONTROLLED TRIAL COMPARING ANAKINRA VERSUS STEROIDS FOR THE TREATMENT OF GOUT ATTACKS IN PEOPLE WITH RENAL DISEASE (ASGARD): A FEASIBILITY STUDY. Paper presented at EULAR 2023 European Congress of Rheumatology, Milan, Italy

P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study (2023)
Presentation / Conference
Padmanabhan, N., Muller, S., Bailey, J., Helliwell, T., Mackie, S. L., Mallen, C. D., & Roddy, E. (2023, April). P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Giant cell arteritis (GCA) is considered a medical emergency, and relapses are common, affecting around 50% of patients. Many of the early symptoms of GCA are non-specific and highly prevalent in older people, making the diagnosis challenging. The... Read More about P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study.

P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies (2023)
Presentation / Conference
Watson, L., Cornwall, N., Jinks, C., Bradbury, K., Goff, L., Little, P., …Roddy, E. (2023, April). P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Background/Aims Lifestyle, especially diet and alcohol, has been implicated in the causation of gout for centuries and the dietary factors which may trigger flares remain of great interest to people living with gout and their families. However, ther... Read More about P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies.

Neuropathic Pain Associated With First Metatarsophalangeal Joint Osteoarthritis: Frequency and Associated Factors (2023)
Journal Article
Menz, H. B., Allan, J. J., Buldt, A. K., Landorf, K. B., Cicuttini, F. M., Roddy, E., & Munteanu, S. E. (2023). Neuropathic Pain Associated With First Metatarsophalangeal Joint Osteoarthritis: Frequency and Associated Factors. Arthritis Care and Research, 75(10), 2127-2133. https://doi.org/10.1002/acr.25125

OBJECTIVE: To determine whether neuropathic pain is a feature of first metatarsophalangeal (MTP) joint osteoarthritis (OA). METHODS: Ninety-eight participants (mean age 57.4?years, standard deviation 10.3) with symptomatic radiographic first MTP join... Read More about Neuropathic Pain Associated With First Metatarsophalangeal Joint Osteoarthritis: Frequency and Associated Factors.

what factors require consideration when individualising exercise interventions for people with osteoarthritis? Consensus of experts using a delphi methodology (2023)
Presentation / Conference
Yaseen, K., Zhang, W., Doherty, M., Abhishek, A., Jamtvedt, G., Martinez, M., …Hall, M. (2023, March). what factors require consideration when individualising exercise interventions for people with osteoarthritis? Consensus of experts using a delphi methodology. Poster presented at 2023 OARSI World Congress on Osteoarthritis, Sheraton Denver Downtown Hotel, Denver, USA

Exploring the longer-term impact of the COVID-19 pandemic on physical and mental health of people with inflammatory rheumatic diseases: a cross-sectional survey (2023)
Journal Article
Muller, Hider, Paskins, & Roddy. (2023). Exploring the longer-term impact of the COVID-19 pandemic on physical and mental health of people with inflammatory rheumatic diseases: a cross-sectional survey. Clinical Rheumatology, 42, 1903-1909. https://doi.org/10.1007/s10067-023-06565-0

OBJECTIVE: To assess the longer term impact of the COVID-19 pandemic on the self-reported physical and mental health of people with inflammatory rheumatic diseases (IRDs). METHODS: Two thousand twenty-four patients with IRDs were randomly selected fr... Read More about Exploring the longer-term impact of the COVID-19 pandemic on physical and mental health of people with inflammatory rheumatic diseases: a cross-sectional survey.

Sex and country differences in gout: cross-country comparison between Sweden and the UK (2023)
Journal Article
Dehlin, M., Muller, S., Mallen, C., Landgren, A., Watson, L., Jacobsson, L., & Roddy, E. (2023). Sex and country differences in gout: cross-country comparison between Sweden and the UK. Scandinavian Journal of Rheumatology, 52(6), 673-682. https://doi.org/10.1080/03009742.2023.2177383

OBJECTIVE: Compare characteristics, sex differences, and management of gout in Sweden and the UK. METHOD: The results from two separate primary care gout surveys from Sweden and the UK were compared. Participants aged =18 years with gout were sent a... Read More about Sex and country differences in gout: cross-country comparison between Sweden and the UK.

Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases (2023)
Journal Article
Hider, S., Muller, S., Gray, L., Manning, F., Heining, D., Menon, A., …Paskins, Z. (2023). Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases. Rheumatology Advances in Practice, 7(1), https://doi.org/10.1093/rap/rkac109

Objectives: COVID-19 led to rapid uptake of digital healthcare. We sought to examine digital access, health and digital literacy, and impact on confidence and satisfaction with remote consultations in people with inflammatory rheumatic diseases (IRDs... Read More about Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases.

Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., …Roddy, E. (2022). Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care. Rheumatology, 62(8), 2748-2756. https://doi.org/10.1093/rheumatology/keac706

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Presentation / Conference
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., …Major, T. (2022, November). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Presented at ACR Convergence 2022

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (≤13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. (2022)
Journal Article
Roddy, E., Russell, M. D., Rutherford, A. I., Ellis, B., Norton, S., Douiri, A., …Galloway, J. B. (2023). Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. Rheumatology, 62(7), 2426-2434. https://doi.org/10.1093/rheumatology/keac638

Objective To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalizations for gout. Methods Using linked Clinical Practice Research Datalink and NHS Digital Hospital Episode Statistics data, we described the inci... Read More about Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England..

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., …Williams, E. (2022). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), e48-e88. https://doi.org/10.1093/rheumatology/keac551

Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. (2022)
Journal Article
Roddy, E. (2022). Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. Arthritis and Rheumatology, 75(5), 816-825. https://doi.org/10.1002/art.42393

OBJECTIVE: To determine whether a gout polygenic risk score (PRS) associates with age at gout onset and tophaceous disease in European (EUR), East Polynesian (EP), and West Polynesian (WP) men/women with gout. METHODS: A 19-variant gout PRS was p... Read More about Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout..

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Journal Article
Roddy. (2022). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Arthritis and Rheumatology, 3338 - 3341

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (=13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.