Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study

Protheroe, J; Saunders, B; Bartlam, B; Dunn, KM; Cooper, V; Campbell, P; Hill, JC; Tooth, S; Mallen, CD; Hay, E; Foster, NE

doi:10.1186/s12891-019-2587-z

Supporting self-management of low back pain with an internet intervention with and without telephone support in primary care (SupportBack 2): a randomised controlled trial of clinical and cost-effectiveness (2024)
Journal Article
Geraghty, A. W., Becque, T., Roberts, L. C., Hill, J. C., Foster, N. E., Yardley, L., …Little, P. (2024). Supporting self-management of low back pain with an internet intervention with and without telephone support in primary care (SupportBack 2): a randomised controlled trial of clinical and cost-effectiveness. The Lancet Rheumatology, 6(7), e424-e437. https://doi.org/10.1016/s2665-9913%2824%2900086-9

Background
Low back pain is prevalent and a leading cause of disability. We aimed to determine the clinical and cost-effectiveness of an accessible, scalable internet intervention for supporting behavioural self-management (SupportBack).

Methods... Read More about Supporting self-management of low back pain with an internet intervention with and without telephone support in primary care (SupportBack 2): a randomised controlled trial of clinical and cost-effectiveness.

The acceptability and feasibility of conducting a randomised controlled trial to test the effectiveness of a walking intervention for older people with persistent musculoskeletal pain in primary care: A mixed methods evaluation of the iPOPP pilot trial (2023)
Journal Article
Healey, E. L., McBeth, J., Nicholls, E., Chew‐Graham, C. A., Dent, S., Foster, N. E., …Jinks, C. (2023). The acceptability and feasibility of conducting a randomised controlled trial to test the effectiveness of a walking intervention for older people with persistent musculoskeletal pain in primary care: A mixed methods evaluation of the iPOPP pilot trial. Musculoskeletal Care, https://doi.org/10.1002/msc.1815

Introduction: Persistent musculoskeletal (MSK) pain is associated with physical inactivity in older people. While walking is an acceptable form of physical activity, the effectiveness of walking interventions in this population has yet to be establis... Read More about The acceptability and feasibility of conducting a randomised controlled trial to test the effectiveness of a walking intervention for older people with persistent musculoskeletal pain in primary care: A mixed methods evaluation of the iPOPP pilot trial.

Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). (2023)
Journal Article
Foster, N. E., Nicholls, E., Holden, M. A., Healey, E. L., Hay, E. M., & trial team, T. B. (2023). Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). Archives of Rehabilitation Research and Clinical Translation, 5(2), Article 100266. https://doi.org/10.1016/j.arrct.2023.100266

To investigate whether knee osteoarthritis (OA) related pain and function can be improved by offering enhanced physical therapist-led exercise interventions. Three-arm prospectively designed pragmatic randomized controlled trial. General practices an... Read More about Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial)..

Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial (2022)
Journal Article
Hill, J. C., Garvin, S., Bromley, K., Saunders, B., Kigozi, J., Cooper, V., …Foster, N. E. (2022). Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial. The Lancet Rheumatology, 4(9), e591 - e602. https://doi.org/10.1016/S2665-9913%2822%2900159-X

Background Risk-based stratified care shows clinical effectiveness and cost-effectiveness versus usual primary care for non-specific low back pain but is untested for other common musculoskeletal disorders. We aimed to test the clinical effectiveness... Read More about Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial.

The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial (2022)
Journal Article
Burton, C., Rathod-Mistry, T., Blackburn, S., Blagojevic-Bucknall, M., Bucknall, M., Chesterton, L., …Roddy, E. (2023). The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial. Rheumatology, 62(2), 546–554. https://doi.org/10.1093/rheumatology/keac219

Objectives
This follow-up study of the INSTinCTS (INjection vs SplinTing in Carpal Tunnel Syndrome) trial compared the effects of corticosteroid injection (CSI) and night splinting (NS) for the initial management of mild-to-moderate carpal tunnel sy... Read More about The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial.

Refinement and validation of a tool for stratifying patients with musculoskeletal pain (2021)
Journal Article
Dunn, K. M., Campbell, P., Lewis, M., Hill, J. C., van der Windt, D. A., Afolabi, E., …Foster, N. E. (2021). Refinement and validation of a tool for stratifying patients with musculoskeletal pain. European Journal of Pain, 25(10), 2081-2093. https://doi.org/10.1002/ejp.1821

AbstractBackgroundPatients with musculoskeletal pain in different body sites share common prognostic factors. Using prognosis to stratify and treatment match can be clinically and cost‐effective. We aimed to refine and validate the Keele STarT MSK To... Read More about Refinement and validation of a tool for stratifying patients with musculoskeletal pain.

The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome. (2021)
Journal Article
Oppong, R., Jowett, S., Lewis, M., Roddy, E., Ogollah, R. O., Zwierska, I., …Foster, N. E. (2021). The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome. Rheumatology, 60(9), 4175-4184. https://doi.org/10.1093/rheumatology/keaa903

OBJECTIVES: To determine whether physiotherapist-led exercise intervention and ultrasound-guided subacromial corticosteroid injection is cost-effective when compared with standard advice and exercise leaflet and unguided injection in patients with su... Read More about The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome..

Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportBack 2). (2020)
Journal Article
Geraghty, A. W. A., Roberts, L., Hill, J., Foster, N. E., Yardley, L., Hay, E., …Little, P. (2020). Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportBack 2). BMJ Open, 10(8), https://doi.org/10.1136/bmjopen-2020-040543

INTRODUCTION: Self-management and remaining physically active are first-line recommendations for the care of patients with low back pain (LBP). With a lifetime prevalence of up to 85%, novel approaches to support behavioural self-management are neede... Read More about Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportBack 2)..

Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial. (2020)
Journal Article
Roddy, E., Ogollah, R., Oppong, R., Zwierska, I., Datta, P., Hall, A., …Foster, N. (2020). Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial. British Journal of Sports Medicine, 55(5), https://doi.org/10.1136/bjsports-2019-101268

OBJECTIVES: To compare the clinical effectiveness of (1) physiotherapist-led exercise versus an exercise leaflet, and (2) ultrasound-guided subacromial corticosteroid injection versus unguided injection for pain and function in subacromial pain (form... Read More about Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial..

Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Bartlam, B., …Foster, N. E. (2020). Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. JMIR Research Protocols, 9(7), https://doi.org/10.2196/17939

BACKGROUND: Musculoskeletal (MSK) pain is a major cause of pain and disability. We previously developed a prognostic tool (STarT Back Tool) with demonstrated effectiveness in guiding primary care low back pain management by supporting decision-making... Read More about Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial..

Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial (2020)
Journal Article
Konstantinou, K., Lewis, M., Dunn, K., Hay, E., Van Der Windt, D., Artus, M., …Foster, N. (2020). Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial. The Lancet Rheumatology, 2(7), e401-e411. https://doi.org/10.1016/S2665-9913%2820%2930099-0

Background
Sciatica has a substantial impact on individuals and society. Stratified care has been shown to lead to better outcomes among patients with non-specific low back pain, but it has not been tested for sciatica. We aimed to investigate the c... Read More about Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial.

Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT (2020)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Saunders, B., Kigozi, J., …Dunn, K. M. (2020). Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT. Health Technology Assessment, 2(7), e401-e411. https://doi.org/10.3310/hta24490

BACKGROUND: Sciatica has a substantial impact on patients and society. Current care is 'stepped', comprising an initial period of simple measures of advice and analgesia, for most patients, commonly followed by physiotherapy, and then by more intensi... Read More about Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT.

Identifying potential moderators of first-line treatment effect in patients with musculoskeletal shoulder pain: a systematic review (2020)
Journal Article
McRobert, C. J., Hill, J. C., Hay, E. M., & van der Windt, D. A. (2022). Identifying potential moderators of first-line treatment effect in patients with musculoskeletal shoulder pain: a systematic review. European Journal of Physiotherapy, 24(1), 1-15. https://doi.org/10.1080/21679169.2020.1752304

P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial (2020)
Journal Article
Burton, C. L., Rathod-Mistry, T., Blagojevic-Bucknall, M., Chesterton, L. S., Davenport, G., Dziedzic, K. S., …Roddy, E. (2020). P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial. Rheumatology, 59(Supplement_2), https://doi.org/10.1093/rheumatology/keaa111.138

Background
Patients with mild-to-moderate carpal tunnel syndrome (CTS) are commonly treated with night splints and/or local corticosteroid injection. In the INSTINCTS (INjection versus SplinTing in Carpal Tunnel Syndrome) trial, we previously report... Read More about P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial.

Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Saunders, B., …Foster, N. E. (2020). Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial. BMC Family Practice, 21, Article 30. https://doi.org/10.1186/s12875-019-1074-9

Background: Musculoskeletal (MSK) pain from the five most common presentations to primary care (back, neck, shoulder, knee or multi-site pain), where the majority of patients are managed, is a costly global health challenge. At present, first-line de... Read More about Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial.

Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care. (2019)
Journal Article
Geraghty, A. W. A., Roberts, L. C., Stanford, R., Hill, J. C., Yoganantham, D., Little, P., …Yardley, L. (2020). Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care. Pain Medicine, 21(9), https://doi.org/10.1093/pm/pnz312

OBJECTIVE: We explored patients' experiences of using Internet-based self-management support for low back pain (LBP) in primary care, with and without physiotherapist telephone guidance. DESIGN: Exploratory descriptive qualitative study using themati... Read More about Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care..

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Bucknall, M., Mehta, R., Oppong, R., Avery, A., …Mallen, C. (2019). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, 79(2), https://doi.org/10.1136/annrheumdis-2019-216154

OBJECTIVES: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care.

METHODS: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general prac... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways. (2019)
Journal Article
Price, A., Ogollah, R., Kang, S., Hay, E., Barker, K., Benedetto, E., …Hill, J. (2019). Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways. BMJ Open, 9(10), https://doi.org/10.1136/bmjopen-2018-025357

OBJECTIVES
We have previously developed and validated the Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways, showing encouraging psychometric test results. The objective of this study wa... Read More about Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways..

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm (2019)
Journal Article
Konstantinou, K., Dunn, K., Windt, D., Ogollah, R., Jasani, V., & Foster, N. (2019). Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2686-x

Background
Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in... Read More about Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm.

Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study (2019)
Journal Article
Protheroe, J., Saunders, B., Bartlam, B., Dunn, K., Cooper, V., Campbell, P., …Foster, N. (2019). Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2587-z

Background
Musculoskeletal (MSK) pain represents a considerable worldwide healthcare burden. This study aimed to gain consensus from practitioners who work with MSK pain patients, on the most appropriate primary care treatment options for subgroups... Read More about Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study.

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