All Outputs (91)

Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2025)
Journal Article
Alabas, O., Mason, K. J., Barker, J., Morrison, S., Yiu, Z., Bewley, A., …Zietemann, V. (2025). Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, https://doi.org/10.1093/bjd/ljaf017

The current management of psoriasis does not differentiate between young and old patients in selecting the safest and/or most effective biologic. To explore the effect of age at treatment initiation in response to biologics in patients with moderate-... Read More about Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR) (2024)
Journal Article
Williams, K., Lada, G., Reynolds, N. J., Mcelhone, K., Evans, I., Warren, R. B., …Kleyn, C. E. (2024). Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR). Clinical and Experimental Dermatology, https://doi.org/10.1093/ced/llae449

Psoriasis is associated with poor mental health and reduced quality of life. Although the high risk for depression in patients with psoriasis is well-established, their suicidality risk is uncertain. Previous studies provide contrasting results and h... Read More about Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR).

Association of air pollution from a landfill site with primary care consultation (2024)
Working Paper
Jordan, K. P., Muller, S., Usman, M., Bailey, J., Burton, C., Lawton, S. A., …van der Windt, D. A. Association of air pollution from a landfill site with primary care consultation

Background Waste landfill sites are associated with gaseous emissions and this air pollution can cause unpleasant smells (“malodour”). This causes concerns about its impact on the health of the local population. This study assessed change in general... Read More about Association of air pollution from a landfill site with primary care consultation.

Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data (2024)
Journal Article
Akthar, M., Mason, K. J., & Scott, I. C. (2024). Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data. Musculoskeletal Care, 22(3), Article e1916. https://doi.org/10.1002/msc.1916

Objective: The Internet has transformed how patients access health information. We examined Google search engine data to understand which aspects of health are most often searched for in combination with inflammatory arthritis (IA). Methods: Using Go... Read More about Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data.

Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study) (2024)
Presentation / Conference
Jenkinson, D., Bailey, J., Mughal, F., Dunn, K., & Mason, K. (2024, July). Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study). Presented at SAPC ASM 2024, Bristol

SNOMED Clinical terminology and Clinical Practice Record Datalink (CPRD) AURUM dataset code lists from the CLIMB Study:

The aim of the CLIMB study is to investigate whether children and young people (aged 8-18 years) with musculoskeletal pain are... Read More about Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study).

P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Poster presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

There are long-standing concerns that the use of biologic therapies to treat patients with psoriasis could confer an increased risk of developing cancer due to their immunomodulatory effects. We aimed to assess the risk of any incident cancer (exclud... Read More about P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

Previous literature suggests an association between the use of biologics and the development of keratinocyte carcinoma in psoriasis. Our aim was to evaluate the risks of developing basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC... Read More about O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2024)
Journal Article
Williams, K., Lada, G., Reynolds, N., Mcelhone, K., Evans, I., Walton, S., …Kleyn, C. E. (2024). PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 191(Supplement_1), i177-i177. https://doi.org/10.1093/bjd/ljae090.375

Psoriasis is associated with poor mental health, high prevalence of depression and reduced quality of life. However, suicide risk in this group is unclear. Previous meta-analyses have provided conflicting results regarding risk of suicidality outcome... Read More about PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study (2024)
Presentation / Conference
Mason, K. J., Jordan, K. P., Bailey, J., Jöud, A., Jowett, S., Protheroe, J., …Dunn, K. M. (2024, April). P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims
Musculoskeletal pain in childhood increases the risk of such pain in adulthood but there is an absence of management guidance for this group, not helped by a lack of evidence on the extent and nature of pain in children. The aim was... Read More about P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study.

P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data (2024)
Presentation / Conference
Akthar, M., Mason, K. J., & Scott, I. C. (2024, April). P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Inflammatory arthritis (IA) care involves a paradox. Rheumatologists focus on reducing disease activity through treat-to-target (T2T). But surveys/qualitative studies show patients’ main concern is pain. As these studies include a min... Read More about P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data.

Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. (2024)
Journal Article
Ghosal, S., Heron, N., Mason, K., Bailey, J., & Jordan, K. (2024). Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. British Journal of General Practice (BJGP), BJGP.2023.0684. https://doi.org/10.3399/bjgp.2023.0684

Orlistat is recommended as an adjunct to diet and exercise for weight loss in type 2 diabetes mellitus (T2DM). The aims were to explore (i) associations between patient characteristics and orlistat prescribing and to determine (ii) associations of or... Read More about Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study..

The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2023)
Journal Article
Alabas, O. A., Mason, K. J., Yiu, Z. Z. N., Warren, R. B., Dand, N., Barker, J. N., …Warren, R. B. (2024). The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 190(5), 689–700. https://doi.org/10.1093/bjd/ljad481

Background
Few studies have used real-world data to investigate the association between biologic therapy survival and age at psoriasis onset or HLA-C*06:02 status in patients with moderate-to-severe psoriasis. The robustness of these studies is limi... Read More about The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., …Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective
Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.

Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study (2023)
Journal Article
Mason, K. J., Alabas, O. A., Dand, N., Warren, R. B., Reynolds, N. J., Barker, J. N. W. N., …Warren, R. (2024). Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study. British Journal of Dermatology, 190(3), 441–444. https://doi.org/10.1093/bjd/ljad446

It is unknown why some psoriasis patients experience long-term effectiveness with their first biologic monotherapy. Our aim was to compare the baseline demographic, disease, genotypic, clinical and lifestyle characteristics of patients with psoriasis... Read More about Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study.

Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists (2023)
Dataset
Jordan, K., Mason, K., Bailey, J., Protheroe, J., Mughal, F., Thomas, M., …Dunn, K. (2023). Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists. [Dataset]

SNOMED Clinical terminology and Clinical Practice Record Datalink (CPRD) AURUM dataset code lists from CAM-Pain programme 2023:

The aim of the CAM-Pain programme is to improve the understanding, self-management, impact and healthcare of musculoske... Read More about Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists.

Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study (2023)
Journal Article
Png, M. E., Mason, K. J., Marshall, M., Jordan, K. P., Bailey, J., Frisher, M., …Achana, F. (2023). Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study. Current Medical Research and Opinion, 1-8. https://doi.org/10.1080/03007995.2023.2271862

Objective
To investigate the impact of pre-existing painful musculoskeletal conditions on healthcare utilization and costs among patients with five common conditions: acute coronary syndrome (ACS), stroke, cancer, dementia and pneumonia.

Methods... Read More about Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study.

Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review (2023)
Journal Article
Mudge, H. R., Honey, J. R., Tachoukaft, S., Hider, S. L., Mason, K. J., Welsh, V. K., & Burton, C. (in press). Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review. Arthritis Care & Research, 76(1), 40-48. https://doi.org/10.1002/acr.25227

Musculoskeletal symptoms are commonly reported following acute coronavirus disease 2019 (COVID‐19). It is unclear whether those with musculoskeletal symptoms subsequently develop inflammatory rheumatic musculoskeletal disease (iRMD). This review seek... Read More about Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review.

Psoriasis and COVID-19: findings from PsoProtectMe. (2023)
Conference Proceeding
McGrath, C., Yates, M., Yiu, Z., Langan, S., Tsakok, T., Dand, N., …Mahil, S. (2023). Psoriasis and COVID-19: findings from PsoProtectMe. . https://doi.org/10.55788/819f9152

POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY (2023)
Presentation / Conference
Bajpai, R., Burton, C., Mason, K., Bailey, J., Frisher, M., Jordan, K., …Welsh, V. (2023, May). POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY. Poster presented at EULAR 2023 European Congress of Rheumatology, Milan, Italy

Background Inflammatory rheumatic and musculoskeletal diseases (iRMDs), including rheumatoid arthritis (RA) and juveneille inflammatory arthritsi (JIA), are common and cause a high disease burden globally. Early diagnosis of iRMDs and subsequent time... Read More about POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY.

Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2023)
Journal Article
Alabas, O. A., Mason, K. J., Yiu, Z. Z. N., Warren, R. B., Lunt, M., Smith, C. H., …Zietemann, V. (2023). Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 189(3), 271–278. https://doi.org/10.1093/bjd/ljad179

Background
Most information on the comparative effectiveness and survival of methotrexate (MTX) and adalimumab (ADA) in the treatment of psoriasis is from randomized control trials and may not translate to the everyday clinical setting.

Objective... Read More about Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).