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Abstract 15368: Index Admission and Thirty-day Readmission Outcomes of Cancer Patients Presenting With Stemi (2020)
Journal Article
Osman, M., Benjamin, M. M., Balla, S., Kheiri, B., Bianco, C., sengupta, P., …Patel, B. (2020). Abstract 15368: Index Admission and Thirty-day Readmission Outcomes of Cancer Patients Presenting With Stemi. Circulation, 142(Suppl_3), https://doi.org/10.1161/circ.142.suppl_3.15368

Introduction: National-level data of cancer patients’ readmissions after a ST-segment elevation myocardial infarction (STEMI) are lacking. Objectives: The primary aim of this study was to describe rates and causes of 30-day readmissions in this po... Read More about Abstract 15368: Index Admission and Thirty-day Readmission Outcomes of Cancer Patients Presenting With Stemi.

Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018. (2020)
Journal Article
Mamas. (2020). Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, e017433 - ?. https://doi.org/10.1161/JAHA.120.017433

Background Aortic stenosis-related mortality might vary across demographic subsets, regions, and states in the United States. Methods and Results We reviewed the death certificate data from the Centers for Disease Control and Prevention Wide-Ranging... Read More about Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018..

Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. (2020)
Journal Article
Mamas, M. (2020). Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. https://doi.org/10.1002/ccd.29110

OBJECTIVES: We performed a systematic review and meta-analysis to evaluate the early and midterm outcomes of patients who underwent surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG) against patients who had transcath... Read More about Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis..

Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort. (2020)
Journal Article
Mamas. (2020). Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort. Circulation: Cardiovascular Interventions, e009654 - ?. https://doi.org/10.1161/CIRCINTERVENTIONS.120.009654

BACKGROUND: The objective of the study was to evaluate changes in percutaneous coronary intervention (PCI) practice in England by analyzing procedural numbers, changes in the clinical presentation, and characteristics of patients and their clinical o... Read More about Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort..

Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis. (2020)
Journal Article
Rashid, & Mamas. (2020). Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis. Journal of Cardiovascular Medicine, 897-904. https://doi.org/10.2459/JCM.0000000000001110

BACKGROUND: The management of patients with severe but asymptomatic aortic stenosis is challenging. Evidence on early aortic valve replacement (AVR) versus symptom-driven intervention in these patients is unknown. METHODS: Electronic databases were s... Read More about Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis..

Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis (2020)
Journal Article
Mamas. (2020). Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis. Expert Review of Cardiovascular Therapy, https://doi.org/10.1080/14779072.2021.1845143

Objectives: Intravascular lithotripsy (IVL) clinical efficacy and safety in the treatment of calcified coronary artery disease (CAC) is not well known. We sought to assess IVL safety and efficacy in CAC. Methods: A comprehensive online databases s... Read More about Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis.

Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes (2020)
Journal Article
Mohamed, M., Rashid, M., Farooq, S., Siddiqui, N., Parwani, P., Shiers, D., …Mamas, M. (2020). Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes. European Heart Journal, 41(Supplement_2), https://doi.org/10.1093/ehjci/ehaa946.3146

Background Severe mental illness (SMI) is associated with an increased risk of cardiovascular disease and mortality. However, it is unclear whether SMI patients are just as likely to receive guideline-recommended therapy for AMI as those without men... Read More about Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes.

Trends of sex differences in outcomes of cardiac electronic device implantations in the United States (2020)
Journal Article
Mohamed, M., Volgman, A., Contractor, T., Sharma, P., Kwok, C., Martin, G., …Mamas, M. (2020). Trends of sex differences in outcomes of cardiac electronic device implantations in the United States. European Heart Journal, 41(Supplement_2), https://doi.org/10.1093/ehjci/ehaa946.0831

Background There is limited evidence on the differences in procedural outcomes between sexes after de novo cardiac implantable electronic device implantation (CIED). Furthermore, it is unclear whether any sex-based disparities have changed over the... Read More about Trends of sex differences in outcomes of cardiac electronic device implantations in the United States.

Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors. (2020)
Journal Article
Mamas. (2020). Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors. Journal of the American College of Cardiology, 1919 - 1930. https://doi.org/10.1016/j.jacc.2020.08.062

BACKGROUND: Clinical trials change practice in cardiology, and leading them requires research training, mentorship, sponsorship, and networking. Women report challenges in obtaining these opportunities. OBJECTIVES: The purpose of this review was to e... Read More about Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors..

TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction (2020)
Journal Article
Panchal, H., Zheng, S., White, C., Leinaar, E., Mukherjee, D., Mamas, M., …Paul, T. (2020). TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 76(17), B18. https://doi.org/10.1016/j.jacc.2020.09.072

Background Chronic kidney disease (CKD) in patients with ST-segment elevation myocardial infarction (STEMI) has been associated with worse outcomes. Our study sought to assess the impact of CKD on guideline-directed coronary revascularization and ou... Read More about TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction.

TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States (2020)
Journal Article
Nagaraja, V., Rashid, M., Anderson, H., Ludman, P., Kapadia, S., Starling, R., …Mamas, M. (2020). TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States. Journal of the American College of Cardiology, 76(17), B109. https://doi.org/10.1016/j.jacc.2020.09.264

Background Five years after transplantation, coronary allograft vasculopathy and late graft failure account for 32% of all mortality. The current role of percutaneous coronary intervention (PCI) in coronary allograft vasculopathy is unclear and cons... Read More about TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States.

TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha (2020)
Journal Article
Alexander Menown, I. B., Mamas, M., Cotton, J., Hildick-Smith, D., Eberli, F., Leibundgut, G., …Oldroyd, K. (2020). TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha. Journal of the American College of Cardiology, 76(17), B116. https://doi.org/10.1016/j.jacc.2020.09.283

Background Thinner stent struts may improve deliverability and conformability and reduce vessel injury. The final clinical outcomes of the thinner strut (84 to 88 μm) cobalt chromium biolimus eluting stent from the BioMatrix (BMX) Alpha registry are... Read More about TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha.

Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality (2020)
Journal Article
Mohamed, M. O., Banerjee, A., Clarke, S., de Belder, M., Patwala, A., Goodwin, A. T., …Mamas, M. (2021). Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality. European Heart Journal - Quality of Care and Clinical Outcomes, 7(3), 247-256. https://doi.org/10.1093/ehjqcco/qcaa079

Background: Limited data exists on the impact of COVID-19 on national changes in cardiac procedure activity, including patient characteristics and clinical outcomes before and during the COVID-19 pandemic. Methods and Results: All major cardiac pr... Read More about Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality.

Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials (2020)
Journal Article
Mamas. (2020). Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials. Journal of the American College of Cardiology, 1919-1930. https://doi.org/10.1016/j.jacc.2020.08.062

Background Clinical trials change practice in cardiology, and leading them requires research training, mentorship, sponsorship, and networking. Women report challenges in obtaining these opportunities. Objectives The purpose of this review was t... Read More about Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials.

Excess mortality in England and Wales during the first wave of the COVID-19 pandemic. (2020)
Journal Article
Mamas. (2020). Excess mortality in England and Wales during the first wave of the COVID-19 pandemic. Journal of Epidemiology and Community Health, 213 - 223. https://doi.org/10.1136/jech-2020-214764

BACKGROUND: Deaths during the COVID-19 pandemic result directly from infection and exacerbation of other diseases and indirectly from deferment of care for other conditions, and are socially and geographically patterned. We quantified excess mortalit... Read More about Excess mortality in England and Wales during the first wave of the COVID-19 pandemic..

Impact of COVID19 Pandemic on the Incidence and Management of Out of Hospital Cardiac Arrest in Patients Presenting with Acute Myocardial Infarction in England (2020)
Journal Article
Rashid, M., Gale, C. P., Curzen, N., Ludman, P., De Belder, M., Timmis, A., …Mamas, M. (2020). Impact of COVID19 Pandemic on the Incidence and Management of Out of Hospital Cardiac Arrest in Patients Presenting with Acute Myocardial Infarction in England. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 9(22), https://doi.org/10.1161/JAHA.120.018379

Background: Studies have reported significant reduction in acute myocardial infarction (AMI) related hospitalizations during the COVID19 pandemic. However, whether these trends are associated with increased incidence of Out of Hospital Cardiac Arrest... Read More about Impact of COVID19 Pandemic on the Incidence and Management of Out of Hospital Cardiac Arrest in Patients Presenting with Acute Myocardial Infarction in England.

Seasonality of stroke: Winter admissions and mortality excess: A Thailand National Stroke population database study. (2020)
Journal Article
Lorking, N., Wood, A. D., Tiamkao, S., Clark, A. B., Kongbunkiat, K., Bettencourt-Silva, J. H., …Myint, P. K. (2020). Seasonality of stroke: Winter admissions and mortality excess: A Thailand National Stroke population database study. Clinical Neurology and Neurosurgery, 106261 - ?. https://doi.org/10.1016/j.clineuro.2020.106261

OBJECTIVES: We examined the existence and potential burden of seasonality of stroke admissions and mortality within a tropical climate using cohort data collected between 1?st November 2003 and 31?st October 2012. PATIENTS AND METHODS: In a prospecti... Read More about Seasonality of stroke: Winter admissions and mortality excess: A Thailand National Stroke population database study..

Meta-Analysis Comparing the Safety and Efficacy of Prasugrel and Ticagrelor in Acute Coronary Syndrome. (2020)
Journal Article
Mamas. (2020). Meta-Analysis Comparing the Safety and Efficacy of Prasugrel and Ticagrelor in Acute Coronary Syndrome. American Journal of Cardiology, 22 - 28. https://doi.org/10.1016/j.amjcard.2020.07.017

Prasugrel and ticagrelor are preferred over clopidogrel for patients with acute coronary syndrome who underwent percutaneous coronary intervention. We sought to determine the relative merits of 1 agent over the other. Multiple databases were queried... Read More about Meta-Analysis Comparing the Safety and Efficacy of Prasugrel and Ticagrelor in Acute Coronary Syndrome..