All Outputs (991)

Combination of Suture‐Plug Vascular Closure Devices Versus Suture‐Only Devices Following Transcatheter Aortic Valve Implantation: A Systematic Review and Meta‐Analysis (2025)
Journal Article
Haddad, S., Bashour, G., & Mamas, M. A. (2025). Combination of Suture‐Plug Vascular Closure Devices Versus Suture‐Only Devices Following Transcatheter Aortic Valve Implantation: A Systematic Review and Meta‐Analysis. Catheterization and Cardiovascular Interventions, 1-10. https://doi.org/10.1002/ccd.31655

ABSTRACT
Background
Transcatheter aortic valve implantation (TAVI) is an effective and safe intervention for severe symptomatic aortic stenosis regardless of surgical risk. Vascular complications following TAVI are considered among the most common... Read More about Combination of Suture‐Plug Vascular Closure Devices Versus Suture‐Only Devices Following Transcatheter Aortic Valve Implantation: A Systematic Review and Meta‐Analysis.

Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline. (2025)
Journal Article
Lamelas, P., Pompeu Sá, M., Izcovich, A., Bottaro, F., Tisi Baña, M., Sosa Liprandi, M. I., Lanas, F., Vilca Mejia, O. A., Zuñiga Luna, M., Aubanel, P., Munera, A., Contreras Reyes, J., Bagur, R., Whitlock, R., Garcia Garcia, H., Mamas, M., Cohen, M. G., Ricalde, A., Abizaid, A., Mendiz, O., …Ragusa, M. A. (2025). Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline. International Journal of Cardiology, 436(1 October 2025), Article 133401. https://doi.org/10.1016/j.ijcard.2025.133401

Severe left main coronary artery disease (LMD) poses a major treatment challenge in Latin America, where both percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are used. This guideline was developed de novo using the... Read More about Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline..

Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper (2025)
Journal Article
Escaned, J., Lombardi, M., Götberg, M., Amabile, N., Banning, A., Barbato, E., Brugaletta, S., Chen, S.-L., Doshi, D., Koo, B.-K., Kozuma, K., Mahadevan, K., Milasinovic, D., Sinning, J.-M., Toth, G., Gonzalo, N., Mamas, M. A., & Kirtane, A. J. (2025). Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper. Journal of the Society for Cardiovascular Angiography & Interventions, 103607. https://doi.org/10.1016/j.jscai.2025.103607

Intracoronary imaging (ICI) was introduced over 3 decades ago to complement conventional coronary angiography, yet its widespread uptake remains limited. This paper seeks to explore the potential causes behind low ICI utilization. The concepts of acc... Read More about Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper.

Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease. (2025)
Journal Article
Abomoawad, A., Sedhom, R., Golwala, H., Abdelazeem, M., Mamas, M., Jneid, H., Bavry, A. A., Kumbhani, D. J., Kapadia, S., & Elbadawi, A. (2025). Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease. Cardiology and Therapy, https://doi.org/10.1007/s40119-025-00415-7

There is a paucity of data regarding the trends and comparative outcomes of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) among patients with polyvascular disease (PVD). The Nationwide Readmissions Data... Read More about Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease..

Predicting mortality risk using the PREVENT equation across diverse racial groups. (2025)
Journal Article
Kobo, O., Rutter, M. K., Misra, S., Michos, E. D., Myint, P. K., Roguin, A., Sun, L. Y., & Mamas, M. A. (2025). Predicting mortality risk using the PREVENT equation across diverse racial groups. American Journal of Managed Care, 31(5), e113-e119. https://doi.org/10.37765/ajmc.2025.89734

The Predicting Risk of CVD Events (PREVENT) score offers a contemporary tool for assessing cardiovascular risk without incorporating race, which has raised concerns about its performance across diverse racial and ethnic groups. We aimed to validate t... Read More about Predicting mortality risk using the PREVENT equation across diverse racial groups..

Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database. (2025)
Journal Article
Castaldi, G., Matetić, A., Bagur, R., Abbott, J. D., Alasnag, M., Chieffo, A., Wijeysundera, H. C., & Mamas, M. A. (2025). Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database. Journal of the American Heart Association, 14(10), Article e038463. https://doi.org/10.1161/JAHA.124.038463

Referral for valve intervention for severe aortic stenosis (AS) may exhibit sex-associated disparities independent of the growth of transcatheter interventions. This study aimed to determine whether there were sex-associated differences in the use of... Read More about Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database..

Impact of obesity on clinical outcomes in patients with high-risk pulmonary embolism: A comparative analysis. (2025)
Journal Article
Shachar, Z., Gatuz, M. V., Folman, A., Barel, M. S., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (2025). Impact of obesity on clinical outcomes in patients with high-risk pulmonary embolism: A comparative analysis. International Journal of Cardiology, 58, 101682. https://doi.org/10.1016/j.ijcha.2025.101682

Pulmonary embolism (PE) is a life-threatening cardiovascular condition with increasing global incidence. Obesity is a significant risk factor for PE, although its reported relationship with outcomes is inconsistent. This study aimed to investigate th... Read More about Impact of obesity on clinical outcomes in patients with high-risk pulmonary embolism: A comparative analysis..

Location of Terminal Care in Pulmonary Hypertension (2025)
Journal Article
Ibrahim, R., Habib, A., Olson, A., Shrourou, F., Pham, H. N., Abdelnabi, M., Neyestanak, M. E., Soin, S., Low, S.-W., Natt, B., Mamas, M. A., Barry, T., Ayoub, C., Arsanjani, R., Rischard, F. P., & Lee, K. (2025). Location of Terminal Care in Pulmonary Hypertension. CJC Open, 7(6), 832-839. https://doi.org/10.1016/j.cjco.2025.03.026

Background
Death locations for individuals in the US is influenced by social factors. Pulmonary hypertension (PH) is an uncommon condition, with a substantial impact on morbidity and mortality. We evaluated the patterns in and impact of demographics... Read More about Location of Terminal Care in Pulmonary Hypertension.

Why and how academic medicine must champion diversity, equity, inclusion, and accessibility. (2025)
Journal Article
Salles, A., Banerjee, A. T., Caceres, W., Mamas, M., & Blackstock, O. (2025). Why and how academic medicine must champion diversity, equity, inclusion, and accessibility. The Lancet, 1-4. https://doi.org/10.1016/S0140-6736%2825%2900575-6

Impact of Socioeconomic Disparities on Care and Outcomes of Cancer Patients Presenting With STEMI Between 2005 and 2019; a Nationwide British Study (2025)
Journal Article
Dafaalla, M., Weight, N., Rashid, M., Nolan, J., & Mamas, M. A. (2025). Impact of Socioeconomic Disparities on Care and Outcomes of Cancer Patients Presenting With STEMI Between 2005 and 2019; a Nationwide British Study. Clinical Cardiology, 48(4), Article e70135. https://doi.org/10.1002/clc.70135

Background: While current evidence suggests that the clinical outcomes of STEMI are worse among patients with cancer, it is unknown what role the patient's socioeconomic status plays. Methods: A nationally linked cohort of STEMI patients (January 200... Read More about Impact of Socioeconomic Disparities on Care and Outcomes of Cancer Patients Presenting With STEMI Between 2005 and 2019; a Nationwide British Study.

Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients (2025)
Journal Article
Shabtai, R., Gatuz, M. V., Folman, A., Barel, M. S., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (in press). Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients. Diseases, 13(4), 97. https://doi.org/10.3390/diseases13040097

Background: Cardiovascular–kidney–metabolic (CKM) syndrome, recently defined by the American Heart Association, encompasses the interplay between obesity, diabetes, chronic kidney disease, and cardiovascular disease. This study aimed to investigate t... Read More about Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients.

Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials (2025)
Journal Article
Ahmed, M., Ahsan, A., Shafiq, A., Hashmi, T. M., Ahmed, R., Alam, M., Shahid, F., Rana, J. S., Mamas, M. A., & Fonarow, G. C. (in press). Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials. Journal of the American Geriatrics Society, https://doi.org/10.1111/jgs.19447

Background: Non‐ST segment elevation acute coronary syndromes (NSTE‐ACS) are a common cause of hospital admission in older patients. Our study aims to synthesize the available evidence from randomized controlled trials (RCTs) to compare clinical outc... Read More about Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials.

Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population (2025)
Journal Article
Szabo, L., Cooper, J., Condurache, D.-G., Dostal, I., Andriamiadana, G., Mathur, R., Walter, F. M., Mamas, M. A., Manisty, C. H., Harvey, N. C., Neubauer, S., Petersen, S. E., Robson, J., & Raisi-Estabragh, Z. (2025). Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population. Heart, https://doi.org/10.1136/heartjnl-2024-325309

Background: Cardiovascular disease (CVD) burden and risk factor management among cancer survivors, especially in socioeconomically deprived, multiethnic populations, remain understudied. This study examines CVD burden and risk factor control in survi... Read More about Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population.

Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study (2025)
Journal Article
Cole, A., Weight, N., Wijeysundera, H. C., Rashid, M., Yu, D., Healey, E. L., Chew, N. W., Siudak, Z., Khunti, K., Kontopantelis, E., & Mamas, M. A. (in press). Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study. Diabetes Research and Clinical Practice, 222, 1-10. https://doi.org/10.1016/j.diabres.2025.112092

This study aimed to assess how diabetes influences the quality of care and longer-term outcomes in contemporary STEMI cohorts. We analysed 283,658 adults hospitalised with STEMI from the United Kingdom Myocardial Ischaemia National Audit Project (MIN... Read More about Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study.

Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. (2025)
Journal Article
Ryan, M., Petrie, M. C., Kontopantelis, E., Dodd, M., Tong, G., Marquis-Gravel, G., Docherty, K. F., Clayton, T., Lansky, A. J., Mamas, M. A., Rouleau, J.-L., Velazquez, E. J., & Perera, D. (in press). Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. European Heart Journal, 1-11. https://doi.org/10.1093/eurheartj/ehaf080

In the Surgical Treatment for Ischaemic Heart Failure Trial Extension Study (STICHES), coronary artery bypass grafting (CABG) improved outcomes of patients with ischaemic left ventricular dysfunction receiving medical therapy, whereas in the Revascul... Read More about Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis..

Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer (2025)
Journal Article
Dafaalla, M., Walter Dhillon Shanmuganathan, J., Wijeysundera, H. C., Roberts, D. J., Khan, S. U., Elbadawi, A., Elgendy, I. Y., Freeman, P., Mallen, C., & Mamas, M. A. (in press). Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcaf004

Background While current evidence suggests that the clinical outcomes of ST-elevation myocardial infarction (STEMI) are worse among patients with cancer, it is unknown what role the quality of care received during admission plays. We aimed to evaluat... Read More about Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer.

Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative. (2025)
Journal Article
Cheng, R. K., Roberts, M. B., Bansal, N., Reding, K., Salahuddin, T., Mamas, M., LaMonte, M., Shadyab, A. H., Franceschini, N., Klein, L., Manson, J. E., & Eaton, C. B. (in press). Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative. Journal of the American Heart Association, 14(5), Article e037051. https://doi.org/10.1161/JAHA.124.037051

Studies have shown an association of chronic kidney disease with heart failure (HF); however, this association has not been adequately examined in postmenopausal women, who are at heightened risk of both chronic kidney disease and HF. Additionally, a... Read More about Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative..

Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases. (2025)
Journal Article
Gatuz, M. V., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (2025). Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases. IJC Heart & Vasculature, 57, Article 101637. https://doi.org/10.1016/j.ijcha.2025.101637

Pulmonary embolism (PE) is a critical condition with significant morbidity and mortality, particularly among patients with chronic inflammatory diseases (CID) such as rheumatoid arthritis and systemic lupus erythematosus that are linked to a heighten... Read More about Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases..

Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. (2025)
Journal Article
Williams, M. M., Smith, N. R., Uyl-de Groot, C. A., den Uil, C. A., Ross, J. S., Mohamed, M. O., Mamas, M. A., Banerjee, A., Ko, D. T., Landon, B., & Cram, P. (in press). Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. Circulation: Cardiovascular Quality and Outcomes, Article e011636. https://doi.org/10.1161/CIRCOUTCOMES.124.011636

The authorization process and coverage/reimbursement mechanisms for medical devices play critical roles in device adoption and usage. However, international variation in these processes remains poorly characterized, especially with regard to data tra... Read More about Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries..

Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk. (2025)
Journal Article
Gray, R., Manisty, C., Cheng, R., Dastidar, A., Mamas, M., & Ghosh, A. (in press). Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk. Atherosclerosis, 403, Article 119147. https://doi.org/10.1016/j.atherosclerosis.2025.119147

1. Introduction
The development of immune checkpoint inhibitors (ICI) has transformed the landscape of cancer treatment in the past decade with these agents becoming the standard of care in the treatment of many malignancies [1]. There are currently... Read More about Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk..