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Trends in Peritoneal Dialysis Technique Survival, Death, and Transfer to Hemodialysis: A Decade of Data from the RDPLF (2021)
Journal Article
Boyer, A., Lanot, A., Lambie, M., Verger, C., Guillouet, S., Lobbedez, T., & Béchade, C. (2021). Trends in Peritoneal Dialysis Technique Survival, Death, and Transfer to Hemodialysis: A Decade of Data from the RDPLF. American Journal of Nephrology, 52(4), 318-327. https://doi.org/10.1159/000515472

There is limited information on the trends of peritoneal dialysis (PD) technique survival over time. This study aimed to estimate the effect of calendar time on technique survival, transfer to hemodialysis (HD) (and the individual causes of transfer... Read More about Trends in Peritoneal Dialysis Technique Survival, Death, and Transfer to Hemodialysis: A Decade of Data from the RDPLF.

Outcome measures for technique survival reported in peritoneal dialysis: A systematic review. (2021)
Journal Article
Lambie, & Davies. (2021). Outcome measures for technique survival reported in peritoneal dialysis: A systematic review. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/0896860821989874

BACKGROUND: Peritoneal dialysis (PD) technique survival is an important outcome for patients, caregivers and health professionals, however, the definition and measures used for technique survival vary. We aimed to assess the scope and consistency of... Read More about Outcome measures for technique survival reported in peritoneal dialysis: A systematic review..

ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention. (2021)
Journal Article
Davies, & Lambie. (2021). ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 352-372. https://doi.org/10.1177/0896860820982218

GUIDELINE 1: A pathophysiological taxonomy: A pathophysiological classification of membrane dysfunction, which provides mechanistic links to functional characteristics, should be used when prescribing individualized dialysis or when planning modality... Read More about ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention..

How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. (2020)
Journal Article
Allen, K., Damery, S. L., Sein, K., Johnson, D. W., Davies, S. J., Lambie, M., …Combes, G. M. (2020). How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 42(3), https://doi.org/10.1177/0896860820975596

BACKGROUND: While numerous studies have explored the patient experience of dialysis or other end-stage kidney disease (ESKD) treatments, few have explored the process of transitioning between dialysis modalities. This study aimed to develop an in-dep... Read More about How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia..

Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. (2020)
Journal Article
Lambie. (2020). Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. Clinical Kidney Journal, 1003 - 1011. https://doi.org/10.1093/ckj/sfaa051

Background: There is limited information available on the use of assisted peritoneal dialysis (PD) over time and the impact of economic incentives on its utilization. The aim of this study was to describe the trends in assisted PD utilization and the... Read More about Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry..

The osmo-metabolic approach: a novel and tantalizing glucose-sparing strategy in peritoneal dialysis. (2020)
Journal Article
Bonomini, M., Zammit, V., Divino-Filho, J. C., Davies, S. J., Di Liberato, L., Arduini, A., & Lambie, M. (2020). The osmo-metabolic approach: a novel and tantalizing glucose-sparing strategy in peritoneal dialysis. Journal of Nephrology, 34, Article 503–519. https://doi.org/10.1007/s40620-020-00804-2

Peritoneal dialysis (PD) is a viable but under-prescribed treatment for uremic patients. Concerns about its use include the bio-incompatibility of PD fluids, due to their potential for altering the functional and anatomical integrity of the peritonea... Read More about The osmo-metabolic approach: a novel and tantalizing glucose-sparing strategy in peritoneal dialysis..

Nomenclature for Kidney Function and Disease: Report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference (2020)
Journal Article
Lambie. (2020). Nomenclature for Kidney Function and Disease: Report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference. Kidney International, 1117-1129. https://doi.org/10.1016/j.kint.2020.02.010

The worldwide burden of kidney disease is rising, but public awareness remains limited, underscoring the need for more effective communication by stakeholders in the kidney health community. Despite this need for clarity, the nomenclature for describ... Read More about Nomenclature for Kidney Function and Disease: Report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.

Establishing a Core Outcome Set for Peritoneal Dialysis: Report of the SONG-PD (Standardized Outcomes in Nephrology–Peritoneal Dialysis) Consensus Workshop (2020)
Journal Article
Manera, K. E., Johnson, D. W., Craig, J. C., Shen, J. I., Gutman, T., Cho, Y., …Butt, Z. (2020). Establishing a Core Outcome Set for Peritoneal Dialysis: Report of the SONG-PD (Standardized Outcomes in Nephrology–Peritoneal Dialysis) Consensus Workshop. American Journal of Kidney Diseases, 75(3), 404-412. https://doi.org/10.1053/j.ajkd.2019.09.017

Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation (2020)
Journal Article
Boyer, A., Solis-Trapala, I., Tabinor, M., Lambie, M., & Davies, S. (2020). Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation. Nephrology Dialysis Transplantation, 35(9), 1595-1601. https://doi.org/10.1093/ndt/gfz287

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>There is limited information available on the impact that provision of an assisted peritoneal dialysis (PD) service has on the initiation of PD. The aim of this... Read More about Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation.

How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies (2019)
Journal Article
Barrowman, M. A., Peek, N., Lambie, M., Martin, G. P., & Sperrin, M. (2019). How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies. BMC medical research methodology, 19, Article 166. https://doi.org/10.1186/s12874-019-0808-7

Background
Analysis of competing risks is commonly achieved through a cause specific or a subdistribution framework using Cox or Fine & Gray models, respectively. The estimation of treatment effects in observational data is prone to unmeasured confo... Read More about How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies.

Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir? (2019)
Journal Article
Shen, J. I., Schreiber, M. J., Zhao, J., Robinson, B. M., Pisoni, R. L., Mehrotra, R., …Perl, J. (2019). Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir?. Clinical Journal of the American Society of Nephrology, 14(7), 1067-1070. https://doi.org/10.2215/CJN.01320119

Research letter.

Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018) (2019)
Journal Article
Davies, & Lambie. (2019). Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018). Clinical Journal of the American Society of Nephrology, 909 - 909. https://doi.org/10.2215/CJN.02830319

Background and objectives: The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bio... Read More about Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018).

Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death (2019)
Journal Article
Lambie, M., Teece, L., Johnson, D. W., Petrie, M., Mactier, R., Solis-Trapala, I., …Davies, S. J. (2019). Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death. Nephrology Dialysis Transplantation, 1585-1591. https://doi.org/10.1093/ndt/gfz034

Background
Risk of Encapsulating Peritoneal Sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate risk o... Read More about Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients (2019)
Journal Article
Yu, Z., Lambie, M., Chess, J., Williams, A., Do, J., Topley, N., & Davies, S. J. (2019). Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients. Frontiers in Physiology, 10, 105 -105. https://doi.org/10.3389/fphys.2019.00105

It is not clear whether the association of increased peritoneal protein clearance with worse survival on PD is a consequence of either local or systemic inflammation or indicative of generalized endothelial dysfunction associated with comorbidity. To... Read More about Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients.

Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative (2019)
Journal Article
Chan, C., Combes, G., Davies, S., Finkelstein, F., Firanek, C., Gomez, R., …Van Biesen, W. (2019). Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 39(1), 4 -12. https://doi.org/10.3747/pdi.2017.00242

Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The "integrated care" model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such... Read More about Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.

Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport (2018)
Journal Article
Davies, & Lambie. (2018). Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport. Clinical Journal of the American Society of Nephrology, 1526-1533. https://doi.org/10.2215/%3FCJN.02380218

Background and objectives
The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bio... Read More about Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport.

Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport (2018)
Journal Article
Elphick, E. H., Teece, L., Chess, J. A., Do, J., Kim, Y., Lee, H. B., …Lambie, M. (2018). Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport. Clinical Journal of the American Society of Nephrology, 13(10), 1526-1533. https://doi.org/10.2215/cjn.02380218

Background and objectives
The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bi... Read More about Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport.

FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS (2018)
Journal Article
Brenna, I., Elphick, E., Lambie, M., & Davies, S. (2018). FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS. Nephrology Dialysis Transplantation, 33(suppl_1), i194-i194. https://doi.org/10.1093/ndt/gfy104.fp467

INTRODUCTION AND AIMS: Long term peritoneal dialysis (PD) is associated with increased peritoneal solute transport rate (PSTR), which correlates with hard outcomes. Whether different clinical approaches affect PSTR rate of increase is unclear.

MET... Read More about FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS.

Bioimpedance-defined overhydration predicts survival in end stage kidney failure (ESKF): systematic review and subgroup meta-analysis. (2018)
Journal Article
Tabinor, M., Elphick, E., Dudson, M., Shing Kwok, C., Lambie, M., & Davies, S. J. (2018). Bioimpedance-defined overhydration predicts survival in end stage kidney failure (ESKF): systematic review and subgroup meta-analysis. Scientific reports, 8, Article 4441. https://doi.org/10.1038/s41598-018-21226-y

Both overhydration and comorbidity predict mortality in end-stage kidney failure (ESKF) but it is not clear whether these are independent of one another. We undertook a systematic review of studies reporting outcomes in adult dialysis patients in whi... Read More about Bioimpedance-defined overhydration predicts survival in end stage kidney failure (ESKF): systematic review and subgroup meta-analysis..