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Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses (2024)
Journal Article
Chien, M., Huang, C., Wang, J., Shih, C., & Wu, P. (in press). Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses. Nutrition and Diabetes, 14(1), Article 35. https://doi.org/10.1038/s41387-024-00296-0

Background: Vitamin D deficiency has been linked with several adverse maternal and fetal outcomes. Objective: To summarize systematic reviews and meta-analyses evaluating the effects of vitamin D deficiency and of vitamin D supplementation in pregnan... Read More about Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses.

Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis (2024)
Journal Article
Walters, B., Midwinter, I., A. Chew-Graham, C., P. Jordan, K., Sharma, G., C. Chappell, L., …Wu, P. (2024). Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis. Mayo Clinic Proceedings, 8(2), 188-199. https://doi.org/10.1016/j.mayocpiqo.2024.02.002

This study aimed to systematically evaluate and quantify the risk of adverse maternal and neonatal outcomes in patients with pregnancy-associated cancer (PAC). This study was conducted from February 13, 2021, through July 24, 2023.... Read More about Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis.

Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis (2024)
Journal Article
Jeyaraman, D., Walters, B., Bramham, K., Fish, R., Lambie, M., & Wu, P. (2024). Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis. BJOG: An International Journal of Obstetrics and Gynaecology, https://doi.org/10.1111/1471-0528.17807

Background Chronic kidney disease (CKD) is associated with an increased risk of adverse pregnancy outcomes, but the risk at different stages of CKD (defined by estimated glomerular filtration rate, eGFR) compared with women without CKD has not been... Read More about Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis.

Correction to: Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion (2023)
Journal Article
Holland, D., A. Fryer, A., Stedman, M., W. F. Hanna, F., J. Duff, C., Green, L., …Wu, P. (2023). Correction to: Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion. Diabetes Therapy, https://doi.org/10.1007/s13300-023-01498-y

Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations] (2023)
Journal Article
Maher, G. M., Kenny, L. C., Navaratnam, K., Alfirevic, Z., Sheehan, D., Baker, P. N., …Khashan, A. S. (2023). Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations]. HRB Open Research, 6(65), https://doi.org/10.12688/hrbopenres.13812.1

Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the assessment and refinement of innovative prototype preeclampsia risk assessment t... Read More about Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations].

Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion (2023)
Journal Article
Holland, D., Fryer, A. A., Stedman, M., Hanna, F. W. F., Duff, C. J., Green, L., …Wu, P. (2023). Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion. Diabetes Therapy, https://doi.org/10.1007/s13300-023-01482-6

Women are on average diagnosed with diabetes mellitus at later age than men but have higher mortality. As the diagnosis of diabetes mellitus is primarily based on HbA1c, the use of a non-specific reference range and cut point for diabetes mellitus th... Read More about Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion.

Substance Use in Pregnancy and its Association With Cardiovascular Events (2023)
Journal Article
Evans, K., Wu, P., Mamas, M. A., Irwin, C., Kang, P., Perlow, J. H., …Gulati, M. (2023). Substance Use in Pregnancy and its Association With Cardiovascular Events. JACC: Advances, 2(8), 100619. https://doi.org/10.1016/j.jacadv.2023.100619

Background Substance use and cardiovascular (CV) events are increasing among pregnant women in the United States, but association between substance use in pregnancy and CV events remains unknown. Objectives The purpose of this stu... Read More about Substance Use in Pregnancy and its Association With Cardiovascular Events.

Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome (2023)
Journal Article
Hanna, F., Wu, P., Heald, A., & Fryer, A. (2023). Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome. BMJ, 382, Article e071675. https://doi.org/10.1136/bmj-2022-071675

Gestational diabetes mellitus (GDM) and polycystic ovarian syndrome (PCOS) represent two of the highest risk factors for development of type 2 diabetes mellitus in young women. As these increasingly common conditions generally affect younger women, e... Read More about Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome.

Hypertensive disorders of pregnancy. (2023)
Journal Article
Wu, P., Green, M., & Myers, J. (2023). Hypertensive disorders of pregnancy. BMJ, 381, Article e071653. https://doi.org/10.1136/bmj-2022-071653

Hypertensive disorders of pregnancy (HDP) are one of the most commonly occurring complications of pregnancy and include chronic hypertension, gestational hypertension, and pre-eclampsia. New developments in early pregnancy screening to identify women... Read More about Hypertensive disorders of pregnancy..

The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation (2023)
Journal Article
Holland, D., Heald, A. H., Hanna, F. F., Stedman, M., Wu, P., Sim, J., …Fryer, A. A. (2023). The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation. Diabetes Therapy, 14, 691-707. https://doi.org/10.1007/s13300-023-01380-x

INTRODUCTION: Studies show that the COVID-19 pandemic disproportionately affected people with diabetes and those from disadvantaged backgrounds. During the first 6 months of the UK lockdown,?>?6.6 M glycated haemoglobin (HbA1c) tests were missed. We... Read More about The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation.

Home blood pressure monitoring detects unrevealed hypertension in women with a history of preeclampsia: Results of the BP-PRESELF study. (2022)
Journal Article
Muijsers, H. E., Wu, P., van der Heijden, O. W., Wijnberger, L. D., van Bijsterveldt, C., Buijs, C., …Maas, A. H. (2022). Home blood pressure monitoring detects unrevealed hypertension in women with a history of preeclampsia: Results of the BP-PRESELF study. American Journal of Preventive Cardiology, 100429 - ?. https://doi.org/10.1016/j.ajpc.2022.100429

OBJECTIVES: The risk of cardiovascular disease more than doubles after hypertensive disorders of pregnancy. As early onset chronic hypertension contributes to cardiovascular risk, implementation of screening strategies, using home blood pressure moni... Read More about Home blood pressure monitoring detects unrevealed hypertension in women with a history of preeclampsia: Results of the BP-PRESELF study..

Health Care Professional's Knowledge of Pregnancy Complications and Women's Cardiovascular Health: An International Study Utilizing Social Media (2022)
Journal Article
Wu, P., Mamas, M. A., & Gulati, M. (2022). Health Care Professional's Knowledge of Pregnancy Complications and Women's Cardiovascular Health: An International Study Utilizing Social Media. Journal of Women's Health, https://doi.org/10.1089/jwh.2021.0298

Background Despite guidelines recommending the evaluation of adverse pregnancy outcomes (APOs) as a part of the atherosclerotic cardiovascular disease (ASCVD) risk assessment in women, there is limited awareness of this issue in healthcare professio... Read More about Health Care Professional's Knowledge of Pregnancy Complications and Women's Cardiovascular Health: An International Study Utilizing Social Media.

Timing of induction of labour in the prevention of prolonged pregnancy: Systematic review with meta‐analysis (2022)
Journal Article
J. Geneen, L., Gilbert, J., Reeves, T., Mainie, P., Maresh, M., Smith, L., …Parisaei, M. (2022). Timing of induction of labour in the prevention of prolonged pregnancy: Systematic review with meta‐analysis. Reproductive, Female and Child Health, 1(1), 69-79. https://doi.org/10.1002/rfc2.6

Objective To update the systematic review which informed the National Institute for Health and Care Excellence guideline “Inducing Labour” (NG207), including additional data and analyses, and comparison with a recent individual patient data analysis... Read More about Timing of induction of labour in the prevention of prolonged pregnancy: Systematic review with meta‐analysis.

Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort (2022)
Journal Article
Wu, Mamas, Kwapong, Y. A., Boakye, E., Wang, G., Hong, X., …Sharma, G. (2022). Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort. Journal of Cardiovascular Development and Disease, 9(6), Article ARTN 179. https://doi.org/10.3390/jcdd9060179

Diabetes mellitus (pregestational (PDM) and gestational (GDM)) is associated with adverse pregnancy outcomes (APOs). However, studies exploring the association of APOs with maternal glycemia among women without PDM/GDM are limited. We utilized data f... Read More about Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort.

Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time (2022)
Journal Article
Fryer, A. A., Holland, D., Stedman, M., Duff, C. J., Green, L., Scargill, J., …Heald, A. H. (2022). Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time. Journal of Diabetes Research, 2022, 1 - 11. https://doi.org/10.1155/2022/7093707

Aims. We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c (delta HbA1c). Materials & Metho... Read More about Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time.

In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology (2022)
Journal Article
Wu, P., V. Sharma, G., S. Mehta, L., Chew-Graham, C., P. Lundberg, G., A. Nerenberg, K., …A. Mamas, M. (2022). In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology. Journal of the American Heart Association, 11(5), Article ARTN e022658. https://doi.org/10.1161/JAHA.121.022658

Background Assisted reproductive technology (ART) has emerged as a common treatment option for infertility, a problem that affects an estimated 48 million couples worldwide. Advancing maternal age with increasing prepregnancy cardiovascular risk fact... Read More about In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology.

The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States (2022)
Journal Article
Rashid, Mamas, & Wu. (2022). The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States. Mayo Clinic Proceedings, 88-100. https://doi.org/10.1016/j.mayocp.2021.06.029

Objective To investigate the utility of Charlson comorbidity index (CCI) as a measure of comorbidity burden to predict procedural outcomes after de novo cardiac implantable electronic device (CIED) implantation. Methods All de novo CIED implantati... Read More about The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States.

The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States (2021)
Journal Article
Mohamed, M. O., Van Spall, H. G., Morillo, C., Wilton, S. B., Kontopantelis, E., Rashid, M., …Mamas, M. (2022). The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States. Mayo Clinic Proceedings, 97(1), 88 - 100. https://doi.org/10.1016/j.mayocp.2021.06.029

OBJECTIVE: To investigate the utility of Charlson comorbidity index (CCI) as a measure of comorbidity burden to predict procedural outcomes after de novo cardiac implantable electronic device (CIED) implantation. METHODS: All de novo CIED implantatio... Read More about The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States.