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All Outputs (83)

Academic psychiatry is everyone's business. (2024)
Journal Article
Critchley, H. D., Tracy, D. K., Malhi, G. S., Alexander, L., Baldwin, D. S., Cavanagh, J., …Young, A. H. (in press). Academic psychiatry is everyone's business. British Journal of Psychiatry, 1-5. https://doi.org/10.1192/bjp.2024.152

This editorial considers the value and nature of academic psychiatry by asking what defines the specialty and psychiatrists as academics. We frame academic psychiatry as a way of thinking that benefits clinical services and discuss how to inspire the... Read More about Academic psychiatry is everyone's business..

Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study (2024)
Journal Article
Fisher, T., Chew‐Graham, C. A., Corp, N., Farooq, S., Kingston, P., Read, I., …Kingstone, T. (2024). Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study. Health Expectations, 27(5), Article e70028. https://doi.org/10.1111/hex.70028

Introduction: Anxiety and depression in older adults (60+ years of age) are under‐diagnosed and under‐treated. Older adults are less likely to seek help for these problems due to a lack of awareness, difficulty accessing health care due to availabili... Read More about Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study.

Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT) (2024)
Journal Article
Farooq, S., Hattle, M., Kingstone, T., Ajnakina, O., Dazzan, P., Demjaha, A., …Riley, R. D. (2024). Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT). British Journal of Psychiatry, 1-10. https://doi.org/10.1192/bjp.2024.101

Background
A clinical tool to estimate the risk of treatment-resistant schizophrenia (TRS) in people with first-episode psychosis (FEP) would inform early detection of TRS and overcome the delay of up to 5 years in starting TRS medication.

Aims... Read More about Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT).

Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot. (2024)
Journal Article
Fonseka, N., Khan, Z., Lewis, M., Kibria, Z., Ahmad, F., Khan, M. F., …Farooq, S. (2024). Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot. BMJ Open, 14(6), Article e083483. https://doi.org/10.1136/bmjopen-2023-083483

Introduction and objectivesThere is an unmet need to develop high-quality evidence addressing tuberculosis (TB)-related mental health comorbidity, particularly in the context of lower-middle-income countries. This study aims to examine the effectiven... Read More about Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot..

Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review (2024)
Journal Article
Farooq, S., Fonseka, N., Wajid Ali, M., Milner, A., Hamid, S., Sheikh, S., …Ayub, M. (2024). Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review. Schizophrenia Bulletin, Article sbae025. https://doi.org/10.1093/schbul/sbae025

Background and Hypothesis People with first-episode psychosis (FEP) in low- and lower-middle-income countries (LMIC) experience delays in receiving treatment, resulting in poorer outcomes and higher mortality. There is robust evidence for effective a... Read More about Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

The acceptability of the Fire and Rescue Service working with primary care to improve identification of mental health problems in older adults. A mixed-method qualitative study (2023)
Journal Article
Fisher, T., Chew-Graham, C. A., Corp, N., Farooq, S., Kingston, P., Read, I., …Kingstone, T. (2023). The acceptability of the Fire and Rescue Service working with primary care to improve identification of mental health problems in older adults. A mixed-method qualitative study. British Journal of General Practice Open (BJGP Open), 7(4), Article 0059. https://doi.org/10.3399/bjgpo.2023.0059

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), Article e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untrea... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives: In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untre... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review (2023)
Journal Article
Khan, M. F., Ul-Haq, Z., Ul Haq, M. M., Afridi, A., & Farooq, S. (2023). Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review. Pakistan Journal of Medical Sciences, 39(4), https://doi.org/10.12669/pjms.39.4.7286

Many people with Schizophrenia lack the resources and access to mental health services especially in low and middle income countries. Integration of mental health into primary care services can be a cost effective way of reducing the disability assoc... Read More about Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review.

Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan. (2023)
Journal Article
Valkovskaya, M., Hassan, A., Zartaloudi, E., Hussain, F., Umar, M., Khizar, B., …Kuchenbaecker, K. (2023). Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan. Psychiatric Genetics, 33(2), 69-78. https://doi.org/10.1097/ypg.0000000000000333

INTRODUCTION: Globally, 80% of the burdenof major depressive disorder (MDD) pertains to low- and middle-income countries. Research into genetic and environmental risk factors has the potential to uncover disease mechanisms that may contribute to bett... Read More about Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan..

Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study (2022)
Journal Article
Ishaq Khattak, M., Dikomitis, L., Firaz Khan, M., Ul Haq, M., Saeed, U., Riaz Awan, N., …Farooq, S. (2022). Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study. PloS one, https://doi.org/10.1371/journal.pone.0273286

OBJECTIVE: To explore the perceptions and experiences of schizophrenia from patients, their care givers, health care providers, spiritual and traditional healers to develop a community-based intervention for improving treatment adherence for people w... Read More about Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study.

Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia (2022)
Journal Article
Farooq, S., Hattle, M., Dazzan, P., Kingstone, T., Ajnakina, O., Shiers, D., …Van Der Windt, D. (in press). Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia. BMJ Open, 12(4), https://doi.org/10.1136/bmjopen-2021-056420

<jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Treatment Resistant Schizophrenia (TRS) is associated with significant impairment of functioning and high treatment costs. Identification of patients at high risk... Read More about Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia.

An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels (2021)
Journal Article
de Leon, J., Schoretsanitis, G., Smith, R. L., Molden, E., Solismaa, A., Seppälä, N., …Marder, S. R. (2021). An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels. Pharmacopsychiatry, 55(02), 73-86. https://doi.org/10.1055/a-1625-6388

This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug in the United States (US), and... Read More about An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels.

Suicide, self-harm and suicidal ideation during COVID-19: A systematic review (2021)
Journal Article
Farooq, S., Tunmore, J., Ali, W., & Ayub, M. (2021). Suicide, self-harm and suicidal ideation during COVID-19: A systematic review. Psychiatry Research, 306, Article ARTN 114228. https://doi.org/10.1016/j.psychres.2021.114228

We aimed to do a systematic review and meta-analysis of studies describing suicidal ideation, suicide attempts and suicide and associated risk factors during COVID-19 pandemic. We searched following electronic databases using relevant search terms: M... Read More about Suicide, self-harm and suicidal ideation during COVID-19: A systematic review.

The haematological side effects of clozapine: literature review and meta-analysis (2021)
Journal Article
Munshi, T., Naeem, F., Ayub, M., Farooq, S., Khachatryan, D., Asmer, S., …Fairbairn, J. (2021). The haematological side effects of clozapine: literature review and meta-analysis. BJPsych Open, 7(S1), https://doi.org/10.1192/bjo.2021.729

Aims
This review and meta-analysis aim to estimate the cumulative incidence of clozapine induced agranulocytosis and leukopenia the impact of the associated factors such as dose of clozapine, duration of follow-up, gender and race on the cumulative... Read More about The haematological side effects of clozapine: literature review and meta-analysis.

Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data (2021)
Journal Article
Farooq. (2021). Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data. BMJ Open, 1-9. https://doi.org/10.1136/bmjopen-2020-042331

Introduction Individuals with schizophrenia are at a high risk of physical health comorbidities and premature mortality. Cardiovascular and metabolic causes are an important contributor. There are gaps in monitoring, documenting and managing these ph... Read More about Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data.

Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives (2021)
Journal Article
Nash, A., Kingstone, T., Farooq, S., Tunmore, J., & Chew-Graham, C. A. (2021). Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives. BMJ Open, e042497 - ?. https://doi.org/10.1136/bmjopen-2020-042497

OBJECTIVES: The side effects of antipsychotic medications (APs) can increase the risk of developing physical health conditions. Some APs pose a higher risk than others. Evidence suggests switching to lower risk APs can support physical health outcome... Read More about Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives.