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Joint replacement surgery for elbow tumours: a systematic review of outcomes (2021)
Journal Article
Manoharan, G., Jordan, R. W., Orfanos, G., Cheruvu, M. S., Cool, P., & Hay, S. M. (2021). Joint replacement surgery for elbow tumours: a systematic review of outcomes. Shoulder and Elbow, 13(6), 656-670. https://doi.org/10.1177/17585732211014832

Background
Tumour resection followed by joint reconstruction is a surgical option in the appropriate patient. The evidence for such reconstructive surgery of the elbow joint is limited. The aim of this study is to review the literature to evaluate t... Read More about Joint replacement surgery for elbow tumours: a systematic review of outcomes.

How a Pandemic Changes Trauma: Epidemiology and Management of Trauma Admissions in the UK during COVID-19 Lockdown. (2021)
Journal Article
Dass, D., Ramhamadany, E., Govilkar, S., Rhind, J., Ford, D., Singh, R., …Cool, P. (2021). How a Pandemic Changes Trauma: Epidemiology and Management of Trauma Admissions in the UK during COVID-19 Lockdown. Journal of Emergencies, Trauma, and Shock, 14(2), 75 - 79. https://doi.org/10.4103/JETS.JETS_137_20

Introduction: On June 24 in the United Kingdom, there were 277,989 cases of COVID-19 and 39,369 deaths recorded. The government enforced a complete lockdown on March 23 that resulted in cessation of all elective admissions on 24th onward, with only a... Read More about How a Pandemic Changes Trauma: Epidemiology and Management of Trauma Admissions in the UK during COVID-19 Lockdown..

Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions (2021)
Journal Article
Western, L. F., Dhawan, R., Cribb, G., Shepherd, K., & Cool, P. (2021). Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions. Cureus, 13(2), Article e13565. https://doi.org/10.7759/cureus.13565

Background
Bone tumours of the talus are a rare cause of ankle pain. This study aims to provide additional clinical clarity regarding the presentation and management of a minimally researched topic.

Methods
Sixteen patients were diagnosed with b... Read More about Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions.

What Proportion of Patients with Bone and Soft Tissue Tumors Contracted Coronavirus-19 and Died From Surgical Procedures During the Initial Period of the COVID-19 Pandemic? Results From the Multicenter British Orthopaedic Oncology Society Observational Study (2020)
Journal Article
Rajasekaran, R. B., Ashford, R. U., Cosker, T. D. A., Stevenson, J. D., Jeys, L., Pollock, R., …Cool, W. (2021). What Proportion of Patients with Bone and Soft Tissue Tumors Contracted Coronavirus-19 and Died From Surgical Procedures During the Initial Period of the COVID-19 Pandemic? Results From the Multicenter British Orthopaedic Oncology Society Observational Study. Clinical Orthopaedics and Related Research, 479(5), 1158-1166. https://doi.org/10.1097/corr.0000000000001568

Delivering uninterrupted cancer treatment to patients with musculoskeletal tumors has been essential during the rapidly evolving coronavirus 2019 (COVID-19) pandemic, as delays in management can be detrimental. Currently, the risk of contracting COVI... Read More about What Proportion of Patients with Bone and Soft Tissue Tumors Contracted Coronavirus-19 and Died From Surgical Procedures During the Initial Period of the COVID-19 Pandemic? Results From the Multicenter British Orthopaedic Oncology Society Observational Study.

Bone biopsy results in patients with a history of malignancy: a case series of 378 patients (2020)
Journal Article
Morris, R., Shepherd, K., Cribb, G., Singh, J., Tyrrell, P., & Cool, P. (2021). Bone biopsy results in patients with a history of malignancy: a case series of 378 patients. Skeletal Radiology, 50(6), 1111-1116. https://doi.org/10.1007/s00256-020-03652-0

Objective
The value of a bone biopsy in patients who present with a bone lesion and past medical history of malignancy is uncertain. The objective of this study was to evaluate the outcome of bone biopsies in patients with a history of a malignancy... Read More about Bone biopsy results in patients with a history of malignancy: a case series of 378 patients.

Intraosseous lipomas originating from simple bone cysts (2020)
Journal Article
Tins, B. J., Berkowitz, Y. J., Konala, P., Davies, M., Cassar-Pullicino, V. N., Lalam, R., & Cool, P. (2021). Intraosseous lipomas originating from simple bone cysts. Skeletal Radiology, 50(4), 801-806. https://doi.org/10.1007/s00256-020-03628-0

Purpose
Fatty or part-fatty intraosseous lesions are occasionally encountered while imaging the skeletal system. A number of case reports have proposed involution of calcaneal bone cysts to intraosseous lipomas, but this has never been proven. This... Read More about Intraosseous lipomas originating from simple bone cysts.

Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury (2020)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Osman, A., Roy Chowdhury, J., Kumar, N., …Wright, K. (2020). Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury. Journal of Neurotrauma, 38(3), https://doi.org/10.1089/neu.2020.7144

Neurological outcomes following spinal cord injury (SCI) are currently difficult to predict. Whilst the initial American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade can give an estimate of outcome, the high remaining degree of uncer... Read More about Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury.

Effect of COVID-19 on a rural orthopaedic hip fracture service (2020)
Journal Article
Cool. (2020). Effect of COVID-19 on a rural orthopaedic hip fracture service. Bone & Joint Open, 1(8), 500 - 507. https://doi.org/10.1302/2633-1462.18.BJO-2020-0082.R1

Aims: Our rural orthopaedic service has undergone service restructure during the COVID-19 pandemic in order to sustain hip fracture care. All adult trauma care has been centralised to the Royal Shrewsbury Hospital for assessment and medical input, be... Read More about Effect of COVID-19 on a rural orthopaedic hip fracture service.

Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone (2020)
Journal Article
Howard, E. L., Gregory, J., Tsoi, K., Evans, S., Flanagan, A., & Cool, P. (2020). Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone. Cureus, 12(7), Article e9164. https://doi.org/10.7759/cureus.9164

This study evaluates the relationship between pregnancy, comorbid conditions and giant cell tumour of bone. Furthermore, it examines if pregnancy and comorbid conditions affect the outcome following treatment for this tumour. A multi-centre retrospec... Read More about Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone.

Radiological Features of Giant Cell Tumours of Bone (2020)
Journal Article
Howard, E. L., Gregory, J., Winn, N., Flanagan, A., & Cool, P. (2020). Radiological Features of Giant Cell Tumours of Bone. Cureus, 12(6), Article e8793. https://doi.org/10.7759/cureus.8793

Introduction The aim of this study was to evaluate radiological measurements to establish the origin of giant cell tumours of bone. Methods A multi-centre retrospective review was conducted of patients with histologically confirmed giant cell tumours... Read More about Radiological Features of Giant Cell Tumours of Bone.

From Elective Orthopaedic Centre to a COVID-19 Trauma Unit: Rapid transformation (2020)
Journal Article
Govilkar, S., Dover, C., Dass, D., Rhind, J., Ramhamadany, E., Ford, D., …Kelly, C. (2020). From Elective Orthopaedic Centre to a COVID-19 Trauma Unit: Rapid transformation. The Transient Journal of Trauma, Orthopaedics and the Coronavirus (TJTO&C),

The medical profession is facing one of its biggest challenges in modern history. Declared as the cause of a global pandemic by the World Health Organisation on 11th March 2020, COVID-19 has now been confirmed in over 3.5 million people worldwide. CO... Read More about From Elective Orthopaedic Centre to a COVID-19 Trauma Unit: Rapid transformation.

Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI (2020)
Journal Article
Cool. (2020). Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI. Skeletal Radiology, 49, 869–881. https://doi.org/10.1007/s00256-019-03363-1

OBJECTIVE: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possibl... Read More about Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI.

Excised Femoral Heads in Hip Fracture Patients: Is Osteoporosis Worse Than Cancer? (2019)
Journal Article
Salar, O., Crosswell, S., Ghani, R., Rao, P., Meyer, C., Hay, S., …Cool, P. (2019). Excised Femoral Heads in Hip Fracture Patients: Is Osteoporosis Worse Than Cancer?. Cureus, 11(12), Article e6455. https://doi.org/10.7759/cureus.6455

Introduction
Annually 80,000 hip fractures are treated at an estimated cost of two billion pounds. The 2011 guidance from the Royal College of Pathologists recommended all specimens where there is fracture through or below the articular surface shou... Read More about Excised Femoral Heads in Hip Fracture Patients: Is Osteoporosis Worse Than Cancer?.

Prediction of pathological fracture in patients with metastatic disease of the lower limb (2019)
Journal Article
Cool. (in press). Prediction of pathological fracture in patients with metastatic disease of the lower limb. Scientific reports, 9, Article 14133. https://doi.org/10.1038/s41598-019-50636-9

The aim of this study was to investigate if the risk of pathological fracture can be predicted with the proportion of body weight that can be put through the affected leg in patients with metastatic bone disease of the lower limb. A prospective obser... Read More about Prediction of pathological fracture in patients with metastatic disease of the lower limb.

Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement (2019)
Journal Article
Amary, F., Perez-Casanova, L., Ye, H., Cottone, L., Strobl, A., Cool, P., …Flanagan, A. M. (2019). Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement. Modern Pathology, 32(12), 1762-1771. https://doi.org/10.1038/s41379-019-0315-8

A fusion between fibronectin 1 (FN1) and activin receptor 2A (ACVR2A) has been reported previously in isolated cases of the synovial chondromatosis. To analyze further and validate the findings, we performed FISH and demonstrated recurrent FN1–ACVR2A... Read More about Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement.

Prognostic indicators of outcome for patients with skeletal metastases from carcinoma of the prostate (2018)
Journal Article
Shepherd, K. L., Cool, P., & Cribb, G. (2018). Prognostic indicators of outcome for patients with skeletal metastases from carcinoma of the prostate. The Bone & Joint Journal, 100B(12), 1647-1654. https://doi.org/10.1302/0301-620X.100B12.BJJ-2018-0697.R1

Aims
The purpose of this study was to identify prognostic indicators of outcome at presentation to the orthopaedic surgeon, in patients with metastatic prostate cancer. Our aim was to use this information in a pragmatic, clinic-based approach so tha... Read More about Prognostic indicators of outcome for patients with skeletal metastases from carcinoma of the prostate.