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Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care. (2022)
Journal Article
Payne, R. A., Blair, P. S., Caddick, B., Chew-Graham, C. A., Dreischulte, T., Duncan, L. J., …McCahon, D. (in press). Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care. NIHR Open Research, 2, 54. https://doi.org/10.3310/nihropenres.13285.1

IntroductionPolypharmacy is increasingly common, and associated with undesirable consequences. Polypharmacy management necessitates balancing therapeutic benefits and risks, and varying clinical and patient priorities. Current guidance for managing p... Read More about Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care..

Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study) (2022)
Journal Article
Mamas. (2022). Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study). American Journal of Cardiology, 186, 71 - 79. https://doi.org/10.1016/j.amjcard.2022.10.023

Female gender has been shown to be associated with worse clinical outcomes after percutaneous coronary intervention (PCI). However, the impact of gender on the clinical outcomes of complex PCI is still poorly understood. This study examined the diffe... Read More about Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study).

Cardiometabolic risk profiles in a Sri Lankan twin and singleton sample. (2022)
Journal Article
(2022). Cardiometabolic risk profiles in a Sri Lankan twin and singleton sample. PloS one, e0276647 - ?

INTRODUCTION: Prevention of cardiovascular disease and diabetes is a priority in low- and middle-income countries, especially in South Asia where these are leading causes of morbidity and mortality. The metabolic syndrome is a tool to identify cardio... Read More about Cardiometabolic risk profiles in a Sri Lankan twin and singleton sample..

The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies. (2022)
Journal Article
Mamas, M. (2022). The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies. Nutrition Reviews, 2275 - 2287. https://doi.org/10.1093/nutrit/nuac034

CONTEXT AND OBJECTIVE: The impact of existing malnutrition on stroke outcomes is poorly recognised and treated. Evidence was systematically reviewed and quantified by meta-analysis. METHODS: MEDLINE, EMBASE and Web of Science were searched from incep... Read More about The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies..

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice (2022)
Journal Article
Schreiber, K., Frishman, M., Russell, M. D., Dey, M., Flint, J., Allen, A., …Williams, E. (2023). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice. Rheumatology, 62(4), e89-e104. https://doi.org/10.1093/rheumatology/keac552

Executive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., …Williams, E. (2023). Executive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), 1370-1387. https://doi.org/10.1093/rheumatology/keac558

Executive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice (2022)
Journal Article
Schreiber, K., Frishman, M., Russell, M. D., Dey, M., Flint, J., Allen, A., …Williams, E. (2023). Executive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice. Rheumatology, 62(4), 1388-1397. https://doi.org/10.1093/rheumatology/keac559

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., …Williams, E. (2022). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), e48-e88. https://doi.org/10.1093/rheumatology/keac551

Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme (2022)
Journal Article
Philp, F., Faux-Nightingale, A., Bateman, J., Clark, H., Johnson, O., Klaire, V., …M Singh, B. (2022). Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme. BMJ Open, 12(11), Article e065709. https://doi.org/10.1136/bmjopen-2022-065709

OBJECTIVES: The association between impaired digital provision, access and health outcomes has not been systematically studied. The Wolverhampton Digital ENablement programme (WODEN) is a multiagency collaborative approach to determine and address di... Read More about Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme.

Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations (2022)
Journal Article
Campanholo, C. B., Maharaj, A. B., Corp, N., Bell, S., Costa, L., de Vlam, K., …Ogdie, A. (2022). Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations. The Journal of Rheumatology, 50(3), 426 - 432. https://doi.org/10.3899/jrheum.220310

Objective: The 2021 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations provide an evidence-based guide for selecting therapy based on the individual’s disease features. Beyond the disease feature... Read More about Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations.

Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry) (2022)
Journal Article
Mamas. (2022). Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry). American Journal of Cardiology, 1 - 7. https://doi.org/10.1016/j.amjcard.2022.07.039

QRS duration (QRSd) is ill-defined and under-researched as a prognosticator in patients with non–ST-segment myocardial infarction (NSTEMI). We analyzed 240,866 adult (=18 years) hospitalizations with non–ST-segment elevation myocardial infarction usi... Read More about Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry).

Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes (2022)
Journal Article
Mamas. (2022). Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes. Diabetes Care, 2737-2745. https://doi.org/10.2337/dc22-0894

OBJECTIVE Heart failure (HF) often develops in patients with diabetes and is recognized for its role in increased cardiovascular morbidity and mortality in this population. Most existing models predict risk in patients with prevalent rather than i... Read More about Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes.

Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. (2022)
Journal Article
Elbadawi, A., Sedhom, R., Gad, M., Hamed, M., Elwagdy, A., Barakat, A. F., …Jneid, H. (2022). Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. European Journal of Internal Medicine, 105, 38 - 45. https://doi.org/10.1016/j.ejim.2022.07.015

BACKGROUND: Randomized controlled trials (RCTs) investigating the optimal screening strategy for atrial fibrillation (AF) have yielded conflicting results. OBJECTIVE: To examine the comparative efficacy of different AF screening strategies in old... Read More about Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials..

Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. (2022)
Journal Article
Nolan. (2022). Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. Frontiers in Cardiovascular Medicine, 1022415 - ?. https://doi.org/10.3389/fcvm.2022.1022415

BACKGROUND: Old age and the presence of aortic stenosis are associated with the unfolding of the intrathoracic aorta. This may result in increased difficulties navigating catheters from the right compared to the left radial approach. OBJECTIVE: To in... Read More about Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis..

Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. (2022)
Journal Article
Mamas. (2022). Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. https://doi.org/10.1080/14779072.2022.2138858

BACKGROUND: A significant proportion of the world's population lives with physical disability (PD) requiring healthcare services. Risk factors for cardiovascular disease (CVD) such as hypertension and diabetes are more prevalent among patients with P... Read More about Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States..

Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group (2022)
Journal Article
Holden, M., Metcalf, B., Lawford, B., Hinman, R., Boyd, M., Button, K., …Bennell, K. (2023). Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group. Osteoarthritis and Cartilage, 31(3), 386-396. https://doi.org/10.1016/j.joca.2022.10.009

Objective To develop evidence-informed recommendations to support the delivery of best practice therapeutic exercise for people with knee and/or hip osteoarthritis (OA). Design A multi-stage, evidence-informed, international multi-disciplinary c... Read More about Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group.

Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions (2022)
Journal Article
Bullock-Palmer, R. P., Bravo-Jaimes, K., Mamas, M. A., & Grines, C. L. (2022). Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions. European Cardiology Review, 17, https://doi.org/10.15420/ecr.2022.23

In the past few decades, the accelerated improvement in technology has allowed the development of new and effective coronary and structural heart disease interventions. There has been inequitable patient access to these advanced therapies and signifi... Read More about Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions.

Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies. (2022)
Journal Article
Kwok, C., Muntean, E., Mallen, C., & Borovac, J. (2022). Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies. Clinics and Practice, 832 - 844. https://doi.org/10.3390/clinpract12060088

There is considerable interest in data analytics because of its value in informing decisions in healthcare. Data variables can be derived from routinely collected records or from primary studies. The level of detail for individual variables in quanti... Read More about Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies..

Is vaccination against COVID-19 associated with psoriasis or eczema flare? Self-controlled case series analysis using data from the Clinical Practice Research Datalink (Aurum) (2022)
Journal Article
Adams, L., Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Van-Tam, J. S. N., …Abhishek, A. (2023). Is vaccination against COVID-19 associated with psoriasis or eczema flare? Self-controlled case series analysis using data from the Clinical Practice Research Datalink (Aurum). British Journal of Dermatology, 188(2), 297-299. https://doi.org/10.1093/bjd/ljac061