All Outputs (17)

Duty, desire or indifference? A qualitative study of patient decisions about recruitment to an epilepsy treatment trial (2006)
Journal Article
Canvin. (2006). Duty, desire or indifference? A qualitative study of patient decisions about recruitment to an epilepsy treatment trial. Trials, https://doi.org/10.1186/1745-6215-7-32

Epilepsy is a common neurological condition, in which drugs are the mainstay of treatment and drugs trials are commonplace. Understanding why patients might or might not opt to participate in epilepsy drug trials is therefore of some importance, part... Read More about Duty, desire or indifference? A qualitative study of patient decisions about recruitment to an epilepsy treatment trial.

Disabling knee pain--another consequence of obesity: results from a prospective cohort study (2006)
Journal Article
Jinks, C., Jordan, K., & Croft, P. (2006). Disabling knee pain--another consequence of obesity: results from a prospective cohort study. BMC Public Health, 6, Article 258. https://doi.org/10.1186/1471-2458-6-258

Obesity is linked to knee osteoarthritis (OA) and knee pain. These are disabling problems that are more prevalent in older adults. No prospective study has estimated the impact of excess weight avoidance on the occurrence of knee pain in the general... Read More about Disabling knee pain--another consequence of obesity: results from a prospective cohort study.

The molecular epidemiology of Stenotrophomonas maltophilia bacteraemia in a tertiary referral hospital in the United Arab Emirates 2000-2004. (2006)
Journal Article
(2006). The molecular epidemiology of Stenotrophomonas maltophilia bacteraemia in a tertiary referral hospital in the United Arab Emirates 2000-2004. Annals of Clinical Microbiology and Antimicrobials, 32 - ?. https://doi.org/10.1186/1476-0711-5-32

BACKGROUND: Stenotrophomonas maltophilia is recognised as an important cause of nosocomial infection, especially in immunocompromised patients, resulting in significant morbidity and mortality. The treatment of S. maltophilia infection presents a the... Read More about The molecular epidemiology of Stenotrophomonas maltophilia bacteraemia in a tertiary referral hospital in the United Arab Emirates 2000-2004..

A prediction rule for shoulder pain related sick leave: a prospective cohort study. (2006)
Journal Article
Kuijpers, T., van der Windt, D., van der Heijden, G., Twisk, J., Vergouwe, Y., & Bouter, L. (2006). A prediction rule for shoulder pain related sick leave: a prospective cohort study. BMC Musculoskeletal Disorders, 97 - ?. https://doi.org/10.1186/1471-2474-7-97

Shoulder pain is common in primary care, and has an unfavourable outcome in many patients. Information about predictors of shoulder pain related sick leave in workers is scarce and inconsistent. The objective was to develop a clinical prediction rule... Read More about A prediction rule for shoulder pain related sick leave: a prospective cohort study..

Reproducibility and responsiveness of the Symptom Severity Scale and the hand and finger function subscale of the Dutch arthritis impact measurement scales (Dutch-AIMS2-HFF) in primary care patients with wrist or hand problems. (2006)
Journal Article
(2006). Reproducibility and responsiveness of the Symptom Severity Scale and the hand and finger function subscale of the Dutch arthritis impact measurement scales (Dutch-AIMS2-HFF) in primary care patients with wrist or hand problems. Health and Quality of Life Outcomes, 87 - ?. https://doi.org/10.1186/1477-7525-4-87

To determine the clinimetric properties of two questionnaires assessing symptoms (Symptom Severity Scale) and physical functioning (hand and finger function subscale of the AIMS2) in a Dutch primary care population.

The assessment of the prognosis of musculoskeletal conditions in older adults presenting to general practice: a research protocol (2006)
Journal Article
(2006). The assessment of the prognosis of musculoskeletal conditions in older adults presenting to general practice: a research protocol. BMC Musculoskeletal Disorders, 84 - ?. https://doi.org/10.1186/1471-2474-7-84

Musculoskeletal conditions represent a common reason for consulting general practice yet with the exception of low back pain, relatively little is known about the prognosis of these disorders. Recent evidence suggests that common 'generic' factors ma... Read More about The assessment of the prognosis of musculoskeletal conditions in older adults presenting to general practice: a research protocol.

Costs of shoulder pain in primary care consulters: a prospective cohort study in The Netherlands (2006)
Journal Article
(2006). Costs of shoulder pain in primary care consulters: a prospective cohort study in The Netherlands. BMC Musculoskeletal Disorders, 83 - ?. https://doi.org/10.1186/1471-2474-7-83

Shoulder pain is common in primary care, and has an unfavourable outcome in many patients. Information on the costs associated with health care use and loss of productivity in patients with shoulder pain is very scarce. The objective of this study wa... Read More about Costs of shoulder pain in primary care consulters: a prospective cohort study in The Netherlands.

The impact of workplace risk factors on the occurrence of neck and upper limb pain: a general population study (2006)
Journal Article
(2006). The impact of workplace risk factors on the occurrence of neck and upper limb pain: a general population study. BMC Public Health, 234 - ?. https://doi.org/10.1186/1471-2458-6-234

BACKGROUND: Work-related neck and upper limb pain has mainly been studied in specific occupational groups, and little is known about its impact in the general population. The objectives of this study were to estimate the prevalence and population imp... Read More about The impact of workplace risk factors on the occurrence of neck and upper limb pain: a general population study.

Studying Social Policy and Resilience to Adversity in Different Welfare States: Britain and Sweden (2006)
Journal Article
Jones, C., Burström, B., Marttila, A., Canvin, K., & Whitehead, M. (2006). Studying Social Policy and Resilience to Adversity in Different Welfare States: Britain and Sweden. International Journal of Health Services, 36(3), 425-442. https://doi.org/10.2190/E9H5-URYL-2W4U-QED6

Is poverty more damaging to health in Britain than in Sweden, and if so, why? Following previous research by the authors that suggested such an effect, a new comparative study is examining whether there are aspects of the social and policy context in... Read More about Studying Social Policy and Resilience to Adversity in Different Welfare States: Britain and Sweden.

IPSE/alpha-1: A major immunogenic component secreted from Schistosoma mansoni eggs (2006)
Journal Article
Schramm, G., Gronow, A., Knobloch, J., Wippersteg, V., Grevelding, C., Galle, J., …Doenhoff, M. (2006). IPSE/alpha-1: A major immunogenic component secreted from Schistosoma mansoni eggs. Molecular and Biochemical Parasitology, 147(1), 9-19. https://doi.org/10.1016/j.molbiopara.2006.01.003

During infection with Schistosoma mansoni the egg stage of this parasite modulates the initial T helper (Th1) response into a Th2 response. This suggests that schistosome eggs contain factors responsible for that effect. We have recently described a... Read More about IPSE/alpha-1: A major immunogenic component secreted from Schistosoma mansoni eggs.

Measuring troublesomeness of chronic pain by location (2006)
Journal Article
(2006). Measuring troublesomeness of chronic pain by location. BMC Musculoskeletal Disorders, 34 - ?. https://doi.org/10.1186/1471-2474-7-34

Current measures of pain assess the relative contribution of pain in different body regions to the overall impact of pain. We developed a series of questions to measure the relative 'troublesomeness' of pain in different body regions (the "troublesom... Read More about Measuring troublesomeness of chronic pain by location.

An enzyme-linked immunosorbent assay (ELISA) for the major crustacean allergen, tropomyosin, in food (2006)
Journal Article
Fuller, H. R., Goodwin, P. R., & Morris, G. E. (2006). An enzyme-linked immunosorbent assay (ELISA) for the major crustacean allergen, tropomyosin, in food. Food and Agricultural Immunology, 17(1), 43-52. https://doi.org/10.1080/09540100600572651

Shellfish are a common cause of food reactions in hypersensitive individuals and are among the eight foods that account for over 90% of food allergies. At present, the only way to prevent these serious consequences of food allergies is to avoid the f... Read More about An enzyme-linked immunosorbent assay (ELISA) for the major crustacean allergen, tropomyosin, in food.

Breast asymmetry and predisposition to breast cancer. (2006)
Journal Article
(2006). Breast asymmetry and predisposition to breast cancer. Breast Cancer Research, R14 - ?. https://doi.org/10.1186/bcr1388

INTRODUCTION: It has been shown in our previous work that breast asymmetry is related to several of the known risk factors for breast cancer, and that patients with diagnosed breast cancer have more breast volume asymmetry, as measured from mammogram... Read More about Breast asymmetry and predisposition to breast cancer..

The Knee Clinical Assessment Study-CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population: baseline recruitment and retention at 18 months (2006)
Journal Article
Dziedzic. (2006). The Knee Clinical Assessment Study-CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population: baseline recruitment and retention at 18 months. BMC Musculoskeletal Disorders, 30 - ?. https://doi.org/10.1186/1471-2474-7-30

Background Selective non-participation at baseline (due to non-response and non-consent) and loss to follow-up are important concerns for longitudinal observational research. We investigated these matters in the context of baseline recruitment and... Read More about The Knee Clinical Assessment Study-CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population: baseline recruitment and retention at 18 months.

Asthma severity and atopy: how clear is the relationship? (2006)
Journal Article
Carroll, W. D., Lenney, W., Child, F., Strange, R. C., Jones, P. W., Whyte, M. K., …Fryer, A. A. (2006). Asthma severity and atopy: how clear is the relationship?. Archives of Disease in Childhood, 91(5), 405 - 409. https://doi.org/10.1136/adc.2005.088278

BACKGROUND: The relationship between asthma severity and atopy is complex. Many studies have failed to show significant relationships between clinical severity or lung function and markers of atopic sensitisation. AIM: To determine whether increasing... Read More about Asthma severity and atopy: how clear is the relationship?.

Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system (2006)
Journal Article
Chari, D. M., Zhao, C., Kotter, M. R., Blakemore, W. F., & Franklin, R. J. (2006). Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. Journal of Neuroscience Research, 83(4), 594-605. https://doi.org/10.1002/jnr.20763

High dose corticosteroid (CS) administration is a common mode of therapy in treatment of acute relapses in multiple sclerosis (MS) but the effects of CS on remyelination and the cellular mechanisms mediating this repair process are controversial. We... Read More about Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system.

Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS (2006)
Journal Article
Chari, D. M., Gilson, J. M., Franklin, R. J., & Blakemore, W. F. (2006). Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS. Experimental Neurology, 198(1), 145-153. https://doi.org/10.1016/j.expneurol.2005.11.023

Oligodendrocyte lineage cells [oligodendrocytes and their parent cells, the oligodendrocyte progenitor cells (OPCs)] are depleted by X-irradiation and progenitor cell transplantation has been proposed as a therapeutic strategy to counteract radiation... Read More about Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS.