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Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management (2022)
Journal Article
Masiero, G., Paradies, V., Franzone, A., Bellini, B., De Biase, C., Karam, N., …Chieffo, A. (2022). Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management. Journal of the American Heart Association, 11(19), 1-15. https://doi.org/10.1161/jaha.121.025944

The impact of sex on pathophysiological processes, clinical presentation, treatment options, as well as outcomes of degenerative aortic stenosis remain poorly understood. Female patients are well represented in transfemoral aortic valve implantation... Read More about Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management.

'It's All Downhill from Here': A Scoping Review of Sports-Related Concussion (SRC) Protocols in Downhill Mountain Biking (DHI), with Recommendations for SRC Policy in Professional DMB. (2022)
Journal Article
Heron, N., McLarnon, M., Boyce, S., & Fisher, N. (2022). 'It's All Downhill from Here': A Scoping Review of Sports-Related Concussion (SRC) Protocols in Downhill Mountain Biking (DHI), with Recommendations for SRC Policy in Professional DMB. International Journal of Environmental Research and Public Health, 19(19), 12281. https://doi.org/10.3390/ijerph191912281

INTRODUCTION: Downhill mountain biking (DHI) is a form of cycling and does not currently have a specific sports-related concussion (SRC) assessment. OBJECTIVE: To review the extent, range and nature of research investigating SRC in DMB, provide a sum... Read More about 'It's All Downhill from Here': A Scoping Review of Sports-Related Concussion (SRC) Protocols in Downhill Mountain Biking (DHI), with Recommendations for SRC Policy in Professional DMB..

Cohort Profile: Institutional choice among medical applicants: a profile paper for The United Kingdom Medical Applicant Cohort Study (UKMACS) prospective longitudinal cohort study (2022)
Journal Article
Rees. (2022). Cohort Profile: Institutional choice among medical applicants: a profile paper for The United Kingdom Medical Applicant Cohort Study (UKMACS) prospective longitudinal cohort study. BMJ Open, https://doi.org/10.1136/bmjopen-2021-060135

Purpose:
To generate a large cohort of those in 2019 seriously considering applying to study Medicine, collecting data on a range of socio-economic and other demographic factors that influence choice of medical schools and to link to other datasets... Read More about Cohort Profile: Institutional choice among medical applicants: a profile paper for The United Kingdom Medical Applicant Cohort Study (UKMACS) prospective longitudinal cohort study.

Cluster A personality disorders and potential for early intervention in psychosis: Challenges and opportunities (2022)
Book Chapter
Farooq, S., & Ayub, M. (2022). Cluster A personality disorders and potential for early intervention in psychosis: Challenges and opportunities. In Psychosis and Personality Disorders (87-105). Springer. https://doi.org/10.1007/978-3-031-09058-5_5

The ‘Cluster A’ personality disorders consist of paranoid, schizoid and schizotypal personality disorders. The common features of personality disorders in this cluster are social awkwardness, social withdrawal, odd or eccentric behaviour and distorte... Read More about Cluster A personality disorders and potential for early intervention in psychosis: Challenges and opportunities.

Exploring the cultural effects of gender on perceptions of cutaneous leishmaniasis: a systematic literature review. (2022)
Journal Article
Wenning, B., Price, H., Nuwangi, H., Reda, K., Viana, G., Andras, A., …Ehsanullah, R. (2022). Exploring the cultural effects of gender on perceptions of cutaneous leishmaniasis: a systematic literature review. Global Health Research and Policy, 7, Article 34. https://doi.org/10.1186/s41256-022-00266-y

BACKGROUND: More than one million people each year become infected by parasites that cause the disease cutaneous leishmaniasis (CL). This disease manifests as one or more skin lesions or ulcers that are slow to heal with variable response rates to dr... Read More about Exploring the cultural effects of gender on perceptions of cutaneous leishmaniasis: a systematic literature review..

Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs. (2022)
Journal Article
Mamas. (2022). Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs. Journal of Cardiovascular Computed Tomography, https://doi.org/10.1016/j.jcct.2022.09.005

BACKGROUND: FFRCT assesses the functional significance of lesions seen on CTCA, and may be a more efficient approach to chest pain evaluation. The FORECAST randomized trial found no significant difference in costs within the UK National Health Servic... Read More about Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs..

The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism. (2022)
Journal Article
Mamas. (2022). The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism. International Journal of Cardiology, 354-362. https://doi.org/10.1016/j.ijcard.2022.09.049

OBJECTIVES: To evaluate the clinical care provided to cancer patients hospitalized for acute pulmonary embolism (PE), as well as the association between type of cancer, in-hospital care, and clinical outcomes.

METHODS: This study examined the in-... Read More about The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism..

Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling (2022)
Journal Article
Sumaya, W., Mamas, M. A., & Bagur, R. (2022). Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling. Journal of the American Heart Association, 11(19), https://doi.org/10.1161/JAHA.122.027165

Objectives
To evaluate the clinical care provided to cancer patients hospitalized for acute pulmonary embolism (PE), as well as the association between type of cancer, in-hospital care, and clinical outcomes.
Methods
This study examined the in-hos... Read More about Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling.

Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention. (2022)
Journal Article
Bashar, H., Matetić, A., Curzen, N., & Mamas, M. A. (2022). Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention. Catheterization and Cardiovascular Interventions, 100(5), 737-746. https://doi.org/10.1002/ccd.30404

OBJECTIVES: Extracardiac vascular disease (ECVD) is increasingly recognized as a cardiovascular risk factor, but its association with outcomes after percutaneous coronary intervention (PCI) has not been well characterized. METHODS: Using the National... Read More about Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention..

External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis (2022)
Journal Article
Hudda, M. T., Wells, J. C. K., Adair, L. S., Alvero-Cruz, J. R. A., Ashby-Thompson, M. N., Ballesteros-Vásquez, M. N., …Nightingale, C. M. (2022). External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis. BMJ, 378, e071185. https://doi.org/10.1136/bmj-2022-071185

Objective: To evaluate the performance of a UK based prediction model for estimating fat-free mass (and indirectly fat mass) in children and adolescents in non-UK settings. Design: Individual participant data meta-analysis. Setting: 19 countries. Par... Read More about External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis.

THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE (2022)
Presentation / Conference
Kesavan, S., Desai, R., Abbasi, A., & Muller, S. (2022, September). THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE. Poster presented at British Association for the Study of the Liver Annual Meeting

Background Upper gastrointestinal bleeding (UGIB) caused by gastro-oesophageal varices remains a common complication of cirrhosis with 10% mortality despite improvements in care. University Hospitals of North Midlands (UHNM) was identified by the pre... Read More about THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE.

TCT-146 Left Main Stem Percutaneous Coronary Intervention: Does Onsite Surgical Cover Make a Difference? (2022)
Journal Article
Mamas, & Rashid. (2022). TCT-146 Left Main Stem Percutaneous Coronary Intervention: Does Onsite Surgical Cover Make a Difference?. Journal of the American College of Cardiology, B59 - B59. https://doi.org/10.1016/j.jacc.2022.08.171

Background Nonsurgical centres (NSCs) contribute to the significant capacity of overall PCI in the UK. Whilst previous studies have demonstrated similar PCI outcomes in surgical centres (SCs) vs NSCs, it is unknown whether this applies to more comple... Read More about TCT-146 Left Main Stem Percutaneous Coronary Intervention: Does Onsite Surgical Cover Make a Difference?.

Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study (2022)
Presentation / Conference
Holland, D., Heald, A., Hanna, F., Wu, P., & Fry, A. (2022, September). Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study. Poster presented at 58 th EASD Annual Meeting of the European Association for the Study of Diabetes, Stockholm, Sweden

Background and aims: We have previously shown that, during the first 6 months of the UK COVID-19-associated lockdown, >6.6M HbA1c tests were missed/delayed, including 1.41M missed/delayed in people with diabetes (0.51M in those with suboptimal contro... Read More about Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study.

Management and outcomes of patients admitted with type 2 myocardial infarction with and without standard modifiable risk factors. (2022)
Journal Article
Rashid, M., Matetić, A., Lambrinou, E., Sokhal, B., Figtree, G., Moledina, S., …Velagapudi, P. (2022). Management and outcomes of patients admitted with type 2 myocardial infarction with and without standard modifiable risk factors. International Journal of Cardiology, 391-396. https://doi.org/10.1016/j.ijcard.2022.09.037

BACKGROUND: Whilst it is known patients without standard modifiable cardiovascular risk factors (SMuRF; hypertension, diabetes, hypercholesterolaemia, smoking) have worse outcomes in Type 1 acute myocardial infarction (AMI), the relationship between... Read More about Management and outcomes of patients admitted with type 2 myocardial infarction with and without standard modifiable risk factors..

Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study. (2022)
Journal Article
Mamas. (2022). Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study. Journal of Clinical Epidemiology, 176 - 184. https://doi.org/10.1016/j.jclinepi.2022.09.009

OBJECTIVES: In observational studies, researchers must select a method to control for confounding. Options include propensity score (PS) methods and regression. It remains unclear how dataset characteristics (size, overlap in PSs, and exposure preval... Read More about Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study..

Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS). (2022)
Journal Article
Mamas. (2022). Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS). Journal of Cardiovascular Computed Tomography, 17(1), 66 - 83. https://doi.org/10.1016/j.jcct.2022.09.002

Cardio-Oncology is a rapidly growing sub-specialty of medicine, however, there is very limited guidance on the use of cardiac CT (CCT) in the care of Cardio-Oncology patients. In order to fill in the existing gaps, this Expert Consensus statement com... Read More about Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS)..