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All Outputs (623)

Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques (2023)
Journal Article
Pate, A., Sperrin, M., Riley, R. D., Sergeant, J. C., Van Staa, T., Peek, N., …Martin, G. P. (2023). Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques. Statistics in Medicine, 42(18), 3184-3207. https://doi.org/10.1002/sim.9771

Introduction This study considers the prediction of the time until two survival outcomes have both occurred. We compared a variety of analytical methods motivated by a typical clinical problem of multimorbidity prognosis. Methods We considered f... Read More about Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques.

Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. (2023)
Journal Article
Welsh, V. K., Mason, K. J., Bailey, J., Bajpai, R., Jordan, K. P., Mallen, C. D., & Burton, C. (2023). Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. British Journal of General Practice (BJGP), 73(736), BJGP.2022.0648. https://doi.org/10.3399/bjgp.2022.0648

Background Rheumatic and musculoskeletal diseases (RMDs) are common and generally managed in primary care through supported self-care, physiotherapy, analgesia, and specialist referral where indicated. The COVID-19 pandemic led to abrupt changes in... Read More about Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study..

Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank (2023)
Journal Article
Remfry, E., Ardissino, M., McCracken, C., Szabo, L., Neubauer, S., Harvey, N. C., …Raisi-Estabragh, Z. (in press). Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcad029

Aim This study examined sex-based differences in associations of vascular risk factors with incident cardiovascular events in the UK Biobank. Methods Baseline participant demographic, clinical, laboratory, anthropometric, and imaging characteris... Read More about Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank.

Non-pharmacological interventions for the management of perinatal anxiety in primary care: A meta-review of systematic reviews (2023)
Journal Article
Silverwood, V., Bullock, L., Jordan, J., Turner, K., Chew-Graham, C. A., Kingstone, T., & Dawson, S. (in press). Non-pharmacological interventions for the management of perinatal anxiety in primary care: A meta-review of systematic reviews. British Journal of General Practice Open (BJGP Open), BJGPO.2023.0022. https://doi.org/10.3399/bjgpo.2023.0022

Perinatal anxiety (PNA), anxiety that occurs during pregnancy and/or up to 12 months post-partum, is estimated to affect up to 21% of women, and may impact negatively on mothers, children and their families. The National Institute for Health and Care... Read More about Non-pharmacological interventions for the management of perinatal anxiety in primary care: A meta-review of systematic reviews.

What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity (2023)
Journal Article
Rjoob, K., McGilligan, V., McAllister, R., Bond, R., Doolub, G., Leslie, S. J., …Peace, A. (2023). What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity. Catheterization and Cardiovascular Interventions, 102(1), 1-10. https://doi.org/10.1002/ccd.30684

Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review (2023)
Journal Article
Khan, M. F., Ul-Haq, Z., Ul Haq, M. M., Afridi, A., & Farooq, S. (2023). Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review. Pakistan Journal of Medical Sciences, 39(4), https://doi.org/10.12669/pjms.39.4.7286

Many people with Schizophrenia lack the resources and access to mental health services especially in low and middle income countries. Integration of mental health into primary care services can be a cost effective way of reducing the disability assoc... Read More about Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review.

The prevalence of children in the UK Cystic Fibrosis Registry on long term anti-Pseudomonas aeruginosa (PA) inhaled antibiotics who become culture negative for PA and a survey of practice for discontinuing treatment (2023)
Journal Article
Gilchrist, F., Davies, B., & Brodlie, M. (2023). The prevalence of children in the UK Cystic Fibrosis Registry on long term anti-Pseudomonas aeruginosa (PA) inhaled antibiotics who become culture negative for PA and a survey of practice for discontinuing treatment. Journal of Cystic Fibrosis, https://doi.org/10.1016/j.jcf.2023.05.007

An Evaluation of Different Strategies for Sampling Controls in an Online Case-Crossover Study of Acute Flares in Knee Osteoarthritis (2023)
Journal Article
Rathod-Mistry, T., Peat, G., Neogi, T., & Thomas, M. J. (2023). An Evaluation of Different Strategies for Sampling Controls in an Online Case-Crossover Study of Acute Flares in Knee Osteoarthritis. Clinical Epidemiology, Volume 15, 635-644. https://doi.org/10.2147/clep.s401488

Objective: To evaluate bias and precision of exposure-outcome effect estimates from three control sampling strategies in a case-crossover study. Methods: Online case-crossover study investigating eight physical activity-related triggers for acute fl... Read More about An Evaluation of Different Strategies for Sampling Controls in an Online Case-Crossover Study of Acute Flares in Knee Osteoarthritis.

Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis (2023)
Journal Article
Chong, B., Jayabaskaran, J., Ruban, J., Goh, R., Chin, Y. H., Kong, G., …Chew, N. W. (2023). Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Circulation: Cardiovascular Imaging, 16(5), https://doi.org/10.1161/circimaging.122.015159

Epicardial adipose tissue (EAT) has garnered attention as a prognostic and risk stratification factor for cardiovascular disease. This study, via meta-analyses, evaluates the associations between EAT and cardiovascular outcomes stratified across imag... Read More about Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis.

Suicide literacy mediates the path from religiosity to suicide stigma among Muslim community adults: Cross-sectional data from four Arab countries (2023)
Journal Article
Fekih-Romdhane, F., Daher-Nashif, S., Stambouli, M., Alhuwailah, A., Helmy, M., Shuwiekh, H. A. M., …Hallit, S. (in press). Suicide literacy mediates the path from religiosity to suicide stigma among Muslim community adults: Cross-sectional data from four Arab countries. International Journal of Social Psychiatry, 69(7), 1658-1669. https://doi.org/10.1177/00207640231174359

Background: The majority of research attention has been devoted to the link between religiosity and suicide risk, and a considerable amount of studies has been carried out on how stigma impacts individuals with mental health problems of different kin... Read More about Suicide literacy mediates the path from religiosity to suicide stigma among Muslim community adults: Cross-sectional data from four Arab countries.

Primary care-based models of care for osteoarthritis; a scoping review (2023)
Journal Article
Cunningham, J., Doyle, F., Ryan, J. M., Clyne, B., Cadogan, C., Cottrell, E., …French, H. P. (2023). Primary care-based models of care for osteoarthritis; a scoping review. Seminars in Arthritis and Rheumatism, 61, Article 152221. https://doi.org/10.1016/j.semarthrit.2023.152221

Objective To identify and describe the extent, nature, characteristics, and impact of primary care-based models of care (MoCs) for osteoarthritis (OA) that have been developed and/or evaluated. Design Six electronic databases were searched from... Read More about Primary care-based models of care for osteoarthritis; a scoping review.

Implementation of a primary care asthma management quality improvement programme across 68 general practice sites (2023)
Journal Article
Gilchrist, F. J., Carroll, W. D., Clayton, S., Price, D., Jarrold, I., Small, I., …Lenney, W. (in press). Implementation of a primary care asthma management quality improvement programme across 68 general practice sites. npj Primary Care Respiratory Medicine, 33(1), Article 21. https://doi.org/10.1038/s41533-023-00341-y

Despite national and international guidelines, asthma is frequently misdiagnosed, control is poor and unnecessary deaths are far too common. Large scale asthma management programme such as that undertaken in Finland, can improve asthma outcomes. A pr... Read More about Implementation of a primary care asthma management quality improvement programme across 68 general practice sites.

Moral judgement and decision-making: theoretical predictions and null results (2023)
Journal Article
Hertz, U., Jia, F., & Francis, K. B. (2023). Moral judgement and decision-making: theoretical predictions and null results. Scientific reports, 13(1), Article ARTN 7688. https://doi.org/10.1038/s41598-023-34899-x

The study of moral judgement and decision making examines the way predictions made by moral and ethical theories fare in real world settings. Such investigations are carried out using a variety of approaches and methods, such as experiments, modeling... Read More about Moral judgement and decision-making: theoretical predictions and null results.

Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis (2023)
Journal Article
Muhyieddeen, A., Cheng, S., Mamas, M. A., Beasley, D., Weins, G. C., & Gulati, M. (2023). Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis. Current Problems in Cardiology, 48(9), Article 101798. https://doi.org/10.1016/j.cpcardiol.2023.101798

This study assessed the COVID-19 pan-demic's impact on racial disparities in acute myocar-dial infarction (AMI) management and outcomes. We reviewed AMI patient management and outcomes in the pandemic's initial nine months, comparing COVID-19 and non... Read More about Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis.

The stigma associated with cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL): A protocol for a systematic review (2023)
Journal Article
Nuwangi, H., Agampodi, T. C., Price, H. P., Shepherd, T., Weerakoon, K. G., & Agampodi, S. B. (2023). The stigma associated with cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL): A protocol for a systematic review. PloS one, 18(5), Article ARTN e0285663. https://doi.org/10.1371/journal.pone.0285663

Leishmaniasis is a neglected tropical disease with three main clinical types; cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). CL and MCL are considered to be highly stigmatizing due to potentially dis... Read More about The stigma associated with cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL): A protocol for a systematic review.

Genomic Sequencing to Diagnose Prosthetic Joint Infection in the Knee: A Case Report (2023)
Journal Article
Wilkinson, H., McCarthy, H. S., Perry, J., Smith, T., Wright, K., & Cool, P. (2023). Genomic Sequencing to Diagnose Prosthetic Joint Infection in the Knee: A Case Report. Cureus, 15(5), https://doi.org/10.7759/cureus.38788

There is currently no "gold-standard" method to diagnose prosthetic joint infections (PJI), and the current practice of using microbiological cultures has many limitations. The identification of the bacterial species causing the infection is crucial... Read More about Genomic Sequencing to Diagnose Prosthetic Joint Infection in the Knee: A Case Report.

Living with persistent pain: A multi-method qualitative study to reducing opioids in the context of a pain review in primary care (2023)
Presentation / Conference
Woodcock, C., Cornwall, N., Harrisson, S., Knaggs, R., Pincus, T., Santar, M., …Jinks, C. (2023, May). Living with persistent pain: A multi-method qualitative study to reducing opioids in the context of a pain review in primary care. Paper presented at 56th Annual Scientific Meeting of the British Pain Society, Glasgow, Scotland, United Kingdom

Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis (2023)
Journal Article
Solis-Trapala, I., Campbell, P., Lacey, R., Rowlands, G., Dunn, K., & Protheroe, J. (2023). Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis. SSM - Population Health, 13, Article 101426. https://doi.org/10.1016/j.ssmph.2023.101426

Health literacy (HL), defined as the ability of an individual to understand and appraise health information to make informed decisions on their health, helps maintain and improve one's health and thus reduce the use of healthcare services. There is a... Read More about Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis.

The Utility of Salivary Cortisone in the Overnight Dexamethasone Suppression Test in Adrenal Incidentalomas (2023)
Journal Article
Issa, B. G., Hanna, F. W. F., Fryer, A. A., Ensah, G., Ebere, I., Marshall, D., & Keevil, B. (2023). The Utility of Salivary Cortisone in the Overnight Dexamethasone Suppression Test in Adrenal Incidentalomas. Journal of Clinical Endocrinology and Metabolism, 108(10), e937-e943. https://doi.org/10.1210/clinem/dgad242

BackgroundGuidelines recommend the assessment of cortisol secretion in patients with adrenal incidentalomas (AI) using the overnight dexamethasone suppression test (ONDST). This requires attendance to a health care facility and venepuncture. Alternat... Read More about The Utility of Salivary Cortisone in the Overnight Dexamethasone Suppression Test in Adrenal Incidentalomas.