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All Outputs (303)

An evaluation of a public partnership project between academic institutions and young people with Black African, Asian and Caribbean heritage (2024)
Journal Article
Moult, A., Knight, N., Medina, N., Babatunde, O., Kingstone, T., Duffy, H., …Dziedzic, K. (in press). An evaluation of a public partnership project between academic institutions and young people with Black African, Asian and Caribbean heritage. Research Involvement and Engagement, 10(1), Article 31. https://doi.org/10.1186/s40900-024-00564-4

Background: This project (named Reinvent) aimed to promote Public Involvement (PI) in health research. Academics worked with a community group, the Eloquent Praise & Empowerment Dance Company, to develop a community partnership with young people from... Read More about An evaluation of a public partnership project between academic institutions and young people with Black African, Asian and Caribbean heritage.

International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS (2024)
Journal Article
Nitta, K., Bieber, B., Karaboyas, A., Johnson, D. W., Kanjanabuch, T., Kim, Y., …Kawanishi, H. (2024). International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 14(3), https://doi.org/10.1177/08968608241235516

Background: Mineral bone disorder (MBD) in chronic kidney disease (CKD) is associated with high symptom burden, fractures, vascular calcification, cardiovascular disease and increased morbidity and mortality. CKD-MBD studies have been limited in per... Read More about International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS.

Collaboration across the primary/specialist interface in early intervention in psychosis services: a qualitative study (2024)
Journal Article
Rickett, M. C., Kingstone, T., Gupta, V., Shiers, D., French, P., Lennox, B., …Chew-Graham, C. A. (in press). Collaboration across the primary/specialist interface in early intervention in psychosis services: a qualitative study. British Journal of General Practice (BJGP), BJGP.2023.0558. https://doi.org/10.3399/bjgp.2023.0558

Background People with new psychotic symptoms may be managed within an Early Intervention in Psychosis service (EIP). They may be discharged back to primary care at the end of their time in an EIP service. Aim To explore the role of primary care in s... Read More about Collaboration across the primary/specialist interface in early intervention in psychosis services: a qualitative study.

Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ). (2024)
Journal Article
Geraghty, A. W. A., Holt, S., Chew-Graham, C. A., Santer, M., Moore, M., Kendrick, T., …van Marwijk, H. (in press). Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ). British Journal of General Practice (BJGP), 74(744), e434-e441. https://doi.org/10.3399/BJGP.2023.0574

Primary care clinicians see people experiencing the full range of mental health problems. Determining when symptoms reflect disorder is complex. The Four-Dimensional Symptom Questionnaire (4DSQ) uniquely distinguishes general distress from depressive... Read More about Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ)..

Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis (2024)
Journal Article
Walters, B., Midwinter, I., A. Chew-Graham, C., P. Jordan, K., Sharma, G., C. Chappell, L., …Wu, P. (2024). Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis. Mayo Clinic Proceedings, 8(2), 188-199. https://doi.org/10.1016/j.mayocpiqo.2024.02.002

This study aimed to systematically evaluate and quantify the risk of adverse maternal and neonatal outcomes in patients with pregnancy-associated cancer (PAC). This study was conducted from February 13, 2021, through July 24, 2023.... Read More about Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis.

Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis (2024)
Journal Article
Jeyaraman, D., Walters, B., Bramham, K., Fish, R., Lambie, M., & Wu, P. (2024). Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis. BJOG: An International Journal of Obstetrics and Gynaecology, https://doi.org/10.1111/1471-0528.17807

Background Chronic kidney disease (CKD) is associated with an increased risk of adverse pregnancy outcomes, but the risk at different stages of CKD (defined by estimated glomerular filtration rate, eGFR) compared with women without CKD has not been... Read More about Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis.

No-Reflow Prediction in Acute Coronary Syndrome During Percutaneous Coronary Intervention: The NORPACS Risk Score (2024)
Journal Article
Dawson, L. P., Rashid, M., Dinh, D. T., Brennan, A., Bloom, J. E., Biswas, S., …and BCIS Investigators, O. B. O. T. M. (2024). No-Reflow Prediction in Acute Coronary Syndrome During Percutaneous Coronary Intervention: The NORPACS Risk Score. Circulation: Cardiovascular Interventions, 17(4), https://doi.org/10.1161/circinterventions.123.013738

BACKGROUND: Suboptimal coronary reperfusion (no reflow) is common in acute coronary syndrome percutaneous coronary intervention (PCI) and is associated with poor outcomes. We aimed to develop and externally validate a clinical risk score for angiogr... Read More about No-Reflow Prediction in Acute Coronary Syndrome During Percutaneous Coronary Intervention: The NORPACS Risk Score.

Weight, weight gain and behavioural risk factors in women attending a breast cancer family history, risk and prevention clinic: an observational study (2024)
Journal Article
Pegington, M., Belcher, J., Barrett, E., Virpal, P., Howell, A., Evans, D. G., & Harvie, M. (in press). Weight, weight gain and behavioural risk factors in women attending a breast cancer family history, risk and prevention clinic: an observational study. BJC Reports, 2(1), Article 22. https://doi.org/10.1038/s44276-024-00039-9

Background: Weight and health behaviours impact on breast cancer risk. We describe trends in weight and health behaviours in women at entry to a specialist breast cancer family history clinic in Manchester, UK, and changes after clinic entry. Methods... Read More about Weight, weight gain and behavioural risk factors in women attending a breast cancer family history, risk and prevention clinic: an observational study.

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Steinmetz, J. D., Seeher, K. M., Schiess, N., Nichols, E., Cao, B., Servili, C., …Dua, T. (2024). Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Neurology, 23(4), 344-381. https://doi.org/10.1016/s1474-4422%2824%2900038-3

Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Globa... Read More about Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.

Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study (2024)
Journal Article
Turk, F., Sweetman, J., Chew‐Graham, C. A., Gabbay, M., Shepherd, J., & van der Feltz‐Cornelis, C. (2024). Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study. Health Expectations, 27(2), Article e14008. https://doi.org/10.1111/hex.14008

Background Long Covid is an emerging long-term condition, with those affected raising concerns about lack of healthcare support. Objective We conducted a qualitative study to identify facilitators and barriers to healthcare access for people wit... Read More about Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study.

Has the first year of the COVID pandemic impacted the trends in obesity-related CVD mortality between 1999 and 2019 in the United States? (2024)
Journal Article
Qamar, A., Abramov, D., Bang, V., Chew, N. W., Kobo, O., & Mamas, M. A. (2024). Has the first year of the COVID pandemic impacted the trends in obesity-related CVD mortality between 1999 and 2019 in the United States?. International Journal of Cardiology Cardiovascular Risk and Prevention, 21, 1-5. https://doi.org/10.1016/j.ijcrp.2024.200248

Background During the covid-19 pandemic there was a marked rise in the number of cardiovascular deaths. Obesity is a well-known modifiable risk factor for cardiovascular disease and has been identified as a factor... Read More about Has the first year of the COVID pandemic impacted the trends in obesity-related CVD mortality between 1999 and 2019 in the United States?.

Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases (2024)
Journal Article
Fuller, A., Hancox, J., Williams, H. C., Card, T., Taal, M. W., Aithal, G. P., …Abhishek, A. (2024). Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases. Rheumatology, Article keae175. https://doi.org/10.1093/rheumatology/keae175

To explore the acceptability of an individualised risk-stratified approach to monitoring for target-organ toxicity in adult patients with immune-mediated inflammatory diseases established on immune-suppressing treatment(s). Adults (≥18 years) taking... Read More about Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases.

Exploring the feasibility and acceptance of an optimised physiotherapy approach for lateral elbow tendinopathy: a qualitative investigation within the OPTimisE trial (2024)
Journal Article
Bateman, M., Saunders, B., Cooper, K., Littlewood, C., & Hill, J. C. (2024). Exploring the feasibility and acceptance of an optimised physiotherapy approach for lateral elbow tendinopathy: a qualitative investigation within the OPTimisE trial. BMJ Open, 14(3), Article e073816. https://doi.org/10.1136/bmjopen-2023-073816

Objectives: To explore the acceptability of an optimised physiotherapy (OPTimisE) intervention for people with lateral elbow tendinopathy (LET) and feasibility of comparing it to usual care in a randomised controlled trial. Design: Semistructured int... Read More about Exploring the feasibility and acceptance of an optimised physiotherapy approach for lateral elbow tendinopathy: a qualitative investigation within the OPTimisE trial.

Sex differences in trends and in-hospital outcomes of acute myocardial infarction in patients with familial hypercholesterolemia: insights from a large national database. (2024)
Journal Article
Rivera, F. B., Cha, S. W., Liston, M. B., Redula, S., Bantayan, N. R. B., Shah, N., …Mamas, M. A. (in press). Sex differences in trends and in-hospital outcomes of acute myocardial infarction in patients with familial hypercholesterolemia: insights from a large national database. Expert Review of Cardiovascular Therapy, 1-8. https://doi.org/10.1080/14779072.2024.2329720

Sex differences in clinical outcomes following acute myocardial infarction (AMI) are well known. However, data on sex differences among patients with familial hypercholesterolemia (FH) are limited. We aimed to explore sex differences in outcomes of A... Read More about Sex differences in trends and in-hospital outcomes of acute myocardial infarction in patients with familial hypercholesterolemia: insights from a large national database..

Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study (2024)
Journal Article
Hay, C. A., Packham, J., Prior, J. A., Mallen, C. D., & Ryan, S. (2024). Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study. Rheumatology International, 44, 863–884. https://doi.org/10.1007/s00296-024-05554-z

Diagnosis of axial spondyloarthritis (axSpA) is frequently delayed for years after symptom onset. However, little is known about patient and healthcare professional (HCP) perspectives on barriers and facilitators in axSpA diagnosis. This study explor... Read More about Barriers and facilitators in diagnosing axial spondyloarthritis: a qualitative study.

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Schumacher, A. E., Kyu, H. H., Aali, A., Abbafati, C., Abbas, J., Abbasgholizadeh, R., …Murray, C. J. L. (2024). Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. The Lancet, https://doi.org/10.1016/s0140-6736%2824%2900476-8

Background Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this... Read More about Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.

Performance Characteristics and Limitations of the Available Assays for the Detection and Quantitation of Monoclonal Free Light Chains and New Emerging Methodologies (2024)
Journal Article
Giles, H. V., & Karunanithi, K. (in press). Performance Characteristics and Limitations of the Available Assays for the Detection and Quantitation of Monoclonal Free Light Chains and New Emerging Methodologies. Antibodies, 13(1), Article 19. https://doi.org/10.3390/antib13010019

Light chain measurements form an essential component of the testing strategy for the detection and monitoring of patients with suspected and/or proven plasma cell disorders. Urine-based electrophoretic assays remain at the centre of the international... Read More about Performance Characteristics and Limitations of the Available Assays for the Detection and Quantitation of Monoclonal Free Light Chains and New Emerging Methodologies.

Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50 (2024)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., Kingston, A., & Wilkie, R. (2024). Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50. Scientific Reports, 14(1), Article 5936. https://doi.org/10.1038/s41598-024-53095-z

Although retirement ages are rising in the United Kingdom and other countries, the average number of years people in England can expect to spend both healthy and work from age 50 (Healthy Working Life Expectancy; HWLE) is less than the number of year... Read More about Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50.

Young people's priorities for the self‐management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique (2024)
Journal Article
Saunders, B., Polidano, K., Bray, L., Fisher, T., Corp, N., McDermott‐Hughes, M., …Chew‐Graham, C. A. (2024). Young people's priorities for the self‐management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique. Health Expectations, 27(2), Article e14009. https://doi.org/10.1111/hex.14009

Introduction The aim of this study was to gain consensus among young people with a stoma due to inflammatory bowel disease (IBD) on the priorities for the content of an intervention for the self-management of stoma-related distress. The current iden... Read More about Young people's priorities for the self‐management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique.