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All Outputs (303)

Greener Asthma Prescribing: A qualitative study exploring primary healthcare professional perspectives on reducing prescribing of metered dose inhalers for asthma (2024)
Thesis
Franklin, L. H. K. (2024). Greener Asthma Prescribing: A qualitative study exploring primary healthcare professional perspectives on reducing prescribing of metered dose inhalers for asthma. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/775420

Background: In 2020, the NHS developed its carbon net zero goals and highlighted metered dose inhalers (MDIs) as a focal point for change. MDIs are commonly prescribed for asthma in primary care and contain potent greenhouse gases, accounting for 3%... Read More about Greener Asthma Prescribing: A qualitative study exploring primary healthcare professional perspectives on reducing prescribing of metered dose inhalers for asthma.

Complex, high-risk but Indicated Percutaneous Coronary Interventions (CHiP) types, trends, and clinical outcomes (2024)
Thesis
Al-Shamkhani, W. S. J. (2024). Complex, high-risk but Indicated Percutaneous Coronary Interventions (CHiP) types, trends, and clinical outcomes. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/775413

Coronary artery disease ( CAD) remains the leading cause of death worldwide. Medical therapy and lifestyle modifications are the first line of therapy to minimise symptoms and retard disease progression. An Invasive therapy in the form of percutaneou... Read More about Complex, high-risk but Indicated Percutaneous Coronary Interventions (CHiP) types, trends, and clinical outcomes.

Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis (2024)
Thesis
Hay, C. A. (2024). Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/775300

Background: Axial spondyloarthritis (axSpA) causes inflammation of the pelvis and spine, resulting in chronic pain, impaired range of movement, fatigue and physical disability. Diagnosis remains challenging and is frequently delayed, resulting in poo... Read More about Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis.

Using Nanopore sequencing to identify bacterial infection in joint replacements: A Preliminary study (2024)
Journal Article
Wilkinson, H., McDonald, J., McCarthy, H., Perry, J., Wright, K., Hulme, C., & Cool, P. (in press). Using Nanopore sequencing to identify bacterial infection in joint replacements: A Preliminary study. Briefings in Functional Genomics, Article elae008. https://doi.org/10.1093/bfgp/elae008

This project investigates if third-generation genomic sequencing can be used to identify the species of bacteria causing prosthetic joint infections (PJIs) at the time of revision surgery. Samples of prosthetic fluid were taken during revision surger... Read More about Using Nanopore sequencing to identify bacterial infection in joint replacements: A Preliminary study.

Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Dawer, A., …Gairola, M. (in press). Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise. British Journal of Radiology, 97(1157), 913-919. https://doi.org/10.1093/bjr/tqae068

Oligometastatic Non-Small Cell Lung cancer (OMD NSCLC) has been proposed to bridge the spectrum between non-metastatic to widely metastatic states and is perceived as an opportunity for potential cure if removed. Twelve clinical trials on local treat... Read More about Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise.

Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh (2024)
Working Paper
Nayeem Hasan, M., Rahman, M., Fahim Uddin, M., Ali Akbar Ashrafi, S., Rahman, K. M., Kumar Paul, K., …Haider, N. Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh

In 2023, Bangladesh experienced its largest and deadliest outbreak of Dengue virus (DENV), reporting the highest-ever recorded annual cases and deaths. We aimed to characterize the geographical transmission of the DENV in Bangladesh. From 1 Jan – 31... Read More about Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh.

Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome (2024)
Journal Article
Mohamed, M., Ghosh, A. K., Banerjee, A., & Mamas, M. (in press). Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome. Canadian Journal of Cardiology, 40(6), 1146-1153. https://doi.org/10.1016/j.cjca.2024.03.012

Cancer and acute coronary syndrome (ACS) are the leading causes of morbidity and mortality globally, with many shared risk factors between both conditions. There are several challenges to the management of patients with cancer prese... Read More about Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome.

Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review (2024)
Journal Article
Farooq, S., Fonseka, N., Wajid Ali, M., Milner, A., Hamid, S., Sheikh, S., …Ayub, M. (2024). Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review. Schizophrenia Bulletin, Article sbae025. https://doi.org/10.1093/schbul/sbae025

Background and Hypothesis People with first-episode psychosis (FEP) in low- and lower-middle-income countries (LMIC) experience delays in receiving treatment, resulting in poorer outcomes and higher mortality. There is robust evidence for effective a... Read More about Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review.

The Evolving Field of Acute Coronary Syndrome Management: A Critical Appraisal of the 2023 European Society of Cardiology Guidelines for the Management of Acute Coronary Syndrome (2024)
Journal Article
Licordari, R., Costa, F., Garcia-Ruiz, V., Mamas, M. A., Marquis-Gravel, G., de la Torre Hernandez, J. M., …Micari, A. (in press). The Evolving Field of Acute Coronary Syndrome Management: A Critical Appraisal of the 2023 European Society of Cardiology Guidelines for the Management of Acute Coronary Syndrome. Journal of Clinical Medicine, 13(7), Article 1885. https://doi.org/10.3390/jcm13071885

Acute coronary syndromes (ACS), encompassing conditions like ST-elevation myocardial infarction (STEMI) and non-ST-elevation acute coronary syndromes (NSTE-ACS), represent a significant challenge in cardiovascular care due to their complex pathophysi... Read More about The Evolving Field of Acute Coronary Syndrome Management: A Critical Appraisal of the 2023 European Society of Cardiology Guidelines for the Management of Acute Coronary Syndrome.

Daily Pain Severity but Not Vertebral Fractures Is Associated With Lower Physical Activity in Postmenopausal Women With Back Pain (2024)
Journal Article
Montgomery, G., Tobias, J. H., Paskins, Z., Khera, T. K., Huggins, C. J., Allison, S. J., …Ireland, A. (2024). Daily Pain Severity but Not Vertebral Fractures Is Associated With Lower Physical Activity in Postmenopausal Women With Back Pain. Journal of Aging and Physical Activity, 1-10. https://doi.org/10.1123/japa.2023-0035

Back pain lifetime incidence is 60-70%, whilst 12-20% of older women have vertebral fractures (VFs), often with back pain. We aimed to provide objective evidence, currently lacking, regarding whether back pain and VFs affect physical activity (PA).... Read More about Daily Pain Severity but Not Vertebral Fractures Is Associated With Lower Physical Activity in Postmenopausal Women With Back Pain.

Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. (2024)
Journal Article
Archer, L., Relton, S. D., Akbari, A., Best, K., Bucknall, M., Conroy, S., …investigators, T. E. (2024). Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. Age and ageing, 53(3), Article afae057. https://doi.org/10.1093/ageing/afae057

Falls are common in older adults and can devastate personal independence through injury such as fracture and fear of future falls. Methods to identify people for falls prevention interventions are currently limited, with high risks of bias in publish... Read More about Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults..

Supporting people in Early Intervention in Psychosis services: the role of primary care. (2024)
Presentation / Conference
Chew-Graham, C., Rickett, M., Kingstone, T., Gupta, V., Shiers, D., French, P., …Ward, J. (2024, March). Supporting people in Early Intervention in Psychosis services: the role of primary care. Presented at BJGP Research and Publishing Conference, RCGP Headquarters, London

Early Intervention in Psychosis (EIP) services offer treatment to people experiencing a first episode of psychosis. Service users may be referred from primary care and discharged directly back at the end of their time in an EIP service. To explore th... Read More about Supporting people in Early Intervention in Psychosis services: the role of primary care..

How can we improve support for women with perinatal anxiety in primary care? A qualitative study. (2024)
Presentation / Conference
Silverwood, V., Fisher, T., Proctor, J., Kingstone, T., Turner, K., Shivji, N., & Chew-Graham, C. (2024, March). How can we improve support for women with perinatal anxiety in primary care? A qualitative study. Presented at BJGP Research and Publishing Conference, RCGP Headquarters, London

Perinatal anxiety (PNA) occurs during pregnancy and up to 12 months post-partum. PNA affects more than 21% of women and can impact adversely on mothers, children and their families. National Institute for Health and Care Excellence (NICE) guidance id... Read More about How can we improve support for women with perinatal anxiety in primary care? A qualitative study..

Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. (2024)
Presentation / Conference
Fisher, T., Archer, C., Bailey, J., Evans, J., Kessler, D. S., Kingstone, T., …Chew-Graham, C. (2024, March). Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. Presented at BJGP Research & Publishing Conference, RCGP Headquarters in London, England, UK

Perinatal anxiety (PNA) occurs throughout the antenatal period or up to 1 year after childbirth, with a prevalence of 21%. To investigate if primary care records could be used to identify women at 'higher risk' of PNA. Mixed-methods approach using qu... Read More about Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study..

Association of myocardial injury with adverse long-term survival among cancer patients. (2024)
Journal Article
Bashar, H., Kobo, O., Curzen, N., & Mamas, M. A. (in press). Association of myocardial injury with adverse long-term survival among cancer patients. European Journal of Preventive Cardiology, Article zwae116. https://doi.org/10.1093/eurjpc/zwae116

Over time, cardiovascular disease (CVD) deaths increasingly exceed those from malignancy among cancer survivors. However, the association of myocardial injury with long-term survival (beyond three years) in cancer patients has not been previously des... Read More about Association of myocardial injury with adverse long-term survival among cancer patients..

Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Ensor, J., Lam, N., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis. BMJ, 384, Article e077764. https://doi.org/10.1136/bmj-2023-077764

To synthesise evidence of the effectiveness of community based complex interventions, grouped according to their intervention components, to sustain independence for older people. Systematic review and network meta-analysis. Medline, Embase, CINAHL,... Read More about Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.

The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation (2024)
Journal Article
Stevenson, K., Hadley‐Barrows, T., Evans, N., Campbell, L., Southam, J., Chudyk, A., …Hill, J. C. (2024). The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation. Musculoskeletal Care, 22(1), Article e1876. https://doi.org/10.1002/msc.1876

Introduction Globally, back pain is the leading cause of years of disability. In the United Kingdom, over 20 million people live with musculoskeletal (MSK) pain, with low back pain being one of the most common causes. National strategies promote sel... Read More about The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation.

Individual Patient Data Meta-Analysis of Dynamic Cerebral Autoregulation and Functional Outcome After Ischemic Stroke. (2024)
Journal Article
Beishon, L., Vasilopoulos, T., Salinet, A. S. M., Levis, B., Barnes, S., Hills, E., …Nogueira, R. C. (in press). Individual Patient Data Meta-Analysis of Dynamic Cerebral Autoregulation and Functional Outcome After Ischemic Stroke. Stroke, 55(5), 1235-1244. https://doi.org/10.1161/STROKEAHA.123.045700

The relationship between dynamic cerebral autoregulation (dCA) and functional outcome after acute ischemic stroke (AIS) is unclear. Previous studies are limited by small sample sizes and heterogeneity. We performed a 1-stage individual patient data m... Read More about Individual Patient Data Meta-Analysis of Dynamic Cerebral Autoregulation and Functional Outcome After Ischemic Stroke..