All Outputs (1775)

Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis (2023)
Journal Article
Merfort, R., Maffulli, N., Hofmann, U. K., Hildebrand, F., Simeone, F., Eschweiler, J., & Migliorini, F. (in press). Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis. Scientific Reports, 13(1), Article 20327. https://doi.org/10.1038/s41598-023-47670-z

Total hip arthroplasty (THA) is a common procedure for patients suffering from hip pain e.g. from osteoarthritis, osteonecrosis, or hip fractures. The satisfaction of patients undergoing THA is influenced by the choice of implant type and material, w... Read More about Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis.

Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study (2023)
Journal Article
Schneider, J., Maffulli, N., Eschweiler, J., Bell, A., Hildebrand, F., & Migliorini, F. (in press). Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study. Scientific Reports, 13(1), Article 20210. https://doi.org/10.1038/s41598-023-47508-8

The prophylactic action of non-steroidal anti-inflammatory drugs (NSAIDs) in heterotopic ossification (HO) was first described following analgesic therapy with indomethacin. Following that evidence, several compounds have been successfully used for p... Read More about Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study.

Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction (2023)
Journal Article
Dimmock, R. L., Rotherham, M., El Haj, A. J., & Yang, Y. (in press). Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction. Gels, 9(11), Article 915. https://doi.org/10.3390/gels9110915

In the biomedical field, there is a demand for the development of novel approaches for the investigation of optical epithelial anatomical features with biomimetic materials. These materials are not only required to replicate structures but also enabl... Read More about Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction.

CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS (2023)
Journal Article
Lan, T., Wright, K., Makwana, N., Bing, A., McCarthy, H., & Hulme, C. (2023). CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS. Orthopaedic Proceedings, 105-B(SUPP_16), 62-62. https://doi.org/10.1302/1358-992x.2023.16.062

AbstractObjectivesBone marrow aspirate concentrate (BMAC), together with fibrin glue (Tisseel, Baxter, UK) and Hyaluronic acid (HA) were used as a one-step cell therapy treating patients with ankle cartilage defects in our hospital. This therapy was... Read More about CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS.

Artificial Intelligence and Machine Learning in Rotator Cuff Tears. (2023)
Journal Article
Rodriguez, H. C., Rust, B., Hansen, P. Y., Maffulli, N., Gupta, M., Potty, A. G., & Gupta, A. (in press). Artificial Intelligence and Machine Learning in Rotator Cuff Tears. Sports Medicine and Arthroscopy Review, 31(3), 67-72. https://doi.org/10.1097/JSA.0000000000000371

Rotator cuff tears (RCTs) negatively impacts patient well-being. Artificial intelligence (AI) is emerging as a promising tool in medical decision-making. Within AI, deep learning allows to autonomously solve complex tasks. This review assesses the cu... Read More about Artificial Intelligence and Machine Learning in Rotator Cuff Tears..

Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries. (2023)
Journal Article
Aratikatla, A., Sidhu, J., Maffulli, N., Gupta, M., Potty, A. G., & Gupta, A. (in press). Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries. Sports Medicine and Arthroscopy Review, 31(3), 73-79. https://doi.org/10.1097/JSA.0000000000000369

Highly prone to injury, the rotator cuff greatly contributes to the stability and mobility of the shoulder. Clinicians prioritize conservative treatment, resorting to surgery only when necessary, although they are hindered by inherent limitations. Bi... Read More about Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries..

EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW (2023)
Journal Article
Rix, L., Tushingham, S., Wright, K., & Snow, M. (2023). EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW. Orthopaedic Proceedings, 105-B(SUPP_16), 45-45. https://doi.org/10.1302/1358-992x.2023.16.045

AbstractObjectiveA common orthopaedic pain found in a wide spectrum of individuals, from young and active to the elderly is anterior knee pain (AKP). It is a multifactorial disorder which is thought to occur through muscular imbalance, overuse, traum... Read More about EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW.

SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS (2023)
Journal Article
Wright, K., McDonald, J., Mennan, C., Perry, J., Peffers, M., & Hulme, C. (2023). SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS. Orthopaedic Proceedings, 105-B(SUPP_16), 53-53. https://doi.org/10.1302/1358-992x.2023.16.053

AbstractObjectivesA promising therapy for early osteoarthritis (OA) is the transplantation of human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs). The synovial fluid (SF) from a pre-clinical ovine model treated with hUC-MSCs has been pr... Read More about SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS.

Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid (2023)
Journal Article
Lundeen, M., Hurd, J. L., Hayes, M., Hayes, M., Facile, T. R., Furia, J. P., …Pearce, D. A. (in press). Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid. Scientific Reports, 13(1), 19348. https://doi.org/10.1038/s41598-023-46653-4

Symptomatic, partial-thickness rotator cuff tears (sPTRCT) are problematic. This study tested the hypothesis that management of sPTRCT with injection of fresh, uncultured, unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) is safe... Read More about Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid.

Role of pan-national associations such as the European College of Sports and Exercise Physicians (ECOSEP) in advancing the specialty of sports and exercise medicine in the 21st century. (2023)
Journal Article
Scheer, V., Lohrer, H., Pakravan, A., Tsapralis, K., Valle, X., Ghrairi, M., …Bueno Padilla, J. M. (in press). Role of pan-national associations such as the European College of Sports and Exercise Physicians (ECOSEP) in advancing the specialty of sports and exercise medicine in the 21st century. BMJ Open Sport & Exercise Medicine, 9(4), Article e001703. https://doi.org/10.1136/bmjsem-2023-001703

Allogenic umbilical cord tissue for temporomandibular joint injuries (2023)
Journal Article
Aratikatla, A., Ghandour, S., Maffulli, N., Gupta, M., & Gupta, A. (in press). Allogenic umbilical cord tissue for temporomandibular joint injuries. Frontiers in Pain Research, 4, 1281277. https://doi.org/10.3389/fpain.2023.1281277

The temporomandibular joint (TMJ) is crucial for functions of daily living such as mastication and articulation. Common TMJ issues include osteoarthritis, internal derangement, and myofascial pain dysfunction. Conservative methods such as physical th... Read More about Allogenic umbilical cord tissue for temporomandibular joint injuries.

Circumferential Periosteal Release to Treat Paediatric Leg Length Discrepancy: Medium Term Outcomes. (2023)
Journal Article
Chatterton, B. D., Kuiper, J. H., & Williams, D. P. (2023). Circumferential Periosteal Release to Treat Paediatric Leg Length Discrepancy: Medium Term Outcomes. Strategies in Trauma and Limb Reconstruction, 18(2), 67-72. https://doi.org/10.5005/jp-journals-10080-1591

This study aims to report the medium term outcomes of circumferential periosteal release of the distal femur and distal tibia in treating paediatric leg length discrepancy (LLD). A retrospective case series was performed on all patients undergoing ci... Read More about Circumferential Periosteal Release to Treat Paediatric Leg Length Discrepancy: Medium Term Outcomes..

Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. (2023)
Journal Article
Atwal, A., Dale, T. P., Snow, M., Forsyth, N. R., & Davoodi, P. (2023). Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. Advances in colloid and interface science, 321, Article 103030. https://doi.org/10.1016/j.cis.2023.103030

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed significant challenges for healthcare practitioners, researchers, and individuals suffering from these conditions. Due to the absence of an approved treatmen... Read More about Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration..

Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study (2023)
Journal Article
Png, M. E., Mason, K. J., Marshall, M., Jordan, K. P., Bailey, J., Frisher, M., …Achana, F. (2023). Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study. Current Medical Research and Opinion, 1-8. https://doi.org/10.1080/03007995.2023.2271862

Objective To investigate the impact of pre-existing painful musculoskeletal conditions on healthcare utilization and costs among patients with five common conditions: acute coronary syndrome (ACS), stroke, cancer, dementia and pneumonia. Methods... Read More about Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study.

CT-based navigation for total hip arthroplasty: a meta-analysis (2023)
Journal Article
Migliorini, F., Cuozzo, F., Oliva, F., Eschweiler, J., Hildebrand, F., & Maffulli, N. (in press). CT-based navigation for total hip arthroplasty: a meta-analysis. European Journal of Medical Research, 28(1), Article 443. https://doi.org/10.1186/s40001-023-01437-4

Introduction: Computer tomography (CT) based navigation is considered by some authors as an advance in total hip arthroplasty (THA). A meta-analysis was conducted to compare CT based versus conventional THA in terms of surgical duration of the proced... Read More about CT-based navigation for total hip arthroplasty: a meta-analysis.

Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation (2023)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Z., Yang, Y., & Yuan, C. (2023). Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation. Journal of Materials Science, 58, Article 15499–15512

Marine biofouling presents a significant challenge to the sustainable development of the maritime industry. Antimicrobial peptide (AMP) offers a promising strategy to combat biofouling. However, the inherent susceptibility of natural AMPs composed of... Read More about Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation.

Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential (2023)
Journal Article
Clerici, M., Citro, V., Byrne, A. L., P. Dale, T., Boccaccini, A. R., Della Porta, G., …Forsyth, N. R. (2023). Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential. International Journal of Molecular Sciences, 24(20), Article 15107. https://doi.org/10.3390/ijms242015107

Tendon injuries caused by overuse or age-related deterioration are frequent. Incomplete knowledge of somatic tendon cell biology and their progenitors has hindered interventions for the effective repair of injured tendons. Here, we sought to compare... Read More about Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential.

Clinical gait analysis 1973-2023: Evaluating progress to guide the future. (2023)
Journal Article
Stebbins, J., Harrington, M., & Stewart, C. (2023). Clinical gait analysis 1973-2023: Evaluating progress to guide the future. Journal of Biomechanics, 160, Article 111827. https://doi.org/10.1016/j.jbiomech.2023.111827

Clinical gait analysis has been used to inform treatment for over 50 years. Over that period there have been significant advances in motion capture technology and software development, driven in part by innovations in biomechanics. The aim of this pa... Read More about Clinical gait analysis 1973-2023: Evaluating progress to guide the future..

Meniscectomy is associated with a higher rate of osteoarthritis compared to meniscal repair following acute tears: a meta-analysis. (2023)
Journal Article
Migliorini, F., Schäfer, L., Bell, A., Weber, C. D., Vecchio, G., & Maffulli, N. (in press). Meniscectomy is associated with a higher rate of osteoarthritis compared to meniscal repair following acute tears: a meta-analysis. Knee Surgery, Sports Traumatology, Arthroscopy, 31, 5485–5495. https://doi.org/10.1007/s00167-023-07600-y

Meniscal tears are common and may impair knee function and biomechanics. This meta-analysis compared meniscal repair versus resection in patients with symptomatic meniscal tears in terms of patient-reported outcomes measures (PROMs), joint width, sur... Read More about Meniscectomy is associated with a higher rate of osteoarthritis compared to meniscal repair following acute tears: a meta-analysis..

Relationship between deprivation, and the uptake and use of the common ailments service in community pharmacies in Wales (2023)
Journal Article
Thayer, N., Mackridge, A. J., & White, S. (2023). Relationship between deprivation, and the uptake and use of the common ailments service in community pharmacies in Wales. International Journal of Pharmacy Practice, https://doi.org/10.1093/ijpp/riad067

Since 2013 community pharmacies in Wales have been commissioned to provide a common ailments service (CAS), providing pharmacy medicine without charge to patients. In the first review of national pharmacy data, this study aimed to describe the relati... Read More about Relationship between deprivation, and the uptake and use of the common ailments service in community pharmacies in Wales.