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Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man (1991)
Journal Article
(1991). Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man. Journal of Experimental Medicine, 147 - 158. https://doi.org/10.1084/jem.173.1.147+%7C

When human peripheral blood lymphocytes (PBLs) from Epstein-Barr virus (EBV)-seropositive donors are injected intraperitoneally into SCID mice, EBV+ B cell tumors develop within weeks. A preliminary report (Mosier, D. E., R. J. Gulizia, S. M. Baird,... Read More about Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man.

Lipid peroxidation and expression of copper-zinc and manganese superoxide dismutase in lungs of premature infants with hyaline membrane disease and bronchopulmonary dysplasia. (1990)
Journal Article
Strange, R. C., Cotton, W., Fryer, A. A., Jones, P., Bell, J., & Hume, R. (1990). Lipid peroxidation and expression of copper-zinc and manganese superoxide dismutase in lungs of premature infants with hyaline membrane disease and bronchopulmonary dysplasia. Journal of Laboratory and Clinical Medicine, 116(5), 666-673

The putative involvement of reactive oxygen species in the etiology of lung damage in infants receiving mechanical ventilation has been examined by comparing the levels of peroxidation and expression of the antioxidant enzymes, CuZn and Mn superoxide... Read More about Lipid peroxidation and expression of copper-zinc and manganese superoxide dismutase in lungs of premature infants with hyaline membrane disease and bronchopulmonary dysplasia..

The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver. (1988)
Journal Article
Hiley, C., Fryer, A., Bell, J., Hume, R., & Strange, R. C. (1988). The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver. Biochemical Journal, 254(1), 255–259. https://doi.org/10.1042/bj2540255

Immunohistochemical studies of the developmental expression of the Alpha- and Pi-class glutathione S-transferases in human liver have shown that the Pi enzyme is expressed in bile-duct epithelium and some hepatocytes but not in haematopoietic cells.... Read More about The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver..

Studies on the expression of Cu,Zn superoxide dismutase in human tissues during development. (1988)
Journal Article
Strange, R. C., Cotton, W., Fryer, A. A., Drew, R., Bradwell, A. R., Marshall, T., …Hume, R. (1988). Studies on the expression of Cu,Zn superoxide dismutase in human tissues during development. BBA - Biochimica et Biophysica Acta, https://doi.org/10.1016/0304-4165%2888%2990174-2

The developmental expression of Cu,Zn superoxide dismutase in human lung and erythrocytes has been studied using activity measurements, immunoblotting and immunohistochemistry. Enzyme activity in erythrocytes increased significantly during gestation... Read More about Studies on the expression of Cu,Zn superoxide dismutase in human tissues during development..

Specific inhibition of the differentiation of Trypanosoma cruzi (1984)
Journal Article
(1984). Specific inhibition of the differentiation of Trypanosoma cruzi. Journal of Cell Biology, 79 -82. https://doi.org/10.1083/jcb.99.1.79

The morphological transformation of Trypanosoma cruzi amastigotes was studied in both mammalian cells and an extracellular differentiation system. Inhibitors of ADP-ribosyl transferase were found to block differentiation in both cases, without affect... Read More about Specific inhibition of the differentiation of Trypanosoma cruzi.

Mechanical loading of murine bioengineered skeletal muscle mimics the transcriptional & epigenetic response of human skeletal muscle after exercise
Journal Article
Mechanical loading of murine bioengineered skeletal muscle mimics the transcriptional & epigenetic response of human skeletal muscle after exercise. European cells & materials, 31 - 31

Recent investigations from our lab have characterised the genome-wide epigenetic (DNA methylation) and gene expression changes in skeletal muscle (SkM) following anabolic (resistance) exercise (RE) in humans [1]. We aimed to create 3D bioengineered S... Read More about Mechanical loading of murine bioengineered skeletal muscle mimics the transcriptional & epigenetic response of human skeletal muscle after exercise.

Outcomes from selective use of thrombectomy in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction: an analysis of the British Cardiovascular Intervention Society/National Institute for Cardiovascular Outcomes Research (BCIS-NICOR) registry 2006-2013
Journal Article
Mamas. (2016). Outcomes from selective use of thrombectomy in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction: an analysis of the British Cardiovascular Intervention Society/National Institute for Cardiovascular Outcomes Research (BCIS-NICOR) registry 2006-2013. JACC: Cardiovascular Interventions, 126-134. https://doi.org/10.1016/j.jcin.2015.10.047

Objectives This study used a large national cohort to examine patterns of thrombectomy use in ST-segment elevation myocardial infarction (STEMI) and the relationship to mortality. Background The impact of coronary thrombectomy on mortality in ST... Read More about Outcomes from selective use of thrombectomy in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction: an analysis of the British Cardiovascular Intervention Society/National Institute for Cardiovascular Outcomes Research (BCIS-NICOR) registry 2006-2013.

Spectropathology for the next generation: Quo vadis?
Journal Article
Byrne, H., Baranska, M., Puppels, G., Stone, N., Wood, B., Gough, K., …Sockalingum, G. (2015). Spectropathology for the next generation: Quo vadis?. Analyst, 2066-2073. https://doi.org/10.1039/C4AN02036G

Although the potential of vibrational spectroscopy for biomedical applications has been well demonstrated, translation into clinical practice has been relatively slow. This Editorial assesses the challenges facing the field and the potential way forw... Read More about Spectropathology for the next generation: Quo vadis?.

Stathmin is enriched in the developing corticospinal tract
Journal Article
Fuller, H. R., Slade, R., Jovanov-Milošević, N., Babić, M., Sedmak, G., Šimić, G., …Gates, M. A. (2015). Stathmin is enriched in the developing corticospinal tract. Molecular and Cellular Neuroscience, 12-21. https://doi.org/10.1016/j.mcn.2015.09.003

Understanding the intra- and extracellular proteins involved in the development of the corticospinal tract (CST) may offer insights into how the pathway could be regenerated following traumatic spinal cord injury. Currently, however, little is known... Read More about Stathmin is enriched in the developing corticospinal tract.