All Outputs (2258)

A realist review of medication optimisation of community dwelling service users with serious mental illness (2023)
Journal Article
Howe, J., MacPhee, M., Duddy, C., Habib, H., Wong, G., Jacklin, S., Oduola, S., Upthegrove, R., Carlish, M., Allen, K., Patterson, E., & Maidment, I. (2023). A realist review of medication optimisation of community dwelling service users with serious mental illness. BMJ Quality and Safety, https://doi.org/10.1136/bmjqs-2023-016615

Background: Severe mental illness (SMI) incorporates schizophrenia, bipolar disorder, non-organic psychosis, personality disorder or any other severe and enduring mental health illness. Medication, particularly antipsychotics and mood stabilisers are... Read More about A realist review of medication optimisation of community dwelling service users with serious mental illness.

Impact of technology interventions on technology sensitive dispensing errors (2023)
Journal Article
Hill, A., & White, S. (2023). Impact of technology interventions on technology sensitive dispensing errors. International Journal of Pharmacy Practice, 31(Supplement_2), ii24-ii25. https://doi.org/10.1093/ijpp/riad074.029

Introduction Technology has the potential to impact significantly on dispensing error rates. Technology systems are already widely established in UK hospitals such as automated dispensing systems (robots) and electronic prescribing systems. A single... Read More about Impact of technology interventions on technology sensitive dispensing errors.

Collaborating for better care (2023)
Presentation / Conference Contribution
White, S., Kellam, B., Bond, C., & Donyai, P. Collaborating for better care. Presented at The Royal Pharmaceutical Society Annual Conference, London, UK

Exploring community pharmacists’ views around HRT and the menopause (2023)
Presentation / Conference Contribution
Lakhani, S., & Allinson, M. D. Exploring community pharmacists’ views around HRT and the menopause

Introduction The number of women in England prescribed HRT has increased dramatically in the last seven years.1 Meanwhile, from 2018, HRT product shortages have resulted in the release of Serious Shortage Protocols allowing community pharmacists to s... Read More about Exploring community pharmacists’ views around HRT and the menopause.

Patient satisfaction with community pharmacy COVID-19 vaccination in Northern Ireland (2023)
Presentation / Conference Contribution
Garland, C., & Jacklin, S. Patient satisfaction with community pharmacy COVID-19 vaccination in Northern Ireland

Introduction Northern Ireland’s community pharmacies have contributed substantially to the COVID-19 response, with over 436,000 COVID-19 vaccines administered since March 2021. Community pharmacy has an established role across the UK in delivering in... Read More about Patient satisfaction with community pharmacy COVID-19 vaccination in Northern Ireland.

Polypharmacy in atrial fibrillation: A prospective analysis of mortality and ischemic stroke using the Clinical Practice Research Datalink (2023)
Journal Article
Slater, N., White, S., & Frisher, M. (2024). Polypharmacy in atrial fibrillation: A prospective analysis of mortality and ischemic stroke using the Clinical Practice Research Datalink. Journal of Arrhythmia, 40(1), 47-56. https://doi.org/10.1002/joa3.12961

Background: Observational studies of polypharmacy and the risk of death or stroke in individuals with atrial fibrillation (AF) have produced inconsistent findings. By using propensity score matching (PSM) and Cox regression, this study aimed to deter... Read More about Polypharmacy in atrial fibrillation: A prospective analysis of mortality and ischemic stroke using the Clinical Practice Research Datalink.

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., Achana, F. A., Frisher, M., Huntley, A. L., Mallen, C. D., Png, M. E., Tatton, S., White, S., & Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective
Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.

Initial Experience with the Solitaire X 3 mm Stent Retriever for the Treatment of Distal Medium Vessel Occlusions (2023)
Journal Article
Ntoulias, N., Brehm, A., Tsogkas, I., Jesser, J., Caragliano, A. A., Demerath, T., van Es, A. C. G. M., Gruber, P., Vega, P., Lüttich, A., Nayak, S., Fandiño, E., Ribo, M., Rodriguez Paz, C. M., Möhlenbruch, M. A., Tessitore, A., Remonda, L., Murias, E., Blackham, K. A., & Psychogios, M.-N. (in press). Initial Experience with the Solitaire X 3 mm Stent Retriever for the Treatment of Distal Medium Vessel Occlusions. Journal of Clinical Medicine, 12(23), 7289. https://doi.org/10.3390/jcm12237289

Endovascular therapy (EVT) is the standard treatment for ischemic stroke caused by a large vessel occlusion (LVO). The effectiveness of EVT for distal medium vessel occlusions (MDVOs) is still uncertain, but newer, smaller devices show potential for... Read More about Initial Experience with the Solitaire X 3 mm Stent Retriever for the Treatment of Distal Medium Vessel Occlusions.

Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis (2023)
Journal Article
Merfort, R., Maffulli, N., Hofmann, U. K., Hildebrand, F., Simeone, F., Eschweiler, J., & Migliorini, F. (in press). Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis. Scientific Reports, 13(1), Article 20327. https://doi.org/10.1038/s41598-023-47670-z

Total hip arthroplasty (THA) is a common procedure for patients suffering from hip pain e.g. from osteoarthritis, osteonecrosis, or hip fractures. The satisfaction of patients undergoing THA is influenced by the choice of implant type and material, w... Read More about Head, acetabular liner composition, and rate of revision and wear in total hip arthroplasty: a Bayesian network meta-analysis.

Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study (2023)
Journal Article
Schneider, J., Maffulli, N., Eschweiler, J., Bell, A., Hildebrand, F., & Migliorini, F. (in press). Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study. Scientific Reports, 13(1), Article 20210. https://doi.org/10.1038/s41598-023-47508-8

The prophylactic action of non-steroidal anti-inflammatory drugs (NSAIDs) in heterotopic ossification (HO) was first described following analgesic therapy with indomethacin. Following that evidence, several compounds have been successfully used for p... Read More about Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study.

Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction (2023)
Journal Article
Dimmock, R. L., Rotherham, M., El Haj, A. J., & Yang, Y. (in press). Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction. Gels, 9(11), Article 915. https://doi.org/10.3390/gels9110915

In the biomedical field, there is a demand for the development of novel approaches for the investigation of optical epithelial anatomical features with biomimetic materials. These materials are not only required to replicate structures but also enabl... Read More about Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction.

Artificial Intelligence and Machine Learning in Rotator Cuff Tears. (2023)
Journal Article
Rodriguez, H. C., Rust, B., Hansen, P. Y., Maffulli, N., Gupta, M., Potty, A. G., & Gupta, A. (in press). Artificial Intelligence and Machine Learning in Rotator Cuff Tears. Sports Medicine and Arthroscopy Review, 31(3), 67-72. https://doi.org/10.1097/JSA.0000000000000371

Rotator cuff tears (RCTs) negatively impacts patient well-being. Artificial intelligence (AI) is emerging as a promising tool in medical decision-making. Within AI, deep learning allows to autonomously solve complex tasks. This review assesses the cu... Read More about Artificial Intelligence and Machine Learning in Rotator Cuff Tears..

Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries. (2023)
Journal Article
Aratikatla, A., Sidhu, J., Maffulli, N., Gupta, M., Potty, A. G., & Gupta, A. (in press). Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries. Sports Medicine and Arthroscopy Review, 31(3), 73-79. https://doi.org/10.1097/JSA.0000000000000369

Highly prone to injury, the rotator cuff greatly contributes to the stability and mobility of the shoulder. Clinicians prioritize conservative treatment, resorting to surgery only when necessary, although they are hindered by inherent limitations. Bi... Read More about Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries..

EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW (2023)
Presentation / Conference Contribution
Rix, L., Tushingham, S., Wright, K., & Snow, M. EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW. Presented at The British Orthopaedic Research Society (BORS) 2023 Meeting (25–26 September 2023), Cambridge, England

AbstractObjectiveA common orthopaedic pain found in a wide spectrum of individuals, from young and active to the elderly is anterior knee pain (AKP). It is a multifactorial disorder which is thought to occur through muscular imbalance, overuse, traum... Read More about EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW.

SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS (2023)
Presentation / Conference Contribution
Wright, K., McDonald, J., Mennan, C., Perry, J., Peffers, M., & Hulme, C. SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS. Presented at The British Orthopaedic Research Society (BORS) 2023 Meeting (25–26 September 2023), Cambridge, England

AbstractObjectivesA promising therapy for early osteoarthritis (OA) is the transplantation of human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs). The synovial fluid (SF) from a pre-clinical ovine model treated with hUC-MSCs has been pr... Read More about SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS.

CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS (2023)
Presentation / Conference Contribution
Lan, T., Wright, K., Makwana, N., Bing, A., McCarthy, H., & Hulme, C. CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS. Presented at The British Orthopaedic Research Society (BORS) 2023 Meeting (25–26 September 2023), Cambridge, England

AbstractObjectivesBone marrow aspirate concentrate (BMAC), together with fibrin glue (Tisseel, Baxter, UK) and Hyaluronic acid (HA) were used as a one-step cell therapy treating patients with ankle cartilage defects in our hospital. This therapy was... Read More about CHARACTERIZING CELLULAR COMPONENTS OF BONE MARROW ASPIRATE CONCENTRATE: A ONE-STEP CELL THERAPY FOR ANKLE CARTILAGE DEFECTS.

Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid (2023)
Journal Article
Lundeen, M., Hurd, J. L., Hayes, M., Hayes, M., Facile, T. R., Furia, J. P., Maffulli, N., Alt, C., Alt, E. U., Schmitz, C., & Pearce, D. A. (in press). Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid. Scientific Reports, 13(1), 19348. https://doi.org/10.1038/s41598-023-46653-4

Symptomatic, partial-thickness rotator cuff tears (sPTRCT) are problematic. This study tested the hypothesis that management of sPTRCT with injection of fresh, uncultured, unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) is safe... Read More about Management of partial-thickness rotator cuff tears with autologous adipose-derived regenerative cells is safe and more effective than injection of corticosteroid.

CSP2023: 460 Exploring healthcare professionals' perspectives on how community pharmacy could better support people living with osteoarthritis: A qualitative interview study (2023)
Presentation / Conference
Simkins, J., White, S., Babatunde, O., & Holden, M. (2023, November). CSP2023: 460 Exploring healthcare professionals' perspectives on how community pharmacy could better support people living with osteoarthritis: A qualitative interview study. Poster presented at Chartered Society of Physiotherapy (CSP) 2023 Annual Conference, Birmingham Conference and Events Centre, Hill Street, , Birmingham, B5 4EW

Osteoarthritis (OA) is a highly prevalent and painful condition that is commonly managed in primary care by various healthcare professionals (HCPs), including physiotherapists (1). Community pharmacy staff have transferable skills that make them well... Read More about CSP2023: 460 Exploring healthcare professionals' perspectives on how community pharmacy could better support people living with osteoarthritis: A qualitative interview study.

The impact on patients of pharmacist-conducted domiciliary COPD annual reviews: a qualitative study (2023)
Thesis
Ballantyne, S. J. The impact on patients of pharmacist-conducted domiciliary COPD annual reviews: a qualitative study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/599241

Introduction
Globally, Chronic Obstructive Pulmonary Disease (COPD) is one of the most important non-communicable diseases with a progressive downhill course.1 Guidelines recommend regular review of patients with COPD.2 In the UK traditionally, ann... Read More about The impact on patients of pharmacist-conducted domiciliary COPD annual reviews: a qualitative study.

Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling (2023)
Thesis
Chen, S. Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling. (Thesis). Keele University. https://keele-repository.worktribe.com/output/598060

Fibroblast growth factors (FGFs) are polypeptide growth factors and are potent regulators of cell proliferation, cell differentiation, cell migration and angiogenesis (Ornitz and Itoh, 2001). FGFs can bind with fibroblast growth factor receptors with... Read More about Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling.