An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease
(2022)
Thesis
Earle, H. (2022). An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease. (Thesis). Keele University
Ferroptosis is a non-apoptotic, iron-dependent cell death pathway first identified in an engineered tumorigenic cell line in 2012. Hallmark characteristics include direct or indirect loss of functional GPX4 enzymes, resulting in depletion of glutathi... Read More about An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease.