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Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold (2018)
Journal Article
Dimitriou, E., Jones, R., Pritchard, R., Miller, G., & O'Brien, M. (2018). Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold. Tetrahedron, 74(47), 6795-6803. https://doi.org/10.1016/j.tet.2018.09.025

Using a Tube-in-Tube device based on the amorphous Teflon AF-2400 fluoropolymer, a series of nitroarenes was hydrogenated to afford the corresponding aniline compounds. The system was then applied to the construction of a pyrrolobenzo[1,4]diazapene s... Read More about Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold.

New occurrences of Palaeopascichnus from the Stáhpogieddi Formation, Arctic Norway, and their bearing on the age of the Varanger Ice Age (2018)
Journal Article
Jensen, S., Hogstrom, A. E. S., Hoyberget, M., Meinhold, G., McIlroy, D., Ebbestad, J. O. R., …Palacios, T. (2018). New occurrences of Palaeopascichnus from the Stáhpogieddi Formation, Arctic Norway, and their bearing on the age of the Varanger Ice Age. Canadian Journal of Earth Sciences, 55(11), 1253-1261. https://doi.org/10.1139/cjes-2018-0035

We report on new occurrences of the late Ediacaran problematicum Palaeopascichnus (Protista?) from the Stáhpogieddi Formation, Arctic Norway. The stratigraphically lowest occurrences are in beds transitional between the Lillevannet and Indreelva memb... Read More about New occurrences of Palaeopascichnus from the Stáhpogieddi Formation, Arctic Norway, and their bearing on the age of the Varanger Ice Age.

TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database (2018)
Journal Article
Kinnaird, T., Calvert, P., Anderson, R., Sirker, A., de Belder, M., Ludman, P., …Mamas, M. (2018). TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database. Journal of the American College of Cardiology, 72(13), Article B306. https://doi.org/10.1016/j.jacc.2018.08.1994

Background The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients presenting with an acute coronary syndrome (ACS-PCI) is limited with the specific role of acute pharmacology in its clinical p... Read More about TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database.

Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures (2018)
Journal Article
Summerton, E., Hollamby, M., Duff, C., Thompson, E., Snow, T., Smith, A., …Britton, M. (2018). Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures. Journal of Colloid and Interface Science, 535(1), 1-7. https://doi.org/10.1016/j.jcis.2018.09.053

Surfactant crystallisation is important in many applications in the food, consumer product and medical sectors. However, these processes are not well understood. In particular, surfactant crystallisation can be detrimental to the stability of deterge... Read More about Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures.

Widespread occurrence of squirrel adenovirus 1 in red and grey squirrels in Scotland detected by a novel real-time PCR assay (2018)
Journal Article
Wernike, K., Wylezich, C., Höper, D., Schneider, J., Lurz, P. W., Meredith, A., …Ulrich, R. G. (2018). Widespread occurrence of squirrel adenovirus 1 in red and grey squirrels in Scotland detected by a novel real-time PCR assay. Virus Research, 257, 113-118. https://doi.org/10.1016/j.virusres.2018.09.007

The Eurasian Red Squirrel (Sciurus vulgaris) is distributed throughout large parts of Europe and Asia. However, its distribution in certain regions of Europe is endangered by the invasive, non-native Grey Squirrel (Sciurus carolinensis). Adenoviruses... Read More about Widespread occurrence of squirrel adenovirus 1 in red and grey squirrels in Scotland detected by a novel real-time PCR assay.

Structural features and stability of Spanish sepiolite as a potential catalyst (2018)
Journal Article
Al-Ani, . A., Gertisser, R., & Zholobenko, V. (2018). Structural features and stability of Spanish sepiolite as a potential catalyst. Applied Clay Science, 297 -304. https://doi.org/10.1016/j.clay.2018.06.021

Abstract Sepiolite-based catalysts loaded with potassium hydroxide were prepared via the wet impregnation and ion-exchange methods and evaluated as catalysts in base-assisted reactions, such as transesterification of renewable oils. The structural fe... Read More about Structural features and stability of Spanish sepiolite as a potential catalyst.

Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study (2018)
Journal Article
Mamas. (2018). Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study. International Journal of Cardiology, 120 - 127. https://doi.org/10.1016/j.ijcard.2018.04.090

Background Routine heart failure (HF) monitoring and management is in the community but the natural course of worsening renal function (WRF) and its influence on HF prognosis is unknown. We investigated the influence of routinely monitored renal decl... Read More about Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study.

Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society) (2018)
Journal Article
Mamas, M., Nolan, J., & Rashid, M. (2018). Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society). American Journal of Cardiology, 952-960. https://doi.org/10.1016/j.amjcard.2018.06.016

Major bleeding is a common complication following percutaneous coronary intervention (PCI), although little is known about how bleeding rates have changed over time and what has driven this. We analyzed all patients undergoing PCI in England and Wale... Read More about Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society).

Recent advances in the enzymatic synthesis of sugar-nucleotides using nucleotidylyltransferases and glycosyltransferases (2018)
Journal Article
Ahmadipour, S., Beswick, L., & Miller, G. (2018). Recent advances in the enzymatic synthesis of sugar-nucleotides using nucleotidylyltransferases and glycosyltransferases. Carbohydrate Research, 469, 38 - 47. https://doi.org/10.1016/j.carres.2018.09.002

Sugar-nucleotides are imperative to carbohydrate metabolism and glycoconjugate biosynthesis. Enzymatic methods to access these key materials offer a powerful alternative to traditional chemical synthesis routes. Herein we review recent advances in th... Read More about Recent advances in the enzymatic synthesis of sugar-nucleotides using nucleotidylyltransferases and glycosyltransferases.

Physical properties and CNO abundances for high-mass stars in four main-sequence detached eclipsing binaries: V478 Cyg, AH Cep, V453 Cyg, and V578 Mon (2018)
Journal Article
Pavlovski, K., Southworth, J., & Tamajo, E. (2018). Physical properties and CNO abundances for high-mass stars in four main-sequence detached eclipsing binaries: V478 Cyg, AH Cep, V453 Cyg, and V578 Mon. Monthly Notices of the Royal Astronomical Society, 481(3), 3129 -3147. https://doi.org/10.1093/mnras/sty2516

We present ten high-precision light curves of four transits in the XO-1 planetary system, obtained using u, g, r, redshifted Ha, I and z filters. We use these to measure the physical properties, orbital ephemeris, and a transmission spectrum of the p... Read More about Physical properties and CNO abundances for high-mass stars in four main-sequence detached eclipsing binaries: V478 Cyg, AH Cep, V453 Cyg, and V578 Mon.

WASP-128b: a transiting brown dwarf in the dynamical-tide regime (2018)
Journal Article
Hodzic, V., Triaud, A. H. M. J., Anderson, D. R., Bouchy, F., Cameron, A. C., Delrez, L., …West, R. (2018). WASP-128b: a transiting brown dwarf in the dynamical-tide regime. Monthly Notices of the Royal Astronomical Society, 481(4), 5091-5097. https://doi.org/10.1093/mnras/sty2512

Massive companions in close orbits around G dwarfs are thought to undergo rapid orbital decay due to runaway tidal dissipation. We report here the discovery of WASP-128b, a brown dwarf discovered by the WASP survey transiting a G0V host on a 2.2 d or... Read More about WASP-128b: a transiting brown dwarf in the dynamical-tide regime.

Long-term testosterone therapy in type 2 diabetes is associated with reduced mortality without improvement in conventional cardiovascular risk factors (2018)
Journal Article
Hackett, G., Cole, N., Mulay, A., Strange, R. C., & Ramachandran, S. (2019). Long-term testosterone therapy in type 2 diabetes is associated with reduced mortality without improvement in conventional cardiovascular risk factors. BJU International, 123(3), 519-529. https://doi.org/10.1111/bju.14536

Objective To further characterise the beneficial impact of testosterone replacement therapy (TRT) on the association between mortality and hypogonadism (HG) in men with type 2 diabetes (T2DM). We aimed to determine firstly, if changes in cardiovascu... Read More about Long-term testosterone therapy in type 2 diabetes is associated with reduced mortality without improvement in conventional cardiovascular risk factors.

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3 (2018)
Journal Article
(2018). Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3. Nature communications, https://doi.org/10.1038/s41467-018-06096-2

Conjugation is fundamental for the acquisition of new genetic traits and the development of antibiotic resistance in pathogenic organisms. Here, we show that a hypothetical Clostridium perfringens protein, TcpK, which is encoded by the tetracycline r... Read More about Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.

Making a maths degree work for the workplace (2018)
Journal Article
(2018). Making a maths degree work for the workplace. Higher Education Pedagogies, 403-416. https://doi.org/10.1080/23752696.2018.1499420

This article will provide ideas for teaching methods that aim to provide undergraduate students with the experience of working with mathematics in a business context. These teaching methods have been employed at a mainstream U.K. university in a fina... Read More about Making a maths degree work for the workplace.

The 30 Year Search for the Compact Object in SN 1987A (2018)
Journal Article
Alp, D., Larsson, J., Fransson, C., Indebetouw, R., Jerkstrand, A., Ahola, A., …Staveley-Smith, L. (2018). The 30 Year Search for the Compact Object in SN 1987A. Astrophysical Journal, 174 -174. https://doi.org/10.3847/1538-4357/aad739

Despite more than 30 years of searching, the compact object in Supernova (SN) 1987A has not yet been detected. We present new limits on the compact object in SN 1987A using millimeter, near-infrared, optical, ultraviolet, and X-ray observations from... Read More about The 30 Year Search for the Compact Object in SN 1987A.

Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa (2018)
Journal Article
Jeffries, C. L., Lawrence, G. G., Golovko, G., Kristan, M., Orsborne, J., Spence, K., …Walker, T. (2018). Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa. Wellcome Open Research, 3(113),

Background: Wolbachia, a common insect endosymbiotic bacterium that can influence pathogen transmission and manipulate host reproduction, has historically been considered absent from the Anopheles (An.) genera, but has recently been found in An. gamb... Read More about Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa.

The dynamic role of the ilio-sacral joint in jumping frogs. (2018)
Journal Article
Collings. (2018). The dynamic role of the ilio-sacral joint in jumping frogs. Biology Letters, https://doi.org/10.1098/rsbl.2018.0367

A striking feature among jumping frogs is a sharp pelvic bend about the ilio-sacral (IS) joint, unique to anurans. Although this sagittal plane hinge has been interpreted as crucial for the evolution of jumping, its mechanical contribution has not be... Read More about The dynamic role of the ilio-sacral joint in jumping frogs..

Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale. (2018)
Journal Article
(2018). Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale. PloS one, e0202539 - ?. https://doi.org/10.1371/journal.pone.0202539

OBJECTIVES: The assessment of health care professionals' attitudes and beliefs towards musculoskeletal pain is essential because they are key determinants of their clinical practice behaviour. The Pain Attitudes and Beliefs Scale (PABS) biomedical sc... Read More about Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale..

DEDICATE: proposal for a conceptual framework to develop dementia-friendly integrated eCare support. (2018)
Journal Article
(2018). DEDICATE: proposal for a conceptual framework to develop dementia-friendly integrated eCare support. BioMedical Engineering OnLine, 121 - ?. https://doi.org/10.1186/s12938-018-0552-y

BACKGROUND: Evidence shows that the implementation of information and communication technologies (ICT) enabled services supporting integrated dementia care represents an opportunity that faces multi-pronged challenges. First, the provision of dementi... Read More about DEDICATE: proposal for a conceptual framework to develop dementia-friendly integrated eCare support..