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Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC) (2018)
Journal Article
Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., …Wilkinson, C. (2018). Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC). Trials, 19, Article 408. https://doi.org/10.1186/s13063-018-2801-6

BACKGROUND: Adalimumab, a biological treatment targeting tumour necrosis factor a, might be useful in sciatica. This paper describes the challenges faced when developing a new treatment pathway for a randomised controlled trial of adalimumab for peop... Read More about Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC).

Exploiting Inherent Instability of 2D Black Phosphorus for Controlled Phosphate Release from Blow-Spun Poly (lactide-co-glycolide) Nanofibers (2018)
Journal Article
Kamyar, N., Greenhalgh, R., Nascimento, T., Medeiros, E., Matthews, P., Nogueira, L., …Blaker, J. (2018). Exploiting Inherent Instability of 2D Black Phosphorus for Controlled Phosphate Release from Blow-Spun Poly (lactide-co-glycolide) Nanofibers. ACS Applied Nano Material, https://doi.org/10.1021/acsanm.8b00938

Efforts have been made to stabilize black phosphorus (BP) to utilize its tunable band gap and anisotropic mechanical properties. Here, the intrinsic instability of BP is exploited for controlled therapeutic ion release, namely phosphate. BP was incor... Read More about Exploiting Inherent Instability of 2D Black Phosphorus for Controlled Phosphate Release from Blow-Spun Poly (lactide-co-glycolide) Nanofibers.

Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke (2018)
Journal Article
Barlas, R. S., Loke, Y. K., Mamas, M. A., Bettencourt-Silva, J. H., Ford, I., Clark, A. B., …Myint, P. K. (2018). Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke. American Journal of Cardiology, 122(6), 1085-1090. https://doi.org/10.1016/j.amjcard.2018.05.043

The optimal regimen of antiplatelet therapy for secondary prevention in noncardioembolic ischemic stroke remains controversial. We aimed to determine which regimen was associated with the greatest reduction in adverse outcomes. We analysed prospectiv... Read More about Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke.

Ensuring appropriate assessment of deemed consent in Wales. (2018)
Journal Article
Parsons, J. A. (2018). Ensuring appropriate assessment of deemed consent in Wales. Journal of Medical Ethics, 210 - ?. https://doi.org/10.1136/medethics-2018-104935

Albertsen, in his recent article, offers an assessment of the recently introduced opt-out system for organ donation in Wales. However, he focuses on whether concerns raised prior to the enactment of the new system have been realised, rather than any... Read More about Ensuring appropriate assessment of deemed consent in Wales..

Aeroacoustic response of an array of tubes with and without bias-flow (2018)
Journal Article
Surendran, A., Heckl, M. A., Peerlings, L., Boij, S., Bodén, H., & Hirschberg, A. (2018). Aeroacoustic response of an array of tubes with and without bias-flow. Journal of Sound and Vibration, 454, 1 -16. https://doi.org/10.1016/j.jsv.2018.07.022

Heat exchangers, consisting of tube arrays in a cross-flow are a vital component of power generation systems. They are of interest from an acoustic point of view, because they can reflect, transmit and absorb an incident sound wave; in other words, t... Read More about Aeroacoustic response of an array of tubes with and without bias-flow.

A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint. (2018)
Journal Article
(2018). A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint. Pilot and Feasibility Studies, 130 - ?. https://doi.org/10.1186/s40814-018-0324-2

Background: It has been argued that true endpoints (or 'hard' endpoints) for clinical trials, which are meaningful to clinicians, researchers and patients alike, are limited to those that measure health status, survival and cost. Other endpoints are... Read More about A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint..

d13C values in archaeological 14C-AMS dated charcoals: assessing mid-Holocene climate fluctuations and human response from a high-resolution isotope record (Arslantepe, Turkey) (2018)
Journal Article
(2018). d13C values in archaeological 14C-AMS dated charcoals: assessing mid-Holocene climate fluctuations and human response from a high-resolution isotope record (Arslantepe, Turkey). Rapid Communications in Mass Spectrometry, 1149-1162. https://doi.org/10.1002/rcm.8137

RATIONALE: Past climate has always influenced human adaptation to the environment. In order to reconstruct palaeoclimate fluctuations and their role in the evolution of Near Eastern societies during the mid-Holocene, high-resolution ?13C records from... Read More about d13C values in archaeological 14C-AMS dated charcoals: assessing mid-Holocene climate fluctuations and human response from a high-resolution isotope record (Arslantepe, Turkey).

The Exoplanet Climate Infrared TElescope (EXCITE) (2018)
Journal Article
Maxted. (2018). The Exoplanet Climate Infrared TElescope (EXCITE). Proceedings of SPIE, https://doi.org/10.1117/12.2314225

Although there are a large number of known exoplanets, there is little data on their global atmospheric properties. Phase-resolved spectroscopy of transiting planets – continuous spectroscopic observation of planets during their full orbits – probes... Read More about The Exoplanet Climate Infrared TElescope (EXCITE).

Response to Comment on “An excess of massive stars in the local 30 Doradus starburst” (2018)
Journal Article
Schneider, F. R. N., Sana, H., Evans, C. J., Bestenlehner, J. M., Castro, N., Fossati, L., …Norman, C. (2018). Response to Comment on “An excess of massive stars in the local 30 Doradus starburst”. Science, 361(6400), https://doi.org/10.1126/science.aat7032

Farr and Mandel reanalyze our data, finding initial mass function slopes for high-mass stars in 30 Doradus that agree with our results. However, their reanalysis appears to underpredict the observed number of massive stars. Their technique results in... Read More about Response to Comment on “An excess of massive stars in the local 30 Doradus starburst”.

WASP 0639-32: a new F-type subgiant/K-type main-sequence detached eclipsing binary from the WASP project (2018)
Journal Article
Hellier, & Maxted. (2018). WASP 0639-32: a new F-type subgiant/K-type main-sequence detached eclipsing binary from the WASP project. Astronomy & Astrophysics, A135 - A135. https://doi.org/10.1051/0004-6361/201731435

Aims. Our aim is to measure the masses and radii of the stars in a newly-discovered detached eclipsing binary system to a high precision (˜1%), enabling the system to be used for the calibration of free parameters in stellar evolutionary models.

M... Read More about WASP 0639-32: a new F-type subgiant/K-type main-sequence detached eclipsing binary from the WASP project.

The low mass population of the Vela OB2 association from Gaia (2018)
Journal Article
Armstrong, J. J., Jeffries, R. D., & Wright, N. J. (2018). The low mass population of the Vela OB2 association from Gaia. Monthly Notices of the Royal Astronomical Society: Letters, 480(1), L121–L125. https://doi.org/10.1093/mnrasl/sly137

The first Gaia Data Release presents an opportunity to characterise the low-mass population of OB associations, providing larger statistical samples and better constraints on the formation and evolution of clusters and associations. Using previously... Read More about The low mass population of the Vela OB2 association from Gaia.

Interfacial waveforms in chiral lattices with gyroscopic spinners (2018)
Journal Article
Garau, M., Carta, G., Nieves, M., Jones, I., Movchan, N., & Movchan, A. (2018). Interfacial waveforms in chiral lattices with gyroscopic spinners. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 474(2215), https://doi.org/10.1098/rspa.2018.0132

We demonstrate a new method of achieving topologically protected states in an elastic hexagonal system of trusses by attaching gyroscopic spinners, which bring chirality to the system. Dispersive features of this medium are investigated in detail, an... Read More about Interfacial waveforms in chiral lattices with gyroscopic spinners.

Cumulative exposure to biological therapy and risk of cancer in patients with psoriasis: a meta-analysis of Psonet studies from Israel, Italy, Spain, the U.K. and Republic of Ireland (2018)
Journal Article
Garcia-Doval, I., Descalzo, M., Mason, K., Cohen, A., Ormerod, A., Gómez-García, F., …Network, T. P. (2018). Cumulative exposure to biological therapy and risk of cancer in patients with psoriasis: a meta-analysis of Psonet studies from Israel, Italy, Spain, the U.K. and Republic of Ireland. British Journal of Dermatology, 179(4), 863-871. https://doi.org/10.1111/bjd.16715

Background
Cancer risk following long‐term exposure to systemic immunomodulatory therapies in patients with psoriasis is possible.

Objectives
To assess a dose–response relationship between cumulative length of exposure to biological therapy and... Read More about Cumulative exposure to biological therapy and risk of cancer in patients with psoriasis: a meta-analysis of Psonet studies from Israel, Italy, Spain, the U.K. and Republic of Ireland.

Shared decision-making (SHARE-D) for healthy behaviour change: a feasibility study in general practice (2018)
Journal Article
Heron. (2018). Shared decision-making (SHARE-D) for healthy behaviour change: a feasibility study in general practice. British Journal of General Practice Open (BJGP Open), bjgpopen18X101517 - bjgpopen18X101517. https://doi.org/10.3399/bjgpopen18X101517

Background
Effective interventions are needed to support health behaviour change for cardiovascular disease (CVD) prevention. Decision tools encourage behaviour change but their effectiveness when used in shared decision-making with health professio... Read More about Shared decision-making (SHARE-D) for healthy behaviour change: a feasibility study in general practice.

Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). (2018)
Journal Article
Kwok, C., Mamas, M., Martinez, S., Pancholy, S., Ahmed, W., Al-Shaibi, K., …Curzen, N. (2018). Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). Scientific reports, 11156 -?. https://doi.org/10.1038/s41598-018-29303-y

It is unclear how comorbidity influences rates and causes of unplanned readmissions following percutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database who were admitted to hospital between 2010 and 2014. T... Read More about Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database)..

Infrared spectroscopy of the merger candidate KIC 9832227 (2018)
Journal Article
Pavlenko, Y., Evans, A., Banerjee, D., Southworth, J., Shahbandeh, M., & Davis, S. (2018). Infrared spectroscopy of the merger candidate KIC 9832227. Astronomy and Astrophysics, 615, Article A120. https://doi.org/10.1051/0004-6361/201832717

Context. It has been predicted that the object KIC 9832227 – a contact binary star – will undergo a merger in 2022.2±0.7.We describe the near infrared spectrum of this object as an impetus to obtain pre-merger data.
Aims. We aim to characterise (i)... Read More about Infrared spectroscopy of the merger candidate KIC 9832227.

Derivation and Validation of Risk Scores to Predict Cerebrovascular Mortality Among Incident Peritoneal Dialysis Patients (2018)
Journal Article
Yu. (2018). Derivation and Validation of Risk Scores to Predict Cerebrovascular Mortality Among Incident Peritoneal Dialysis Patients. Kidney and Blood Pressure Research, https://doi.org/10.1159/000492048

Background/Aims:
Cerebrovascular disease (CeVD) is one of the leading causes of death in patients initialising peritoneal dialysis (PD). Currently there is no risk score to predict the future risk of CeVD on entry into PD. This study aimed to derive... Read More about Derivation and Validation of Risk Scores to Predict Cerebrovascular Mortality Among Incident Peritoneal Dialysis Patients.

Exploring what patients think when answering the Interpersonal Skills Questionnaire (ISQ) following a hospital pharmacist consultation: A ‘think-aloud’ study (2018)
Journal Article
Al-Jabr, H., Twigg, M., Saadvandi, R., & Desborough, J. (2018). Exploring what patients think when answering the Interpersonal Skills Questionnaire (ISQ) following a hospital pharmacist consultation: A ‘think-aloud’ study. Research in Social and Administrative Pharmacy, 14(8), e47-e48. https://doi.org/10.1016/j.sapharm.2018.05.097

Background: The Interpersonal Skills Questionnaire (ISQ) was developed to collect patient feedback on consultation skills of practitioners. However, it has not yet been evaluated with pharmacists. Therefore, the aim of this study was to use cognitive... Read More about Exploring what patients think when answering the Interpersonal Skills Questionnaire (ISQ) following a hospital pharmacist consultation: A ‘think-aloud’ study.