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All Outputs (1412)

RCGP Research Paper of the Year 2019: impact of COVID-19 (2020)
Journal Article
Chew-Graham, C. (2020). RCGP Research Paper of the Year 2019: impact of COVID-19. British Journal of General Practice (BJGP), 70(701), 602-603. https://doi.org/10.3399/bjgp20x713777

The Research Paper of the Year (RPY), awarded by the Royal College of General Practitioners (RCGP), gives recognition to an individual or group of researchers who have undertaken and published an exceptional piece of research relating to general prac... Read More about RCGP Research Paper of the Year 2019: impact of COVID-19.

COVID-19—Zoonosis or Emerging Infectious Disease? (2020)
Journal Article
Haider, N., Rothman-Ostrow, R., Osman, A., Arruda, L., Macfarlane-Berry, L., Elton, L., …Kock, R. (2020). COVID-19—Zoonosis or Emerging Infectious Disease?. Frontiers in Public Health, 8, 1-8. https://doi.org/10.3389/fpubh.2020.596944

<jats:p>The World Health Organization defines a zoonosis as any infection naturally transmissible from vertebrate animals to humans. The pandemic of Coronavirus disease (COVID-19) caused by SARS-CoV-2 has been classified as a zoonotic disease, howeve... Read More about COVID-19—Zoonosis or Emerging Infectious Disease?.

COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey (2020)
Journal Article
Sherman, S. M., Smith, L. E., Sim, J., Amlôt, R., Cutts, M., Dasch, H., …Sevdalis, N. (2020). COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey. Human Vaccines and Immunotherapeutics, 1 - 10. https://doi.org/10.1080/21645515.2020.1846397

Aim: To investigate factors associated with intention to be vaccinated against COVID-19. Methods: Online cross-sectional survey of 1,500 UK adults, recruited from an existing online research panel. Data were collected between 14th and 17th July 2020.... Read More about COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey.

Usability and Acceptability of a Novel Secondary Prevention Initiative Targeting Physical Activity for Individuals after a Transient Ischaemic Attack or "Minor" Stroke: A Qualitative Study. (2020)
Journal Article
Heron, N., O’Connor, S. R., Kee, F., Mant, J., Cupples, M. E., & Donnelly, M. (2020). Usability and Acceptability of a Novel Secondary Prevention Initiative Targeting Physical Activity for Individuals after a Transient Ischaemic Attack or "Minor" Stroke: A Qualitative Study. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph17238788

Behavioural interventions that address cardiovascular risk factors such as physical inactivity and hypertension help reduce recurrence risk following a transient ischaemic attack (TIA) or "minor" stroke, but an optimal approach for providing secondar... Read More about Usability and Acceptability of a Novel Secondary Prevention Initiative Targeting Physical Activity for Individuals after a Transient Ischaemic Attack or "Minor" Stroke: A Qualitative Study..

A Checklist for Implementing Rural Pathways to Train, Develop and Support Health Workers in Low and Middle-Income Countries (2020)
Journal Article
Worley, P., Wynn-Jones, J., O'Sullivan, B., Chater, B., Bingham, A., Couper, I., …Strasser, S. (2020). A Checklist for Implementing Rural Pathways to Train, Develop and Support Health Workers in Low and Middle-Income Countries. Frontiers in Medicine, 594728 - ?. https://doi.org/10.3389/fmed.2020.594728

Background: There is an urgent need to scale up global action on rural workforce development. This World Health Organization-sponsored research aimed to develop a Rural Pathways Checklist. Its purpose was to guide the practical implementation of rura... Read More about A Checklist for Implementing Rural Pathways to Train, Develop and Support Health Workers in Low and Middle-Income Countries.

COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey. (2020)
Journal Article
Sherman, S., Smith, L., Sim, J., Amlôt, R., Cutts, M., Dasch, H., …Sevdalis, N. (2020). COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey. Human Vaccines and Immunotherapeutics, 1 - 10. https://doi.org/10.1080/21645515.2020.1846397

To investigate factors associated with intention to be vaccinated against COVID-19 we conducted a cross-sectional survey of 1,500 UK adults, recruited from an existing online research panel. Data were collected between 14th and 17th July 2020. We use... Read More about COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey..

COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey (2020)
Journal Article
Sherman, S., Smith, L. E., Sim, J., Amlôt, R., Cutts, M., Dasch, H., …Sevdalis, N. (2020). COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey. Human Vaccines and Immunotherapeutics, 17(6), https://doi.org/10.1080/21645515.2020.1846397

Aim: To investigate factors associated with intention to be vaccinated against COVID-19. Methods: Online cross-sectional survey of 1,500 UK adults, recruited from an existing online research panel. Data were collected between 14th and 17th July 2020.... Read More about COVID-19 vaccination intention in the UK: Results from the COVID-19 Vaccination Acceptability Study (CoVAccS), a nationally representative cross-sectional survey.

On global plasticity: framing the global through affective materiality (2020)
Journal Article
McKay. (2020). On global plasticity: framing the global through affective materiality. New Global Studies, https://doi.org/10.1515/ngs-2020-0039

As a pervasive, material element of the global, plastics raise potent social and environmental questions. More than merely the ‘stuff’ of potential global prosperity, plastics are substances people inscribe with varied cultural meanings. Deploying co... Read More about On global plasticity: framing the global through affective materiality.

Inhibition of the GDP-d-Mannose Dehydrogenase from Pseudomonas aeruginosa Using Targeted Sugar Nucleotide Probes (2020)
Journal Article
Beswick, L., Dimitriou, E., Ahmadipour, S., Zafar, A., Rejzek, M., Reynisson, J., …Miller, G. (2020). Inhibition of the GDP-d-Mannose Dehydrogenase from Pseudomonas aeruginosa Using Targeted Sugar Nucleotide Probes. ACS chemical biology, 15(12), 3086–3092. https://doi.org/10.1021/acschembio.0c00426

Sufferers of cystic fibrosis are at extremely high risk for contracting chronic lung infections. Over their lifetime, one bacterial strain in particular, Pseudomonas aeruginosa, becomes the dominant pathogen. Bacterial strains incur loss-of-function... Read More about Inhibition of the GDP-d-Mannose Dehydrogenase from Pseudomonas aeruginosa Using Targeted Sugar Nucleotide Probes.

The Right of Reply: On the Science and Politics of Crowd Psychology (2020)
Journal Article
Stott, C., Ho, L., Radburn, M., Chan, Y. T., Kyprianides, A., & Morales, P. S. (2021). The Right of Reply: On the Science and Politics of Crowd Psychology. Policing, 14(4), 852-859. https://doi.org/10.1093/police/paaa078

It is important to recognize that the publication of this study is the outcome of a pioneering approach developed by the editorial team of what has recently become one of the world’s most highly ranked policing journals. As part of their underpinning... Read More about The Right of Reply: On the Science and Politics of Crowd Psychology.

Statistical Signatures of Nanoflare Activity. II. A Nanoflare Explanation for Periodic Brightenings in Flare Stars Observed by NGTS (2020)
Journal Article
(2020). Statistical Signatures of Nanoflare Activity. II. A Nanoflare Explanation for Periodic Brightenings in Flare Stars Observed by NGTS. Astrophysical Journal, 1-18. https://doi.org/10.3847/1538-4357/abbfa8

Several studies have documented periodic and quasi-periodic signals from the time series of dMe flare stars and other stellar sources. Such periodic signals, observed within quiescent phases (i.e., devoid of larger-scale microflare or flare activity)... Read More about Statistical Signatures of Nanoflare Activity. II. A Nanoflare Explanation for Periodic Brightenings in Flare Stars Observed by NGTS.

The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction (2020)
Journal Article
Parmar, S., Mohamed, M., Wilkie, R., & Mamas, M. (2020). The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction. European Heart Journal, 41(S2), 1660 - 1660. https://doi.org/10.1093/ehjci/ehaa946.1660

Background
People with osteoarthritis (OA) have an increased risk of cardiovascular disease, including acute myocardial infarction (AMI). Despite OA being the most common joint condition and the fastest increasing major health condition, there is li... Read More about The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction.

Insecticide Resistance Profiling of Anopheles coluzzii and Anopheles gambiae Populations in the Southern Senegal: Role of Target Sites and Metabolic Resistance Mechanisms. (2020)
Journal Article
(2020). Insecticide Resistance Profiling of Anopheles coluzzii and Anopheles gambiae Populations in the Southern Senegal: Role of Target Sites and Metabolic Resistance Mechanisms. Genes, https://doi.org/10.3390/genes11121403

The emergence and spread of insecticide resistance among the main malaria vectors is threatening the effectiveness of vector control interventions in Senegal. The main drivers of this resistance in the Anopheles gambiae complex (e.g., An. gambiae and... Read More about Insecticide Resistance Profiling of Anopheles coluzzii and Anopheles gambiae Populations in the Southern Senegal: Role of Target Sites and Metabolic Resistance Mechanisms..

An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure (2020)
Journal Article
(2020). An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure. Radiology Research and Practice, 3246531 - ?. https://doi.org/10.1155/2020/3246531

Introduction: The incidence of pressure ulcers (PUs) presents a substantial threat to patients, especially geriatric patients, those with restricted mobility, and patients suffering from chronic diseases such as cancer. PUs creates a huge financial b... Read More about An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure.

Risk assessments and structured care interventions for prevention of foot ulceration in diabetes: development and validation of a prognostic model. (2020)
Journal Article
(2020). Risk assessments and structured care interventions for prevention of foot ulceration in diabetes: development and validation of a prognostic model. Health Technology Assessment, 1 - 198. https://doi.org/10.3310/hta24620

BACKGROUND: Diabetes-related foot ulcers give rise to considerable morbidity, generate a high monetary cost for health and social care services and precede the majority of diabetes-related lower extremity amputations. There are many clinical predicti... Read More about Risk assessments and structured care interventions for prevention of foot ulceration in diabetes: development and validation of a prognostic model..

Optimising the assessment and management of lower limb wounds in general practice (2020)
Journal Article
Green. (2020). Optimising the assessment and management of lower limb wounds in general practice. Primary Health Care, https://doi.org/10.7748/phc.2020.e1673

Patients who present to general practice with a complex lower limb wound or vascular concerns are often referred to other services for review, which may cause delays to their assessment and treatment. To provide prompt assessment and management for p... Read More about Optimising the assessment and management of lower limb wounds in general practice.

characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons (2020)
Journal Article
Singh, A., Chow, O., Jenkins, S., Zhu, L., Rose, E., Astbury, K., & Chen, R. (2021). characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons. Neuroscience, 453, Article 17-31. https://doi.org/10.1016/j.neuroscience.2020.11.008

Preconditioning tissue with sublethal ischaemia or hypoxia can confer tolerance (protection) against subsequent ischaemic challenge. In vitro ischaemic preconditioning (IPC) is typically achieved through oxygen glucose deprivation (OGD), whereas hypo... Read More about characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons.

Syndecan-3 regulates MSC adhesion, ERK and AKT signalling in vitro and its deletion enhances MSC efficacy in a model of inflammatory arthritis in vivo (2020)
Journal Article
Jones, F. K., Stefan, A., Kay, A. G., Hyland, M., Morgan, R., Forsyth, N. R., …Kehoe, O. (2020). Syndecan-3 regulates MSC adhesion, ERK and AKT signalling in vitro and its deletion enhances MSC efficacy in a model of inflammatory arthritis in vivo. Scientific reports, https://doi.org/10.1038/s41598-020-77514-z

Rheumatoid arthritis (RA) is a debilitating and painful inflammatory autoimmune disease characterised by the accumulation of leukocytes in the synovium, cartilage destruction and bone erosion. The immunomodulatory effects of bone marrow derived mesen... Read More about Syndecan-3 regulates MSC adhesion, ERK and AKT signalling in vitro and its deletion enhances MSC efficacy in a model of inflammatory arthritis in vivo.