Skip to main content

Research Repository

Advanced Search

All Outputs (26)

A service-user digital intervention to collect real-time safety information on acute, adult mental health wards: the WardSonar mixed-methods study. (2024)
Report
Baker, J., Kendal, S., Bojke, C., Louch, G., Halligan, D., Shafiq, S., …Vincent, C. (2024). A service-user digital intervention to collect real-time safety information on acute, adult mental health wards: the WardSonar mixed-methods study. NIHR

Background
Acute inpatient mental health services report high levels of safety incidents. The application of patient safety theory has been sparse, particularly concerning interventions that proactively seek patient perspectives.

Objective(s)
De... Read More about A service-user digital intervention to collect real-time safety information on acute, adult mental health wards: the WardSonar mixed-methods study..

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Report
Sahota, O., Narayanasamy, M., Bastounis, A., Paskins, Z., Bishop, S., Langley, T., …Leonardi-Bee, J. (2024). Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study. Secretary of State for Health and Social Care / NIHR

Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosphonates are a... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.

Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort (2023)
Report
Williamson, E., Sanchez-Santos, M. T., Marian, I. R., Maredza, M., Srikesavan, C., Garrett, A., …Lamb, S. E. (2023). Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort. NIHR

Background Back pain frequently affects older people. Knowledge about back pain in older people and evidence to inform clinical care was lacking, particularly for older people with neurogenic claudication due to spinal stenosis, which is a debilitati... Read More about Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort.

Digital health and inpatient palliative care: a cohort-controlled study (2023)
Report
Singh, B. M., Kumari-Dewat, N., Ryder, A., Parry, E., Klaire, V., Matthews, D., …Warren, K. (2023). Digital health and inpatient palliative care: a cohort-controlled study. BMJ

Objectives End of life has unacceptable levels of hospital admission and death. We aimed to determine the association of a novel digital specific system (Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life, PRADA) to modify... Read More about Digital health and inpatient palliative care: a cohort-controlled study.

One versus three weeks hypofractionated whole breast radiotherapy for early breast cancer treatment: the FAST-Forward phase III RCT (2023)
Report
Brunt, A., Haviland, J. S., Wheatley, D. A., Sydenham, M. A., Bloomfield, D. J., Chan, C., …Bliss, J. M. (2023). One versus three weeks hypofractionated whole breast radiotherapy for early breast cancer treatment: the FAST-Forward phase III RCT

FAST-Forward aimed to identify a 5-fraction schedule of adjuvant radiotherapy delivered in 1 week that was non-inferior in terms of local cancer control and as safe as the standard 15-fraction regimen after primary surgery for early breast cancer. Pu... Read More about One versus three weeks hypofractionated whole breast radiotherapy for early breast cancer treatment: the FAST-Forward phase III RCT.

Non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings: the COMPARE systematic mapping review (2021)
Report
Baker, J., Berzins, K., Canvin, K., Benson, I., Kellar, I., Wright, J., …Stewart, D. (2021). Non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings: the COMPARE systematic mapping review. National Institute for Health Research (NIHR) - Health Services and Delivery Research (HS&DR) Programme

Objectives
The study aimed to provide a mapping review of non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings; classify intervention components using the behaviour change technique taxonomy; ex... Read More about Non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings: the COMPARE systematic mapping review.

Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study (2019)
Report
Burroughs, H., Bartlam, B., Bullock, P., Lovell, K., Ogollah, R., Ray, M., …Chew-Graham, C. (2019). Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study. NIHR

BACKGROUND:Anxiety and depression often coexist in older people. These disorders are often underdiagnosed and undertreated, and are associated with increased use of health and social care services, and raised mortality. Barriers to diagnosis include... Read More about Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study.

The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study (2019)
Report
Prior, J., Muller, S., Helliwell, T., Hider, S., Barraclough, K., Dasgupta, B., & Mallen, C. (2019). The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study

We aimed to examine the association between pain, stiffness and fatigue in newly diagnosed polymyalgia rheumatica (PMR) patients using baseline data from a prospective cohort study. Fatigue is a known, but often ignored symptom of PMR. Newly diagnose... Read More about The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study.

‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis (2019)
Report
Parry, E., Ogollah, R., & Peat, G. (2019). ‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis

Objective
To determine the natural history of flare-ups in knee osteoarthritis and their relation to physical exposures.

Design
Adults aged =45 years with a recent primary care consultation for knee OA/arthralgia completed a daily pen-and-paper... Read More about ‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis.

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Report
Hay, E., Dziedzic, K., Foster, N., Peat, G., van der Windt, D., Bartlam, B., …Croft, P. (2018). Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials. NIHR. PGfAR as project number RP-PG-0407-10386. Secretary of State for Health and Social Care

<jats:sec id="abs1-1"> <jats:title>Background</jats:title> <jats:p>Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based intervent... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Looking into listening: Using eye-tracking to establish the cognitive validity of the Aptis Listening Test (2017)
Report
Holzknecht, F., Eberharter, K., Kremmel, B., Zehentner, M., McCray, G., Konrad, E., & Spöttl, C. (2017). Looking into listening: Using eye-tracking to establish the cognitive validity of the Aptis Listening Test. British Council

This study investigated the cognitive processing of 30 test-takers while completing the Aptis Listening Test. The research studied test-takers’ processes according to ones targeted at the different item
levels in the Aptis Test.

Specifically, it... Read More about Looking into listening: Using eye-tracking to establish the cognitive validity of the Aptis Listening Test.

Looking into listening (2017)
Report
Holzknecht, F., Eberharter, K., Kremmel, B., Zehentner, M., McCray, G., Konrad, E., & Spöttl, C. (2017). Looking into listening. British Council

CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness (2017)
Report
Bosanquet, K., Adamson, J., Atherton, K., Bailey, D., Baxter, C., Beresford-Dent, J., …Gilbody, S. (in press). CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness. NIHR

Background
Depression in older adults is common and is associated with poor quality of life, increased morbidity and early mortality, and increased health and social care use. Collaborative care, a low-intensity intervention for depression that is s... Read More about CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness.

Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study. (2016)
Report
Ahmed, N., Prior, J., Chen, Y., Hayward, R., Mallen, C., & Hider, S. (2016). Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study

The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care against matched cohorts. Matched retrospecti... Read More about Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study..

Community-based exercise and physical activity programmes led by exercise professionals for osteoarthritis (2016)
Report
Walsh, N., Jordan, J., Babatunde, O., Powell, J., & Healey, E. (2016). Community-based exercise and physical activity programmes led by exercise professionals for osteoarthritis

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the benefits and harms of community-based exercise and physical activity programmes led by non-healthcare exercise professionals for osteoarthriti... Read More about Community-based exercise and physical activity programmes led by exercise professionals for osteoarthritis.

Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial (2016)
Report
Richards, D. A., Bower, P., Chew-Graham, C., Gask, L., Lovell, K., Cape, J., …Russell, A. Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial. Medical Research Council, HTA, NIHR

Background
Collaborative care is effective for depression management in the USA. There is little UK evidence on its clinical effectiveness and cost-effectiveness.

Objective
To determine the clinical effectiveness and cost-effectiveness of collab... Read More about Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial.

A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial (2015)
Report
Littlewood, E., Duarte, A., Hewitt, C., Knowles, S., Palmer, S., Walker, S., …Team, R. (2015). A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial. NIHR

Background
Computerised cognitive behaviour therapy (cCBT) has been developed as an efficient form of therapy delivery with the potential to enhance access to psychological care. Independent research is needed which examines both the clinical effect... Read More about A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial.