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All Outputs (12)

Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols (2024)
Working Paper
Butt, S. E., Kepski, K., Sotiropoulos, J., & Moran, W. J. Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols

A change in mechanism was observed in the hypervalent iodine mediated cyclization of N-alkenylamides when the carbon chain between the alkene and the amide increased from two to three atoms. In the latter case, cyclization at the amide nitrogen to fo... Read More about Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols.

DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS (2024)
Working Paper
Ansumana, R., Bockarie, A. S., Konneh, M., Haider, N., Cadmus, E., Korvah, A., …Alders, R. DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS

Background Outbreaks of infectious diseases like Ebola virus disease, Lassa fever, and COVID-19 have severely strained infrastructural systems and social services across West Africa. We investigated the disruptions caused by emerging outbreaks on acc... Read More about DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS.

Protocol for the development and validation of a Rheumatoid Arthritis PredIction moDel using primary care health records (RAPID) (2024)
Working Paper
Hammond, B., Baranskaya, A., Adderley, N., Zemedikun, D., d’Elia, A., Falahee, M., …Raza, K. Protocol for the development and validation of a Rheumatoid Arthritis PredIction moDel using primary care health records (RAPID)

Background Rheumatoid Arthritis (RA) is a chronic rheumatological condition which causes inflammation of both the joint lining and extra-articular sites. It affects around 1% of the UK population and, if not properly treated, can lead joint damage, d... Read More about Protocol for the development and validation of a Rheumatoid Arthritis PredIction moDel using primary care health records (RAPID).

Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh (2024)
Working Paper
Nayeem Hasan, M., Rahman, M., Fahim Uddin, M., Ali Akbar Ashrafi, S., Rahman, K. M., Kumar Paul, K., …Haider, N. Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh

In 2023, Bangladesh experienced its largest and deadliest outbreak of Dengue virus (DENV), reporting the highest-ever recorded annual cases and deaths. We aimed to characterize the geographical transmission of the DENV in Bangladesh. From 1 Jan – 31... Read More about Shifting Geographical Transmission Patterns: Characterizing the 2023 Fatal Dengue Outbreak in Bangladesh.

UKRN Open Research Training Resources and Priorities Working Paper (2023)
Working Paper
Grange, J. A., De'Bell, H., Munafo, M., Stafford, T., Partridge, A., & Jacobs, N. UKRN Open Research Training Resources and Priorities Working Paper

UKRN Open Research Programme has released its first working paper about training priorities and resources aimed at accelerating the uptake of high quality open research practices.

Income diversification and household welfare in Tanzania 2008–2013 (2020)
Working Paper
Khan, R., & Morrissey, O. Income diversification and household welfare in Tanzania 2008–2013

This paper uses three waves of Tanzanian National Panel Surveys (2008/09, 2010/11, and 2012/13) to construct a panel from 3,676 households that appear in at least two waves to explore the effect of income diversification on household welfare measured... Read More about Income diversification and household welfare in Tanzania 2008–2013.

Black hole inconsistencies? (2020)
Working Paper
Austin, J. Black hole inconsistencies?

For large enough astrophysical objects, internal pressures are insufficient to prevent gravitational collapse to sizes smaller than a critical radius where the magnitude of escape velocity is equal to the speed of light. In coordinates natural for di... Read More about Black hole inconsistencies?.

Improved CRISPR-based suppression gene drives mitigate resistance and impose a large reproductive load on laboratory-contained mosquito populations (2020)
Working Paper
Hammond, A. M., Kyrou, K., Gribble, M., Karlsson, X., Morianou, I., Galizi, R., …Nolan, T. Improved CRISPR-based suppression gene drives mitigate resistance and impose a large reproductive load on laboratory-contained mosquito populations

Abstract CRISPR-based genes drives bias their own inheritance and can be used to modify entire populations of insect vectors of disease as a novel form of sustainable disease control. Gene drives designed to interfere with female fertility can suppre... Read More about Improved CRISPR-based suppression gene drives mitigate resistance and impose a large reproductive load on laboratory-contained mosquito populations.