All Outputs (574)

Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. (2020)
Journal Article
Mamas, M. (2020). Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. https://doi.org/10.1002/ccd.29110

OBJECTIVES: We performed a systematic review and meta-analysis to evaluate the early and midterm outcomes of patients who underwent surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG) against patients who had transcath... Read More about Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis..

Red flags in cardiac amyloidosis. (2020)
Journal Article
Mamas, M., Shing Kwok, C., & Farzaneh-Far, A. (2020). Red flags in cardiac amyloidosis. European Journal of Preventive Cardiology, 1804 - 1805. https://doi.org/10.1177/2047487319884371

Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort. (2020)
Journal Article
Mamas. (2020). Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort. Circulation: Cardiovascular Interventions, e009654 - ?. https://doi.org/10.1161/CIRCINTERVENTIONS.120.009654

BACKGROUND: The objective of the study was to evaluate changes in percutaneous coronary intervention (PCI) practice in England by analyzing procedural numbers, changes in the clinical presentation, and characteristics of patients and their clinical o... Read More about Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England: Insights From the British Cardiovascular Intervention Society PCI Database Cohort..

Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis. (2020)
Journal Article
Rashid, & Mamas. (2020). Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis. Journal of Cardiovascular Medicine, 897-904. https://doi.org/10.2459/JCM.0000000000001110

BACKGROUND: The management of patients with severe but asymptomatic aortic stenosis is challenging. Evidence on early aortic valve replacement (AVR) versus symptom-driven intervention in these patients is unknown. METHODS: Electronic databases were s... Read More about Early intervention or watchful waiting for asymptomatic severe aortic valve stenosis: a systematic review and meta-analysis..

Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. (2020)
Journal Article
Dunn. (2020). Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. Clinical Journal of Pain, https://doi.org/10.1097/AJP.0000000000000879

OBJECTIVES: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics and clinical course of low back-related leg pain patients with... Read More about Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain..

Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine (2020)
Journal Article
Farooq. (2020). Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine. https://doi.org/10.12669/pjms.36.7.3606

Background and Objectives: Stigma around COVID-19 is a major barrier in global efforts to control the COVID 19 pandemic. Limited data is available regarding stigma faced by COVID-19 patients in low- and middle-income countries (LMIC).... Read More about Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine.

Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis (2020)
Journal Article
Mamas. (2020). Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis. Expert Review of Cardiovascular Therapy, https://doi.org/10.1080/14779072.2021.1845143

Objectives: Intravascular lithotripsy (IVL) clinical efficacy and safety in the treatment of calcified coronary artery disease (CAC) is not well known. We sought to assess IVL safety and efficacy in CAC.

Methods: A comprehensive online databases s... Read More about Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis.

Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes (2020)
Journal Article
Mohamed, M., Rashid, M., Farooq, S., Siddiqui, N., Parwani, P., Shiers, D., …Mamas, M. (2020). Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes. European Heart Journal, 41(Supplement_2), https://doi.org/10.1093/ehjci/ehaa946.3146

Background
Severe mental illness (SMI) is associated with an increased risk of cardiovascular disease and mortality. However, it is unclear whether SMI patients are just as likely to receive guideline-recommended therapy for AMI as those without men... Read More about Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes.

Gout flares and health-related quality of life in people living with gout: a prospective cohort study in primary care (2020)
Thesis
Watson, L. (2020). Gout flares and health-related quality of life in people living with gout: a prospective cohort study in primary care. (Thesis). Keele University

Background
Gout is a common inflammatory arthritis affecting an estimated 2.5% of the UK population. The hallmark of gout is sudden onset, extremely painful acute inflammatory flares, which are strongly associated with impaired health-related qualit... Read More about Gout flares and health-related quality of life in people living with gout: a prospective cohort study in primary care.

Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework. (2020)
Journal Article
Swaithes, L., Dziedzic, K., Finney, A., Cottrell, E., Jinks, C., Mallen, C., …Paskins, Z. (2020). Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework. Implementation Science, 15, Article 95. https://doi.org/10.1186/s13012-020-01055-2

BACKGROUND: Osteoarthritis is a leading cause of pain and disability worldwide. Despite research supporting best practice, evidence-based guidelines are often not followed. Little is known about the implementation of non-surgical models of care in ro... Read More about Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework..

Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change (2020)
Journal Article
Porat, T., Nyrup, R., Calvo, R. A., Paudyal, P., & Ford, E. (2020). Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change. Frontiers in Public Health, https://doi.org/10.3389/fpubh.2020.573397

Background: The current COVID-19 pandemic requires sustainable behavior change to mitigate the impact of the virus. A phenomenon which has arisen in parallel with this pandemic is an infodemic—an over-abundance of information, of which some is accura... Read More about Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change.

Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study (2020)
Journal Article
Ihama, F., Pandyan, A., & Roffe, C. (2020). Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study. European Geriatric Medicine, 12, 79-89. https://doi.org/10.1007/s41999-020-00383-2

Background
Fragility fractures are common in care home residents but established tools have not been tested in this population. Aim: To identify the most practicable tool for use.

Methods
Design
Multicentre prospective observational cohort pilo... Read More about Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study.

Strategic plan for integrated care of patients with kidney failure (2020)
Journal Article
Harris, D. C., Davies, S. J., Finkelstein, F. O., Jha, V., Bello, A. K., Brown, M., …Working Groups, S. P. (2020). Strategic plan for integrated care of patients with kidney failure. Kidney International, 98(5), S117-S134. https://doi.org/10.1016/j.kint.2020.07.023

Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors. (2020)
Journal Article
Mamas. (2020). Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors. Journal of the American College of Cardiology, 1919 - 1930. https://doi.org/10.1016/j.jacc.2020.08.062

BACKGROUND: Clinical trials change practice in cardiology, and leading them requires research training, mentorship, sponsorship, and networking. Women report challenges in obtaining these opportunities. OBJECTIVES: The purpose of this review was to e... Read More about Characteristics of Heart Failure Trials Associated With Under-Representation of Women as Lead Authors..

Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. (2020)
Journal Article
Hind, D., Drabble, S., Arden, M., Mandefield, L., Waterhouse, S., Maguire, C., …O'Cathain, A. (2020). Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. BMJ Open, e039089 - ?. https://doi.org/10.1136/bmjopen-2020-039089

OBJECTIVES: To undertake a process evaluation of an adherence support intervention for people with cystic fibrosis (PWCF), to assess its feasibility and acceptability. SETTING: Two UK cystic fibrosis (CF) units. PARTICIPANTS: Fourteen adult PWCF; thr... Read More about Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation..

Health and well-being issues of Nepalese migrant workers in the Gulf Cooperation Council countries and Malaysia: a systematic review (2020)
Journal Article
Paudyal, P., Kulasabanathan, K., Cassell, J. A., Memon, A., Simkhada, P., & Prasad Wasti, S. (2020). Health and well-being issues of Nepalese migrant workers in the Gulf Cooperation Council countries and Malaysia: a systematic review. BMJ Open, e038439 - e038439. https://doi.org/10.1136/bmjopen-2020-038439

<jats:sec><jats:title>Objective</jats:title><jats:p>To summarise the evidence on health and well-being of Nepalese migrant workers in the Gulf Cooperation Council (GCC) countries and Malaysia.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:tit... Read More about Health and well-being issues of Nepalese migrant workers in the Gulf Cooperation Council countries and Malaysia: a systematic review.

Clinical prediction models to predict the risk of multiple binary outcomes: a comparison of approaches. (2020)
Journal Article
(2020). Clinical prediction models to predict the risk of multiple binary outcomes: a comparison of approaches. Statistics in Medicine, https://doi.org/10.1002/sim.8787

Clinical prediction models (CPMs) can predict clinically relevant outcomes or events. Typically, prognostic CPMs are derived to predict the risk of a single future outcome. However, there are many medical applications where two or more outcomes are o... Read More about Clinical prediction models to predict the risk of multiple binary outcomes: a comparison of approaches..

Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines (2020)
Presentation / Conference
Ahmad, I., Chufal, K. S., Bhatt, C. P., Bajpai, R., Miller, A., Chowdhary, R. L., …Gairola, M. (2020, October). Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines. Poster presented at Global Oncology: The ASTRO Annual Meeting

Purpose/Objective(s)
This study investigates the performance of treatment planning methods stratified by established target delineation guidelines in patients undergoing whole-breast radiotherapy after breast conservation surgery, based on an object... Read More about Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines.

Pathological Response Prediction To Neo-Adjuvant Chemoradiation In Esophageal Carcinoma Using Artificial Intelligence And Radiomics: An Exploratory Analysis (2020)
Presentation / Conference
Chufal, K. S., Ahmad, I., Bajpai, R., Miller, A., Chowdhary, R. L., & Gairola, M. (2020, October). Pathological Response Prediction To Neo-Adjuvant Chemoradiation In Esophageal Carcinoma Using Artificial Intelligence And Radiomics: An Exploratory Analysis. Poster presented at Global Oncology: The ASTRO Annual Meeting

Purpose/Objective(s)
To utilize Artificial Neural Networks (ANN) to predict pathological response after neoadjuvant chemoradiation (NACRT), based on Radiomics data extracted from pre-NACRT Computed Tomography (CT) datasets.

Materials/Methods
Bet... Read More about Pathological Response Prediction To Neo-Adjuvant Chemoradiation In Esophageal Carcinoma Using Artificial Intelligence And Radiomics: An Exploratory Analysis.

Bone biopsy results in patients with a history of malignancy: a case series of 378 patients (2020)
Journal Article
Morris, R., Shepherd, K., Cribb, G., Singh, J., Tyrrell, P., & Cool, P. (2021). Bone biopsy results in patients with a history of malignancy: a case series of 378 patients. Skeletal Radiology, 50(6), 1111-1116. https://doi.org/10.1007/s00256-020-03652-0

Objective
The value of a bone biopsy in patients who present with a bone lesion and past medical history of malignancy is uncertain. The objective of this study was to evaluate the outcome of bone biopsies in patients with a history of a malignancy... Read More about Bone biopsy results in patients with a history of malignancy: a case series of 378 patients.