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Comparing of reliability, construct validity and responsiveness of the IPAQ-SF and pase in adults with osteoarthritis (2020)
Journal Article
Smith, R., Dziedzic, K., Quicke, J., McHugh, G., & Healey, E. (2020). Comparing of reliability, construct validity and responsiveness of the IPAQ-SF and pase in adults with osteoarthritis. Osteoarthritis and Cartilage, 28(S1), S428. https://doi.org/10.1016/j.joca.2020.02.663

Purpose: Physical activity (PA) is recommended as a core treatment for all adults with osteoarthritis (OA), yet actual levels of physical activity in this population are low. Valid and reliable measures of PA levels that are responsive to change in a... Read More about Comparing of reliability, construct validity and responsiveness of the IPAQ-SF and pase in adults with osteoarthritis.

Adherence to Pre-operative Exercise and the Response to Prehabilitation in Oesophageal Cancer Patients (2020)
Journal Article
Halliday, L. J., Doganay, E., Wynter-Blyth, V., Osborn, H., Buckley, J., & Moorthy, K. (2021). Adherence to Pre-operative Exercise and the Response to Prehabilitation in Oesophageal Cancer Patients. Journal of Gastrointestinal Surgery, 25(4), 890-899. https://doi.org/10.1007/s11605-020-04561-2

BACKGROUND: Prehabilitation is thought to reduce post-operative respiratory complications by optimising fitness before surgery. This prospective, single-centre study aimed to establish the effect of pre-operative exercise on cardiorespiratory fitness... Read More about Adherence to Pre-operative Exercise and the Response to Prehabilitation in Oesophageal Cancer Patients.

Qualitative findings from the Hip Injection Trial (HIT): experiences of living with hip osteoarthritis and receiving trial treatments (2020)
Journal Article
Paskins, Holden, Mallen, Jinks, Hawarden, & Roddy. (2020). Qualitative findings from the Hip Injection Trial (HIT): experiences of living with hip osteoarthritis and receiving trial treatments. Rheumatology, https://doi.org/10.1093/rheumatology/keaa111.125

Background The HIT trial compared ultrasound-guided intra-articular hip injection (USGI) of triamcinolone acetonide and 1% lidocaine hydrochloride combined with best current treatment (BCT) with (i) BCT alone and (ii) an USGI of 1% lidocaine only co... Read More about Qualitative findings from the Hip Injection Trial (HIT): experiences of living with hip osteoarthritis and receiving trial treatments.

The relationship between obesity and outcomes in patients with polymyalgia rheumatica (2020)
Presentation / Conference
Scott, I. C., Bajpai, R., Mallen, C., Muller, S., Helliwell, T., & Hider, S. (2020, April). The relationship between obesity and outcomes in patients with polymyalgia rheumatica. Presented at British Society for Rheumatology Annual Conference 2020, Scottish Event Campus (SEC), Scotland, UK

Background Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about The relationship between obesity and outcomes in patients with polymyalgia rheumatica.

THERAPISTS ACCEPTABILITY OF DELIVERING A PSYCHOLOGICALLY INFORMED GAIT REHABILITATION INTERVENTION IN EARLY RHEUMATOID ARTHRITIS (GREAT): A QUALITATIVE INTERVIEW STUDY (2020)
Journal Article
Hider. (2020). THERAPISTS ACCEPTABILITY OF DELIVERING A PSYCHOLOGICALLY INFORMED GAIT REHABILITATION INTERVENTION IN EARLY RHEUMATOID ARTHRITIS (GREAT): A QUALITATIVE INTERVIEW STUDY. Rheumatology, https://doi.org/10.1093/rheumatology/keaa111.103

Background Great Strides is a brief psychologically informed gait rehabilitation intervention (two compulsory face-to-face sessions and up to four optional sessions delivered over 3 months) aimed at improving lower limb function for adults with earl... Read More about THERAPISTS ACCEPTABILITY OF DELIVERING A PSYCHOLOGICALLY INFORMED GAIT REHABILITATION INTERVENTION IN EARLY RHEUMATOID ARTHRITIS (GREAT): A QUALITATIVE INTERVIEW STUDY.

Undertaking an integrated nurse led review (INCLUDE) for patients with inflammatory conditions: does it change management of morbidities? (2020)
Journal Article
Healey, E., Chew-Graham, C., Finney, A., Cooke, K., Wathall, S., Mallen, C., …Jinks, C. (2020). Undertaking an integrated nurse led review (INCLUDE) for patients with inflammatory conditions: does it change management of morbidities?. Rheumatology, https://doi.org/10.1093/rheumatology/keaa111.141

Background People with inflammatory rheumatological conditions (IRCs), including rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), are at an increased risk... Read More about Undertaking an integrated nurse led review (INCLUDE) for patients with inflammatory conditions: does it change management of morbidities?.

Trajectories of foot pain severity over seven years and relationship to potential prognostic factors: the clinical assessment study of the foot (2020)
Journal Article
Marshall, M., Bucknall, M., Rathod-Mistry, T., Thomas, M. J., Edwards, J. J., Peat, G., …Roddy, E. (2020). Trajectories of foot pain severity over seven years and relationship to potential prognostic factors: the clinical assessment study of the foot. Rheumatology, 59(S2), https://doi.org/10.1093/rheumatology/keaa111.060

Background Foot pain is common and disabling in older adults however little is known about its course. The objective of this study was to identify foot pain trajectories over seven years and examine the associations between progressive symptom traje... Read More about Trajectories of foot pain severity over seven years and relationship to potential prognostic factors: the clinical assessment study of the foot.

Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials (2020)
Journal Article
Van Der Windt, Healey, & Holden. (2020). Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2020.02.263

Meta-analyses of randomised controlled trials (RCTs) of exercise interventions in people with knee and hip osteoarthritis (OA) provide strong evidence of, on average, a small-to-medium effect on pain and function outcomes compared to comparison inter... Read More about Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials.

CLINICAL AND COST-EFFECTIVENESS OF ULTRASOUND-GUIDED INTRA-ARTICULAR CORTICOSTEROID AND LOCAL ANAESTHETIC INJECTION FOR HIP OSTEOARTHRITIS: A RANDOMISED CONTROLLED TRIAL (HIT) (2020)
Journal Article
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2020). CLINICAL AND COST-EFFECTIVENESS OF ULTRASOUND-GUIDED INTRA-ARTICULAR CORTICOSTEROID AND LOCAL ANAESTHETIC INJECTION FOR HIP OSTEOARTHRITIS: A RANDOMISED CONTROLLED TRIAL (HIT). Osteoarthritis and Cartilage, 28(S1), https://doi.org/10.1016/j.joca.2020.02.751

Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults (2020)
Journal Article
Clarke, G. R., Thomas, M. J., Rathod-Mistry, T., Marshall, M., Menz, H. B., Peat, G., & Roddy, E. (2020). Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults. Musculoskeletal Care, 18(3), 383-390. https://doi.org/10.1002/msc.1472

BACKGROUND: Hallux valgus (HV) is a common disabling condition affecting 36% of adults aged 65 years and over. Identifying whether the severity of the deformity alters weight-bearing patterns during walking may assist clinicians optimize offloading i... Read More about Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults.

Institutional use of National Clinical Audits by healthcare providers (2020)
Journal Article
Mamas. (2020). Institutional use of National Clinical Audits by healthcare providers. Journal of Evaluation in Clinical Practice, https://doi.org/10.1111/jep.13403

Abstract Rationale, aims, and objectives Healthcare systems worldwide devote significant resources towards collecting data to support care quality assurance and improvement. In the United Kingdom, National Clinical Audits are intended to contribute t... Read More about Institutional use of National Clinical Audits by healthcare providers.

Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT (2020)
Journal Article
Diala, I., Shiohama, Y., Fujita, T., Kotake, Y., Demonacos, C., Krstic-Demonacos, M., …Fujii, M. (2020). Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT. Nucleosides, Nucleotides and Nucleic Acids, 39(1-3), 407 - 425. https://doi.org/10.1080/15257770.2020.1713357

Telomerase activity has been regarded as a critical step in cellular immortalization and carcinogenesis and because of this, regulation of telomerase represents an attractive target for anti-tumor specific therapeutics. Recently, one avenue of cancer... Read More about Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.

Magmatic and metasomatic effects of magma-carbonate interaction recorded in calc-silicate xenoliths from Merapi volcano (Indonesia) (2020)
Journal Article
Halama, R., Gertisser, R., Whitley, S., Preece, K., Deegan, F., & Troll, V. (2020). Magmatic and metasomatic effects of magma-carbonate interaction recorded in calc-silicate xenoliths from Merapi volcano (Indonesia). Journal of Petrology, https://doi.org/10.1093/petrology/egaa048

Magma-carbonate interaction is an increasingly recognised process occurring at active volcanoes worldwide, with implications for the magmatic evolution of the host volcanic systems, their eruptive behaviour, volcanic CO2 budgets, and economic mineral... Read More about Magmatic and metasomatic effects of magma-carbonate interaction recorded in calc-silicate xenoliths from Merapi volcano (Indonesia).

Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice (2020)
Journal Article
Bowerman, Ahlskog, N., Hayler, D., Krueger, A., Kubinski, S., Claus, P., …Bowerman, M. (2020). Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice. Gene Therapy, 27, 505–515. https://doi.org/10.1038/s41434-020-0146-8

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of the survival motor neuron (SMN) gene. While there are currently two approved gene-based therapies for SMA, availability, high cost, and differences in patient response indicat... Read More about Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice.

Policing the Coronavirus Outbreak: Processes and Prospects for Collective Disorder (2020)
Journal Article
Stott. (2020). Policing the Coronavirus Outbreak: Processes and Prospects for Collective Disorder. Policing, https://doi.org/10.1093/police/paaa014

This briefing is divided into three parts. First, we outline the factors which lead to incidents of collective disorder (or riots). Secondly, we consider how the overall response to the coronavirus outbreak and the role of the police within this resp... Read More about Policing the Coronavirus Outbreak: Processes and Prospects for Collective Disorder.

Managing work participation for people with rheumatic and musculoskeletal diseases. (2020)
Journal Article
Wilkie, R., & Lynch, M. (2020). Managing work participation for people with rheumatic and musculoskeletal diseases. https://doi.org/10.1016/j.berh.2020.101517

Improving work participation for individuals with rheumatic and musculoskeletal diseases (RMDs), has gained increasing interest over the last 10 years. New approaches are based upon increasing adoption of a biopsychosocial approach to improving work... Read More about Managing work participation for people with rheumatic and musculoskeletal diseases..

A Brave New World: Lessons from the COVID-19 Pandemic for Transitioning to Sustainable Supply and Production. (2020)
Journal Article
(2020). A Brave New World: Lessons from the COVID-19 Pandemic for Transitioning to Sustainable Supply and Production. Resources, Conservation and Recycling, https://doi.org/10.1016/j.resconrec.2020.104894

As members of the Future Earth Knowledge-Action Network on Systems of Sustainable Consumption and Production we have – as virtually everyone else – paid close attention to the COVID-19 pandemic which is one of the most comprehensive and tragic public... Read More about A Brave New World: Lessons from the COVID-19 Pandemic for Transitioning to Sustainable Supply and Production..