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All Outputs (1794)

Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies (2021)
Journal Article
Unsworth-White, S. R., Kitchen, M. O., & Bryan, R. T. (2022). Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies. Future Oncology, 18(1), 105-115. https://doi.org/10.2217/fon-2021-0781

Supplies of intravesical Bacillus Calmette-Guérin (BCG), the first-line treatment for most intermediate- and high-risk non-muscle-invasive bladder cancers (NMIBC), have proven unreliable over the past decade. This review considers the evolution of BC... Read More about Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies.

Impact of sex on outcomes of percutaneous coronary intervention for chronic total occlusion: A meta-analysis. (2021)
Journal Article
Mamas, M., Latif, A., Ahsan, M. J., Lateef, N., Aurit, S., Mirza, M. M., …Velagapudi, P. (2022). Impact of sex on outcomes of percutaneous coronary intervention for chronic total occlusion: A meta-analysis. Catheterization and Cardiovascular Interventions, 99(2), 254-262. https://doi.org/10.1002/ccd.30017

AbstractBackgroundWomen are underrepresented in chronic total occlusion (CTO) trials and little is known about sex differences in the outcomes of CTO percutaneous coronary intervention (PCI). This meta‐analysis aims to compare the outcomes of CTO PCI... Read More about Impact of sex on outcomes of percutaneous coronary intervention for chronic total occlusion: A meta-analysis..

Late Ediacaran occurrences of the organic-walled microfossils Granomarginata and flask-shaped Lagoenaforma collaris gen. et sp. nov. (2021)
Journal Article
(2021). Late Ediacaran occurrences of the organic-walled microfossils Granomarginata and flask-shaped Lagoenaforma collaris gen. et sp. nov. Geological Magazine, 1 - 22. https://doi.org/10.1017/s0016756821001096

Abstract New occurrences of flask-shaped and envelope-bearing microfossils, including the predominantly Cambrian taxon Granomarginata, are reported from new localities, as well as from earlier in time (Ediacaran) than previously known. The stratigrap... Read More about Late Ediacaran occurrences of the organic-walled microfossils Granomarginata and flask-shaped Lagoenaforma collaris gen. et sp. nov..

Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier (2021)
Journal Article
(2021). Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier. Contributions to Mineralogy and Petrology, https://doi.org/10.1007/s00410-021-01854-w

The major-element chemical composition of garnet provides valuable petrogenetic information, particularly in metamorphic rocks. When facing detrital garnet, information about the bulk-rock composition and mineral paragenesis of the initial garnet-bea... Read More about Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier.

ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL (2021)
Journal Article
Lucas de Oliveira, F. C., Williamson, S., Ardern, C. L., Heron, N., Christa Janse van Rensburg, D., Jansen, M. G., …Pluim, B. M. (2021). ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL. Sports Medicine and Health Science, https://doi.org/10.1016/j.smhs.2021.11.001

Altered biomechanics due to amputation can contribute to substantial limitations, influencing sporting activities. Individuals with lower extremity amputations or congenital lower limb deficiency are encouraged to participate in para-sports. However,... Read More about ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL.

Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates (2021)
Journal Article
Reynisson, J., Wieczorek-Błauż, A., Kowalczyk, K., Błauż, A., Makal, A., Pawlędzio, S., …Plażuk, D. (2021). Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates. Dalton Transactions, 51(2), 491-508. https://doi.org/10.1039/d1dt03553c

The incorporation of the ferrocenyl moiety into a bioactive molecule may significantly alter the activity of the resulting conjugate. By applying this strategy, we designed ferrocenyl analogs of monastrol - the first low molecular weight kinesin spin... Read More about Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates.

Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier (2021)
Journal Article
(2021). Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier. Contributions to Mineralogy and Petrology, https://doi.org/10.1007/s00410-021-01854-w

The major-element chemical composition of garnet provides valuable petrogenetic information, particularly in metamorphic rocks. When facing detrital garnet, information about the bulk-rock composition and mineral paragenesis of the initial garnet-bea... Read More about Garnet major-element composition as an indicator of host-rock type: a machine learning approach using the random forest classifier.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Dual pathway inhibition in atherothrombosis prevention: yes, now we can! (2021)
Journal Article
SUMMARIA, F., BIONDI-ZOCCAI, G., ROMAGNOLI, E., MAMAS, M. A., FRANCHI, F., SEVERINO, P., …BHATT, D. L. (2023). Dual pathway inhibition in atherothrombosis prevention: yes, now we can!. Minerva Cardiology and Angiology, 71(4), 363-373. https://doi.org/10.23736/S2724-5683.21.05867-1

Despite ongoing developments, prevention and treatment of atherothrombotic cardiovascular disease remains a common challenge. Antithrombotic options for cardiocerebrovascular disease prevention involves a choice between dual antiplatelet therapy (DAP... Read More about Dual pathway inhibition in atherothrombosis prevention: yes, now we can!.

Chemical synthesis of 4'-thio and 4'-sulfinyl pyrimidine nucleoside analogues. (2021)
Journal Article
Guinan, M., Huang, N., Hawes, C. S., Lima, M. A., Smith, M., & Miller, G. J. (2021). Chemical synthesis of 4'-thio and 4'-sulfinyl pyrimidine nucleoside analogues. Organic and Biomolecular Chemistry, 20(7), 1401-1406. https://doi.org/10.1039/d1ob02097h

Analogues of the canonical nucleosides required for nucleic acid synthesis have a longstanding presence and proven capability within antiviral and anticancer research. 4'-Thionucleosides, that incorporate bioisosteric replacement of furanose oxygen w... Read More about Chemical synthesis of 4'-thio and 4'-sulfinyl pyrimidine nucleoside analogues..

Virtual Parts Repository 2: Model-Driven Design of Genetic Regulatory Circuits (2021)
Journal Article
Yang, B., James, K., Wipat, A., & Misirli, G. (2021). Virtual Parts Repository 2: Model-Driven Design of Genetic Regulatory Circuits. ACS synthetic biology, 3304-3315. https://doi.org/10.1021/acssynbio.1c00157

Engineering genetic regulatory circuits is key to the creation of biological applications that are responsive to environmental changes. Computational models can assist in understanding especially large and complex circuits for which manual analysis i... Read More about Virtual Parts Repository 2: Model-Driven Design of Genetic Regulatory Circuits.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mallen, Mason, Frisher, Mamas, Jordan, Marshall, …White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

An overview of the Paleocene-Eocene calcareous nannofossil biostratigraphy and bioevents in Egypt (2021)
Book Chapter
Faris, M., Farouk, S., & Shabaan, M. (2021). An overview of the Paleocene-Eocene calcareous nannofossil biostratigraphy and bioevents in Egypt. In M. Montenari (Ed.), Stratigraphy & Timescales (225-292). Elsevier. https://doi.org/10.1016/bs.sats.2021.09.003

Nineteen Paleocene-Eocene calcareous nannofossil bioevents are used to identify the zones from NP1 to NP20. Several events and climatic changes are reported across the Danian/Selandian, the Selandian/Thanetian, the Paleocene-Eocene, Early Eocene/Midd... Read More about An overview of the Paleocene-Eocene calcareous nannofossil biostratigraphy and bioevents in Egypt.

The ‘curious effects’ of acting: homosexuality, theatre and female impersonation at the University of Cambridge, 1900-1939 (2021)
Journal Article
Janes. (2022). The ‘curious effects’ of acting: homosexuality, theatre and female impersonation at the University of Cambridge, 1900-1939. Twentieth Century British History, 33(2), https://doi.org/10.1093/tcbh/hwab036

The University of Cambridge educated a significant proportion of Britain’s elite in the early twentieth century. The homosocial environment of the colleges was similar in many ways to that of the single-sex public boarding schools which many of the u... Read More about The ‘curious effects’ of acting: homosexuality, theatre and female impersonation at the University of Cambridge, 1900-1939.