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Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results (2022)
Journal Article
Bundred, N., Porta, N., Brunt, A. M., Cramer, A., Hanby, A., Shaaban, A. M., …Bliss, J. M. (2022). Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results. Clinical Cancer Research, 28(7), 1323 - 1334. https://doi.org/10.1158/1078-0432.CCR-21-3177

PURPOSE: EPHOS-B aimed to determine whether perioperative anti-HER2 therapy inhibited proliferation and/or increased apoptosis in HER2-positive breast cancer. PATIENTS AND METHODS: This randomized phase II, two-part, multicenter trial included newly... Read More about Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results.

Blockchain Technology in the Fashion Industry (2022)
Journal Article
Singh, H., Jain, G., Kumar, N., & Hashimy, L. (2022). Blockchain Technology in the Fashion Industry. Journal of Electronic Commerce in Organizations, 1 - 21

<p>The concept of fashion has been coupled with technology, where technology has become the protagonist. The transparency between an organization and a customer works as a catalyst, and the customer has taken a more mainstream role. With blockchain t... Read More about Blockchain Technology in the Fashion Industry.

George Perry (1771–1823): architect and naturalist (2022)
Journal Article
Leach, S., & Torrens, H. S. (2022). George Perry (1771–1823): architect and naturalist. Archives of Natural History, 49(1), 117-129. https://doi.org/10.3366/anh.2022.0762

George Perry (1771-1823) was an artist, architect and sculptor, with a deep interest in natural history and malacology. (His father, George Perry (c.1718-1771), was a pioneering industrialist, with a particular interest in geology and also the histor... Read More about George Perry (1771–1823): architect and naturalist.

George Perry (c.1718-1771): industrialist, cartographer and naturalist (2022)
Journal Article
(2022). George Perry (c.1718-1771): industrialist, cartographer and naturalist. Archives of Natural History, 102 - 116. https://doi.org/10.3366/anh.2022.0761

George Perry (c.1718–1771) is known for his involvement in the development of the iron and engineering industries of Coalbrookdale, Ironbridge Gorge, Shropshire and Liverpool, and also for his ambition to publish a history together with new maps of L... Read More about George Perry (c.1718-1771): industrialist, cartographer and naturalist.

Intra-sphincteric botulinum toxin in the management of functional biliary pain (2022)
Journal Article
(2022). Intra-sphincteric botulinum toxin in the management of functional biliary pain. Endoscopy International Open, E521 - E527. https://doi.org/10.1055/a-1784-0061

<jats:title>Abstract</jats:title><jats:p> Background and study aims The management of functional biliary-type pain remains a clinical challenge. Intra sphincteric botulinum toxin putatively exerts an anti-spasmodic and anti-nociceptive effect. The ob... Read More about Intra-sphincteric botulinum toxin in the management of functional biliary pain.

The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review. (2022)
Journal Article
Kwok, C. S., Muntean, E., & Mallen, C. D. (2022). The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review. Journal of Medical Virology, 94(8), 3634-3641. https://doi.org/10.1002/jmv.27758

The spread of COVID-19 infection has changed the world. Population-based studies of COVID-19 are limited because it is unknown why events happen or why certain outcomes occur. An alternative approach called the patient pathway review evaluates what h... Read More about The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review..

Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus (2022)
Journal Article
Collings, A. (2022). Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus. Frontiers in Bioengineering and Biotechnology, https://doi.org/10.3389/fbioe.2022.806174

<jats:p>Using their abundant musculature, frogs are able to exhibit outstanding behavioural versatility. However, understanding the dynamic motion of their 30 + hindlimb muscles, with multi-joint action, and curved pathways, is challenging. This is p... Read More about Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus.

Clinical and angiographic success and safety comparison of coronary intravascular lithotripsy: An updated meta-analysis (2022)
Journal Article
Mamas, M. (2022). Clinical and angiographic success and safety comparison of coronary intravascular lithotripsy: An updated meta-analysis. https://doi.org/10.1016/j.ijcha.2022.100975

Background
Intravascular lithotripsy (IVL) can be used to assist stent deployment in severe coronary artery calcifications (CAC).

Methods
Studies employing IVL for CAC lesions were included. The primary outcomes included clinical and angiographi... Read More about Clinical and angiographic success and safety comparison of coronary intravascular lithotripsy: An updated meta-analysis.

Anxiety predicts impulsive-compulsive behaviours in Parkinson’s Disease: clinical relevance and theoretical implications (2022)
Journal Article
Di Rosa, E., Mapelli, D., Ronconi, L., Macchia, E., Gentili, C., Bisiacchi, P., & Edelstyn, N. (2022). Anxiety predicts impulsive-compulsive behaviours in Parkinson’s Disease: clinical relevance and theoretical implications. Journal of Psychiatric Research, 220-229. https://doi.org/10.1016/j.jpsychires.2022.01.052

Patients with Parkinson’s Disease (PD) often present symptoms of anxiety, depression and apathy. These negative affect manifestations have been recently associated with the presence of Impulsive-Compulsive Behaviours (ICBs). However, their relation w... Read More about Anxiety predicts impulsive-compulsive behaviours in Parkinson’s Disease: clinical relevance and theoretical implications.

An evaluation of a pilot multi-professional offender personality disorder (OPD) higher education programme (2022)
Journal Article
Lamph, G., Elliott, A., Gardner, K., Wright, K., Jones, E., Haslam, M., …McKeown, M. (2022). An evaluation of a pilot multi-professional offender personality disorder (OPD) higher education programme. Journal of Forensic Practice, 24(2), 138-155. https://doi.org/10.1108/JFP-10-2021-0051

Purpose
Workforce development is crucial to the offender personality disorder (OPD) service to provide contemporary, evidenced care and treatment. This study aims to provide an overview and the research evaluation results of a regional higher educat... Read More about An evaluation of a pilot multi-professional offender personality disorder (OPD) higher education programme.

Moth declines are most severe in broadleaf woodlands despite a net gain in habitat availability - data and code for analysis (2022)
Dataset
Blumgart, D., Botham, M., Menéndez, R., & Bell, J. (2022). Moth declines are most severe in broadleaf woodlands despite a net gain in habitat availability - data and code for analysis. [Dataset]. https://doi.org/10.23637/rothamsted.98852

This collection of datasets and R code contains all that is necessary to repeat the analysis in the publication "Moth declines are most severe in broadleaf woodlands despite a net gain in habitat availability" - Blumgart et al. 2022. It contains moth... Read More about Moth declines are most severe in broadleaf woodlands despite a net gain in habitat availability - data and code for analysis.

The Equality, Diversity and Inclusion Engagement Fellowship Pilot AHRC Funding Scheme Report 2020 - 2022 (2022)
Report
Blackburn, M., Coutinho, K. S. M., & Suviste, H. (2022). The Equality, Diversity and Inclusion Engagement Fellowship Pilot AHRC Funding Scheme Report 2020 - 2022. AHRC (Arts & Humanities Research Council)

This report provides an assessment and commentary on the AHRC’s 2020—22 Equality, Diversity and Inclusion Engagement Fellowship (EDIEF) pilot observing the successes, challenges, and benefits of its existence during its first iteration. The report ai... Read More about The Equality, Diversity and Inclusion Engagement Fellowship Pilot AHRC Funding Scheme Report 2020 - 2022.

Improving the Cybersecurity of Critical National Infrastructure using Modelling and Simulation (2022)
Report
D Ani, U., D McK Watson, J., Tuptuk, N., Hailes, S., Carr, M., & Maple, C. (2022). Improving the Cybersecurity of Critical National Infrastructure using Modelling and Simulation. PETRAS

The UK Critical National Infrastructure is critically dependent on digital technologies that provide communications, monitoring, control, and decision-support functionalities. Digital technologies are progressively enhancing efficiency, reliability,... Read More about Improving the Cybersecurity of Critical National Infrastructure using Modelling and Simulation.

Management and outcomes of acute myocardial infarction in patients with preexisting heart failure: an analysis of 2 million patients from the national inpatient sample. (2022)
Journal Article
Mamas. (2022). Management and outcomes of acute myocardial infarction in patients with preexisting heart failure: an analysis of 2 million patients from the national inpatient sample. Expert Review of Cardiovascular Therapy, 233 - 240. https://doi.org/10.1080/14779072.2022.2058931

BACKGROUND: Inpatient management and outcomes of patients presenting with acute myocardial infarction (AMI) with a history of heart failure (HF) have not been well characterized. METHODS: Hospitalizations for AMI from the Nationwide Inpatient Sample... Read More about Management and outcomes of acute myocardial infarction in patients with preexisting heart failure: an analysis of 2 million patients from the national inpatient sample..

A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT (2022)
Journal Article
Littlewood, E., Chew-Graham, C. A., Coleman, E., Gascoyne, S., Sloan, C., Ali, S., …Ekers, D. (2022). A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT. Public Health Research, 10(5), 1-160. https://doi.org/10.3310/ekze0617

Background Depression is common in people with long-term health conditions, and this combination can lead to worsened health outcomes and increased health-care costs. Subthreshold depression, a risk factor for major depression, is prevalent in this p... Read More about A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT.