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Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study (2024)
Journal Article
Cole, A., Weight, N., Mishra, S., Grapsa, J., Rutter, M. K., Siudak, Z., …Mamas, M. A. (in press). Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. Diabetologia, https://doi.org/10.1007/s00125-024-06281-7

Aims/hypothesis
The aim of this study was to investigate how diabetes mellitus affects longer term outcomes in individuals presenting to hospital with non-ST segment elevation myocardial infarction (NSTEMI).

Methods
We analysed data from 456,376... Read More about Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study.

The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study (2024)
Journal Article
Weight, N., Moledina, S., Lawson, C. A., Van Spall, H. G. C., Wijeysundera, H. C., Rashid, M., …Mamas, M. A. (in press). The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study. Angiology, https://doi.org/10.1177/00033197241273433

Patients with lower socioeconomic status (SES) have poorer outcomes following acute myocardial infarction (AMI) than patients with higher SES; however, how sex modifies socioeconomic differences is unclear. Using the United Kingdom (UK) Myocardial Is... Read More about The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study.

Short‐term risk of cardiovascular events in people newly diagnosed with gout (2024)
Journal Article
Cipolletta, E., Nakafero, G., Richette, P., Avery, A. J., Mamas, M. A., Tata, L. J., & Abhishek, A. (in press). Short‐term risk of cardiovascular events in people newly diagnosed with gout. Arthritis & Rheumatology, https://doi.org/10.1002/art.42986

ObjectivesTo investigate the temporal association between first diagnosis of gout and cardiovascular events in the short‐term.MethodsWe performed a self‐controlled case series analysis and a cohort study using data from linked primary care, hospitali... Read More about Short‐term risk of cardiovascular events in people newly diagnosed with gout.

Global burden of cardiovascular diseases: projections from 2025 to 2050 (2024)
Journal Article
Chong, B., Jayabaskaran, J., Jauhari, S. M., Chan, S. P., Goh, R., Kueh, M. T. W., …Chan, M. Y. (in press). Global burden of cardiovascular diseases: projections from 2025 to 2050. European Journal of Preventive Cardiology, https://doi.org/10.1093/eurjpc/zwae281

Aims
The prediction of future trends in cardiovascular disease (CVD) mortality and their risk factors can assist policy-makers in healthcare planning. This study aims to project geospatial trends in CVDs and their underlying risk factors from 2025 t... Read More about Global burden of cardiovascular diseases: projections from 2025 to 2050.

In‐hospital outcomes of ad hoc versus planned PCI for unprotected left‐main disease: An analysis of 8574 cases from British Cardiovascular Intervention Society database 2006–2018 (2024)
Journal Article
Kinnaird, T., Gallagher, S., Farooq, V., Protty, M. B., Cranch, H., Devlin, P., …Mamas, M. A. (in press). In‐hospital outcomes of ad hoc versus planned PCI for unprotected left‐main disease: An analysis of 8574 cases from British Cardiovascular Intervention Society database 2006–2018. Catheterization and Cardiovascular Interventions, https://doi.org/10.1002/ccd.31210

Background: Although data suggests ad hoc percutaneous coronary intervention (PCI) results in similar patient outcomes compared to planned PCI in nonselected patients, data for ad hoc unprotected left main stem PCI (uLMS‐PCI) are lacking. Aim: To det... Read More about In‐hospital outcomes of ad hoc versus planned PCI for unprotected left‐main disease: An analysis of 8574 cases from British Cardiovascular Intervention Society database 2006–2018.

Safety, efficacy, and optical coherence tomography insights into intravascular lithotripsy for the modification of non‐eruptive calcified nodules: A prospective observational study (2024)
Journal Article
Gupta, A., Shrivastava, A., Chhikara, S., Revaiah, P. C., Mamas, M. A., Vijayvergiya, R., …Mahesh, N. K. (in press). Safety, efficacy, and optical coherence tomography insights into intravascular lithotripsy for the modification of non‐eruptive calcified nodules: A prospective observational study. Catheterization and Cardiovascular Interventions, 104(4), 688-696. https://doi.org/10.1002/ccd.31217

Background
Non-eruptive calcium nodules (CNs) are commonly seen in heavily calcified coronary artery disease. They are the most difficult subset for modification, and may result in stent damage, malapposition and under-expansion. There are only limi... Read More about Safety, efficacy, and optical coherence tomography insights into intravascular lithotripsy for the modification of non‐eruptive calcified nodules: A prospective observational study.

Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020) (2024)
Journal Article
Chobufo, M., Ali, S., Taha, A., Duhan, S., Patel, N., Gonuguntla, K., …Balla, S. (2024). Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020). Birth Defects Research, 116(9), 1-8. https://doi.org/10.1002/bdr2.2398

Background
Infant mortality continues to be a significant problem for patients with congenital heart disease (CHD). Limited data exist on the recent trends of mortality in infants with CHD.

Methods
The CDC WONDER (Centers for Disease Control and... Read More about Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020).

Comparative analysis of cardiogenic shock outcomes in acute myocardial infarction with polyvascular disease (2024)
Journal Article
Gatuz, M. V., Abu-Fanne, R., Abramov, D., Barel, M., Mamas, M. A., Roguin, A., & Kobo, O. (2024). Comparative analysis of cardiogenic shock outcomes in acute myocardial infarction with polyvascular disease. American Heart Journal Plus: Cardiology Research and Practice, 46, Article 100452. https://doi.org/10.1016/j.ahjo.2024.100452

Background
Cardiogenic shock (CS) is the leading cause of mortality in acute myocardial infarction (AMI) patients, especially in those with vascular disease. This study aimed to assess the association between extent of polyvascular disease and the i... Read More about Comparative analysis of cardiogenic shock outcomes in acute myocardial infarction with polyvascular disease.

Diabetes and Its Impact on Cardiogenic Shock Outcomes in Acute Myocardial Infarction with Polyvascular Disease: A Comparative Analysis (2024)
Journal Article
Gatuz, M. V., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (in press). Diabetes and Its Impact on Cardiogenic Shock Outcomes in Acute Myocardial Infarction with Polyvascular Disease: A Comparative Analysis. Biomedicines, 12(8), Article 1900. https://doi.org/10.3390/biomedicines12081900

Background: Diabetes mellitus (DM) significantly impacts cardiovascular outcomes, particularly in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). The presence of polyvascular disease further complicates the prog... Read More about Diabetes and Its Impact on Cardiogenic Shock Outcomes in Acute Myocardial Infarction with Polyvascular Disease: A Comparative Analysis.

Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up. (2024)
Journal Article
Weight, N., Moledina, S., Ullah, M., Wijeysundera, H. C., Davies, S., Chew, N. W. S., …Mamas, M. A. (in press). Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up. Journal of the American Heart Association, 13(16), Article e032671. https://doi.org/10.1161/JAHA.123.032671

A growing population of patients with chronic kidney disease (CKD) presents with non-ST-segment-elevation myocardial infarction, although little is known about their longer-term mortality. Using the MINAP (Myocardial Ischaemia National Audit Project)... Read More about Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up..

2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients (2024)
Journal Article
Sokhal, B., Matetić, A., Protheroe, J., Helliwell, T., Myint, P., Paul, T., …Mamas, M. (2024). 2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients. Age and ageing, 53(Supplement_3), https://doi.org/10.1093/ageing/afae139.051

Introduction Data are limited on whether the causes of Emergency Department (ED) attendance and clinical outcomes vary by frailty status. Methods Using data from the Nationwide Emergency Department Sample, all ED attendances from 2016 to 2018 were st... Read More about 2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients.

EXPRESS: Dual Versus Triple Antithrombotic Therapy in Atrial Fibrillation and Acute Coronary Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials. (2024)
Journal Article
Sainbayar, E., Pham, H. N., Olson, A., Ibrahim, R., Grewal, H., Salih, M., …Mamas, M. A. (in press). EXPRESS: Dual Versus Triple Antithrombotic Therapy in Atrial Fibrillation and Acute Coronary Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials. Journal of Investigative Medicine, https://doi.org/10.1177/10815589241270640

Antithrombotic treatment in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) poses a dilemma. We compared outcomes of dual thrombotic therapy (DAT) (direct oral anticoagulants [DOACs]/warfarin + antiplatelets) versus triple an... Read More about EXPRESS: Dual Versus Triple Antithrombotic Therapy in Atrial Fibrillation and Acute Coronary Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials..

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..

30-Day unplanned readmission rates, causes and outcomes of patients hospitalized for acute coronary syndrome based on the trial participation status. (2024)
Journal Article
Matetic, A., Kuchtaruk, A., Siudak, Z., Ullah, W., Elbadawi, A., Elgendy, I. Y., …Mamas, M. A. (in press). 30-Day unplanned readmission rates, causes and outcomes of patients hospitalized for acute coronary syndrome based on the trial participation status. Cardiovascular Revascularization Medicine, https://doi.org/10.1016/j.carrev.2024.07.023

This study aimed to investigate the association between index trial participation status and 30-day unplanned readmission rates, causes, and outcomes in acute coronary syndrome (ACS) patients. The National Readmission Database was analysed for all in... Read More about 30-Day unplanned readmission rates, causes and outcomes of patients hospitalized for acute coronary syndrome based on the trial participation status..

Wait-times Benchmarks for risk-based prioritization in Transcatheter Aortic Valve Implantation: a simulation study. (2024)
Journal Article
Miranda, R. N., Austin, P. C., Fremes, S. E., Mamas, M. A., Sud, M. K., Naimark, D. M. J., & Wijeysundera, H. C. (in press). Wait-times Benchmarks for risk-based prioritization in Transcatheter Aortic Valve Implantation: a simulation study. European Heart Journal - Quality of Care and Clinical Outcomes, 1-9. https://doi.org/10.1093/ehjqcco/qcae059

Demand for transcatheter aortic valve implantation (TAVI) has increased in the last decade, resulting in prolonged wait-times and undesirable health outcomes in many health systems. Risk-based prioritization and wait-times benchmarks can improve equi... Read More about Wait-times Benchmarks for risk-based prioritization in Transcatheter Aortic Valve Implantation: a simulation study..

Bleeding risk prediction after acute myocardial infarction-integrating cancer data: the updated PRECISE-DAPT cancer score (2024)
Journal Article
Dafaalla, M., Costa, F., Kontopantelis, E., Araya, M., Kinnaird, T., Micari, A., …Mamas, M. A. (in press). Bleeding risk prediction after acute myocardial infarction-integrating cancer data: the updated PRECISE-DAPT cancer score. European Heart Journal, Article ehae463. https://doi.org/10.1093/eurheartj/ehae463

Background and Aims
This study assessed the impact of incorporating cancer as a predictor on performance of the PRECISE-DAPT score.

Methods
A nationally linked cohort of ST-elevation myocardial infarction patients between 1 January 2005 and 31 M... Read More about Bleeding risk prediction after acute myocardial infarction-integrating cancer data: the updated PRECISE-DAPT cancer score.

The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions (2024)
Journal Article
Goh, R. S. J., Chong, B., Jayabaskaran, J., Jauhari, S. M., Chan, S. P., Kueh, M. T. W., …Chew, N. W. (2024). The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions. The Lancet Regional Health - Western Pacific, 49, Article 101138. https://doi.org/10.1016/j.lanwpc.2024.101138

Background
Given the rapidly growing burden of cardiovascular disease (CVD) in Asia, this study forecasts the CVD burden and associated risk factors in Asia from 2025 to 2050.

M... Read More about The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions.

Impact of historical Partitions of Poland on reperfusion delay in patients with ST-elevation myocardial infarction referred to primary percutaneous coronary intervention (from the ORPKI Registry) (2024)
Journal Article
Dziewierz, A., Rakowski, T., Mamas, M. A., Tkaczyk, F., Sowa, Ł., Malinowski, K. P., …Siudak, Z. (in press). Impact of historical Partitions of Poland on reperfusion delay in patients with ST-elevation myocardial infarction referred to primary percutaneous coronary intervention (from the ORPKI Registry). Polish Archives of Internal Medicine, 134(7-8), 1-4. https://doi.org/10.20452/pamw.16793

The time from symptom onset to reperfusion critically influences outcomes in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).1,2 Notably, treatment times serve as a benchmark... Read More about Impact of historical Partitions of Poland on reperfusion delay in patients with ST-elevation myocardial infarction referred to primary percutaneous coronary intervention (from the ORPKI Registry).