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Outputs (30)

The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope (2024)
Journal Article
Mercer, L., Abhishek, A., Kavirayani, A., Ahmed, A., Davidson, A., Foulkes, A., …Galloway, J. (in press). The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(3), Article rkae077. https://doi.org/10.1093/rap/rkae077

Lay Summary: What does this mean for patients? A revised guideline, produced by the British Society for Rheumatology (BSR), will provide up-to-date information about the safe prescribing and monitoring of the effects of non-biologic (or conventional... Read More about The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope.

Coproducing Health Information Materials With Young People: Reflections and Lessons Learned (2024)
Journal Article
Faux-Nightingale, A., Somayajula, G., Bradbury, C., Bray, L., Burton, C., Chew-Graham, C. A., …Welsh, V. (2024). Coproducing Health Information Materials With Young People: Reflections and Lessons Learned. Health Expectations, 27(3), Article e14115. https://doi.org/10.1111/hex.14115

Background This paper describes and critically reflects on how children and young people (CYP) acted as public advisors to co-produce health information materials about Long Covid for younger audiences. This work was underpinned by the Lundy model,... Read More about Coproducing Health Information Materials With Young People: Reflections and Lessons Learned.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., …Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope (2024)
Journal Article
Toyoda, T., Armitstead, Z., Bhide, S., Engamba, S., Henderson, E., Jones, C., …Yates, M. (in press). Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(1), Article rkae002. https://doi.org/10.1093/rap/rkae002

The last British Society for Rheumatology (BSR) guideline on PMR was published in 2009. The guideline needs to be updated to provide a summary of the current evidence for pharmacological and non-pharmacological management of adults with PMR. This gui... Read More about Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope.

A Scoping Review of the Effects of Ambient Air Quality on Cognitive Frailty (2023)
Journal Article
Hodgson, J. R., Benkowitz, C., Castellani, B. C., Ellison, A., Yassaie, R., Twohig, H., …Fowler-Davis, S. (2023). A Scoping Review of the Effects of Ambient Air Quality on Cognitive Frailty. Environments, 11(1), Article 4. https://doi.org/10.3390/environments11010004

Environmental and public health research has given considerable attention to the impact of air quality on brain health, with systematic reviews being widespread. No literature review has been conducted for cognitive frailty—a multidimensional syndrom... Read More about A Scoping Review of the Effects of Ambient Air Quality on Cognitive Frailty.

Experiences and care needs of children with long Covid: a qualitative study. (2023)
Journal Article
Faux-Nightingale, A., Saunders, B., Burton, C., Chew-Graham, C. A., Somayajula, G., Twohig, H., & Welsh, V. (2023). Experiences and care needs of children with long Covid: a qualitative study. British Journal of General Practice Open (BJGP Open), 8(1), Article 0143. https://doi.org/10.3399/BJGPO.2023.0143

Long Covid, the patient-preferred term, describes symptoms persisting after an acute episode of Covid-19 infection. Symptoms in children and young people (CYP) can affect daily routine, with broader impacts on education, health-related quality of lif... Read More about Experiences and care needs of children with long Covid: a qualitative study..

Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink (2023)
Journal Article
Scott, I. C., Jordan, K. P., Twohig, H., Whittle, R., Muller, S., Hider, S. L., …Bailey, J. (2023). Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink. Rheumatology, Article kead463. https://doi.org/10.1093/rheumatology/kead463

Despite little evidence that analgesics are effective in inflammatory arthritis (IA), studies report substantial opioid prescribing. The extent this applies to other analgesics is uncertain. We undertook a comprehensive evaluation of analgesic prescr... Read More about Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

Applying the consolidated framework for implementation research to evaluate the community rapid intervention service (2023)
Journal Article
Moult, A., Baker, D., Twohig, H., Missen, M., Iqbal, Z., Duffy, H., & Paskins, Z. (2023). Applying the consolidated framework for implementation research to evaluate the community rapid intervention service. BMC Health Services Research, 23(1), 844. https://doi.org/10.1186/s12913-023-09864-z

Background: Developed in 2019, the Community Rapid Intervention Service (CRIS) is a community intervention service aiming to prevent hospital admissions. CRIS provides a response within two hours to patients with sub-acute medical needs in their usua... Read More about Applying the consolidated framework for implementation research to evaluate the community rapid intervention service.

Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study (2023)
Journal Article
Leung, J. L., Twohig, H., Muller, S., Maxwell, L., Mackie, S. L., Neill, L. M., & Owen, C. E. (2023). Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study. Seminars in Arthritis and Rheumatism, 62, 152239. https://doi.org/10.1016/j.semarthrit.2023.152239

Objective To examine the test-retest reliability of four measurement instruments in polymyalgia rheumatica (PMR): pain severity visual analogue scale (VAS) / numerical rating score (NRS), stiffness severity VAS/NR... Read More about Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study.

P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum (2023)
Presentation / Conference
C Scott, I., Whittle, R., Bailey, J., Twohig, H., L Hider, S., D Mallen, C., …P Jordan, K. (2023, April). P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Background/Aims Pain is a common symptom experienced by patients with inflammatory arthritis (IA). Emerging data indicate IA pain treatment focuses on prescribing analgesics despite an absence of evidence for long-term efficacy. Delivering optimal,... Read More about P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum.

Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article
Faux-Nightingale, A., Burton, C., Twohig, H., Bucknall, M., Carroll, W., Chew-Graham, C., …Welsh, V. (2023). Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. British Journal of General Practice Open (BJGP Open), 7(2), Article BJGPO20220149. https://doi.org/10.3399/bjgpo.2022.0149

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks. Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data. The Lancet Regional Health Europe, 23, Article 100519. https://doi.org/10.1016/j.lanepe.2022.100519

Background: Contemporary data on rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (SpA) epidemiology in England are lacking. This knowledge is crucial to planning healthcare services. We updated algorithms defining pat... Read More about Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data.

Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica. (2022)
Journal Article
Twohig, H., Mitchell, C., Mallen, C., & Muller, S. (2022). Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica. Rheumatology, https://doi.org/10.1093/rheumatology/keac317/6593480

OBJECTIVES: Polymyalgia rheumatica (PMR) causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient's perspective is vital to high-quality research and patient-centred care, yet there are no validate... Read More about Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica..

P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.182

Abstract Background/Aims The substantial personal and socioeconomic costs associated with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) make understanding their epidemiology crucial. The Clinical Practice Re... Read More about P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data.

Primary care for people with severe mental illness and comorbid obstructive airways disease: a qualitative study of patient perspectives with integrated stakeholder feedback (2022)
Journal Article
Mitchell, C., Zuraw, N., Delaney, B., Twohig, H., Dolan, N., Walton, E., …Hulin, J. (2022). Primary care for people with severe mental illness and comorbid obstructive airways disease: a qualitative study of patient perspectives with integrated stakeholder feedback. BMJ Open, 12(3), Article e057143. https://doi.org/10.1136/bmjopen-2021-057143

OBJECTIVES: To explore patient and stakeholder perspectives on primary respiratory care for people with severe mental illness (SMI) and comorbid obstructive airways disease (OAD). DESIGN: Qualitative, semistructured qualitative interviews were undert... Read More about Primary care for people with severe mental illness and comorbid obstructive airways disease: a qualitative study of patient perspectives with integrated stakeholder feedback.

Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. (2020)
Journal Article
Twohig, H., Owen, C., Muller, S., Mallen, C., Mitchell, C., Hider, S., …Hill, C. (2021). Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. Journal of Rheumatology, 48(6), 883-893. https://doi.org/10.3899/jrheum.200248

OBJECTIVE: To systematically identify the outcome measures and instruments used in clinical studies of polymyalgia rheumatica (PMR) and to evaluate evidence about their measurement properties. METHODS: Searches based on the MeSH term 'polymyalgia rhe... Read More about Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review..

Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study (2020)
Journal Article
Yates, M., Owen, C. E., Muller, S., Graham, K., Neill, L., Twohig, H., …Working Group, O. P. (2020). Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study. Journal of Rheumatology, 47(9), 1379-1384. https://doi.org/10.3899/jrheum.190575

OBJECTIVE: The aim of this study was to survey participants with PMR to evaluate the face validity, acceptability and domain match of proposed candidate outcome measures. METHODS: A structured, online, anonymous survey was disseminated by patient sup... Read More about Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study.

Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group. (2019)
Journal Article
Yates, M., Twohig, H., Muller, S., Neill, L., Harrison, E., Shea, B., …Mackie, S. (2019). Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group. Journal of Rheumatology, 46(10), 1360 - 1364. https://doi.org/10.3899/jrheum.181050

OBJECTIVE: To report the progress of the Outcome Measures in Rheumatology (OMERACT) Polymyalgia Rheumatica (PMR) Working Group in selecting candidate instruments for a core outcome measurement set. METHODS: A systematic literature review identified o... Read More about Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group..

Response to diagnosis of pre-diabetes in socioeconomically deprived areas: a qualitative study (2019)
Journal Article
Twohig, H., Hodges, V., Hobbis, C., & Mitchell, C. (2019). Response to diagnosis of pre-diabetes in socioeconomically deprived areas: a qualitative study. British Journal of General Practice Open (BJGP Open), 3(3), https://doi.org/10.3399/bjgpopen19x101661

Background Diabetes prevention is a key priority for the NHS, with a particular focus on populations at highest risk. The NHS Diabetes Prevention Programme (NHS DPP) has been introduced, offering a course of dietary and lifestyle education to indivi... Read More about Response to diagnosis of pre-diabetes in socioeconomically deprived areas: a qualitative study.

RESULTS OF A PATIENT SURVEY ON FEASIBILITY AND FACE VALIDITY OF OUTCOME MEASURES FOR INTENDED USE IN FUTURE STUDIES ENROLLING PARTICIPANTS WITH POLYMYALGIA RHEUMATICA (2019)
Journal Article
Yates, M., Owen, C., Muller, S., Graham, K., Neill, L., Twohig, H., …Hill, C. (2019). RESULTS OF A PATIENT SURVEY ON FEASIBILITY AND FACE VALIDITY OF OUTCOME MEASURES FOR INTENDED USE IN FUTURE STUDIES ENROLLING PARTICIPANTS WITH POLYMYALGIA RHEUMATICA. Rheumatology, 58(S3), https://doi.org/10.1093/rheumatology/kez107.033

The OMERACT Core Domain Set for Outcome Measures for Clinical Trials in Polymyalgia Rheumatica (2017)
Journal Article
Mackie, S., Neill, L., Harrison, E., Black, R., Kermani, T., Simon, L., …Twohig, H. (2017). The OMERACT Core Domain Set for Outcome Measures for Clinical Trials in Polymyalgia Rheumatica. Journal of Rheumatology, 1515-1521. https://doi.org/10.3899/jrheum.161109

OBJECTIVE To inform development of a core domain set for outcome measures for clinical trials in polymyalgia rheumatica (PMR), we conducted patient consultations, a systematic review, a Delphi study, and 2 qualitative studies. METHODS Domains i... Read More about The OMERACT Core Domain Set for Outcome Measures for Clinical Trials in Polymyalgia Rheumatica.

Assessment of the face validity. feasibility and utility of a patient-completed questionnaire for polymyalgia rheumatica: a postal survey using the QQ-10 questionnaire (2017)
Journal Article
Twohig, H., Jones, G., Mackie, S., Mallen, C., & Mitchell, C. (2017). Assessment of the face validity. feasibility and utility of a patient-completed questionnaire for polymyalgia rheumatica: a postal survey using the QQ-10 questionnaire. Pilot and Feasibility Studies, https://doi.org/10.1186/s40814-017-0150-y

Background The development of a patient-reported outcome measure (PROM) for polymyalgia rheumatica (PMR), a condition that causes pain, stiffness and disability, is necessary as there is no current validated disease-specific measure. Initial literat... Read More about Assessment of the face validity. feasibility and utility of a patient-completed questionnaire for polymyalgia rheumatica: a postal survey using the QQ-10 questionnaire.

Chronic kidney disease in elderly people: disease or disease label? (2016)
Journal Article
Ellam, T., Twohig, H., & Khwaja, A. (2016). Chronic kidney disease in elderly people: disease or disease label?. BMJ, 352, Article h6559. https://doi.org/10.1136/bmj.h6559

Around half of people aged over 75 meet current diagnostic criteria for chronic kidney disease (CKD). However, labelling them all as diseased is controversial and may cause unnecessary anxiety.1 2 The classification system defining this epidemic of C... Read More about Chronic kidney disease in elderly people: disease or disease label?.

"I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). (2015)
Journal Article
Twohig, H., Mitchell, C., Mallen, C., Adebajo, A., & Mathers, N. (2015). "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). Patient Education and Counseling, 98(5), 645 - 650. https://doi.org/10.1016/j.pec.2014.12.013

OBJECTIVES: To explore patient experiences of living with, and receiving treatment for, PMR. METHODS: Semi-structured qualitative interviews, with 22 patients with PMR recruited from general practices in South Yorkshire. Thematic analysis using a con... Read More about "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR)..