Helen Twohig's Outputs (10)

Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review] (2024)
Journal Article
Raquel Nunes, A., Atherton, H., Dahlmann, F., Eccles, A., Geddes, O., Gregg, M., Jowett, S., Karaba, F., Nelson, L., Spencer, R., Twohig, H., & Dale, J. (2024). Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review]. NIHR Open Research, 1-11. https://doi.org/10.3310/nihropenres.13833.1

Introduction
The urgency to address climate change and reduce carbon emissions in healthcare, highlighted in the United Kingdom (UK) by the 'Delivering a 'Net Zero' National Health Service (NHS)' report, emphasises the need for healthcare organisati... Read More about Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review].

Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum (2024)
Journal Article
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S. L., Mallen, C. D., Jordan, K. P., & Muller, S. (2024). Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum. BMC Medicine, 22(1), 575. https://doi.org/10.1186/s12916-024-03774-5

Background: Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated with... Read More about Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum.

Optimising inhaled therapy for patients with asthma. (2024)
Journal Article
Bansal, A., Franklin, L., & Twohig, H. (in press). Optimising inhaled therapy for patients with asthma. BMJ, 386, 1-6. https://doi.org/10.1136/bmj-2024-080353

What you need to know
Sub-optimally controlled asthma is common, in part because of normalisation of symptoms, underuse of preventer therapy, overuse of reliever therapy, and poor inhaler technique. Ensuring patients are using the right inhaled medi... Read More about Optimising inhaled therapy for patients with asthma..

Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol (2024)
Journal Article
Karaba, F., Raquel Nunes, A., Geddes, O., O, G., Atherton, H., Dahlmann, F., F, D., Eccles, A., A, E., Gregg, M., M, G., Spencer, R., Twohig, H., H, T., & Dale, J. (2024). Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol. BMJ Open, 14(9), https://doi.org/10.1136/bmjopen-2024-087795

Introduction: There is growing recognition of the importance of primary care in addressing climate change. The World Organisation of Family Doctors has urged general practitioners worldwide to commit to tackling climate change and to serve as agents... Read More about Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol.

The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope (2024)
Journal Article
Mercer, L., Abhishek, A., Kavirayani, A., Ahmed, A., Davidson, A., Foulkes, A., Jones, C., Nash, C., Rose-Parfitt, E., Dhillon, E., Zabate, G., Twohig, H., De Vere, H., Scott, J., Reynolds, J., Holmes, J., Hartley, K., Warrier, K., Nowak, K., Parsons, K., …Galloway, J. (in press). The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(3), Article rkae077. https://doi.org/10.1093/rap/rkae077

Lay Summary: What does this mean for patients? A revised guideline, produced by the British Society for Rheumatology (BSR), will provide up-to-date information about the safe prescribing and monitoring of the effects of non-biologic (or conventional... Read More about The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope.

AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM (2024)
Presentation / Conference Contribution
Scott, I., Daud, N., Bailey, J., Twohig, H., Hider, S., Mallen, C., Jordan, K., & Muller, S. AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM. Presented at EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria, Vienna

Background: Recent observational studies suggest gabapentinoids associate with an increased risk of fractures. The potential for confounding inherent to non-randomised studies of interventions, however, alongside th... Read More about AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM.

Coproducing Health Information Materials With Young People: Reflections and Lessons Learned (2024)
Journal Article
Faux-Nightingale, A., Somayajula, G., Bradbury, C., Bray, L., Burton, C., Chew-Graham, C. A., Gardner, A., Griffin, A., Twohig, H., & Welsh, V. (2024). Coproducing Health Information Materials With Young People: Reflections and Lessons Learned. Health Expectations, 27(3), Article e14115. https://doi.org/10.1111/hex.14115

Background
This paper describes and critically reflects on how children and young people (CYP) acted as public advisors to co-produce health information materials about Long Covid for younger audiences. This work was underpinned by the Lundy model,... Read More about Coproducing Health Information Materials With Young People: Reflections and Lessons Learned.

44 Impact of the danish comorbidity index for acute myocardial infarction score on 30-day unplanned readmission rates and causes in hospitalised patients with acute coronary syndrome (2024)
Presentation / Conference Contribution
Sokhal, B. S., Matetić, A., Marshall, M., Twohig, H., Shepherd, T., Mallen, C., & Mamas, M. (2024, June). 44 Impact of the danish comorbidity index for acute myocardial infarction score on 30-day unplanned readmission rates and causes in hospitalised patients with acute coronary syndrome. Paper presented at British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024, Manchester

Introduction This study aimed to investigate the association of the DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with the 30-day unplanned readmission rates and causes and in acute coronary syndrome (ACS) patients.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., Somayajula, G., van-Der-Windt, D., Welsh, V., & Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background
Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope (2024)
Journal Article
Toyoda, T., Armitstead, Z., Bhide, S., Engamba, S., Henderson, E., Jones, C., MacKeith, P., Maddock, J., Reynolds, G., Scrafton, N., Subesinghe, M., Subesinghe, S., Twohig, H., Mackie, S. L., & Yates, M. (in press). Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(1), Article rkae002. https://doi.org/10.1093/rap/rkae002

The last British Society for Rheumatology (BSR) guideline on PMR was published in 2009. The guideline needs to be updated to provide a summary of the current evidence for pharmacological and non-pharmacological management of adults with PMR. This gui... Read More about Treatment of polymyalgia rheumatica: British Society for Rheumatology guideline scope.