Skip to main content

Research Repository

Advanced Search

Mamas Mamas' Outputs (897)

Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset). (2021)
Journal Article
Mamas, M. (2021). Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset). https://doi.org/10.1016/j.amjcard.2020.12.060

The temporal trends and preprocedural predictors of emergency coronary artery bypass graft surgery (ECABG) after elective percutaneous coronary intervention (PCI) in the contemporary era are largely unknown. From January 2003 to December 2014 electiv... Read More about Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset)..

Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure (2021)
Journal Article
Sparrow, R., Sanjoy, S., Choi, Y.-H., Elgendy, I. Y., Jneid, H., Villablanca, P. A., Holmes, D. R., Pershad, A., Alraies, C., Sposato, L. A., Mamas, M. A., & Bagur, R. (2021). Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure. Heart, 107(24), 1946-1955. https://doi.org/10.1136/heartjnl-2020-318650

OBJECTIVE: This manuscript aims to explore the impact of race/ethnicity and socioeconomic status on in-hospital complication rates after left atrial appendage closure (LAAC). METHODS: The US National Inpatient Sample was used to identify hospitalisat... Read More about Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure.

Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF. (2021)
Journal Article
Pedro Ferreira, J., Verdonschot, J., Wang, P., Pizard, A., Collier, T., Ahmed, F. Z., Brunner-La-Rocca, H.-P., Clark, A. L., Cosmi, F., Cuthbert, J., Díez, J., Edelmann, F., Girerd, N., González, A., Grojean, S., Hazebroek, M., Khan, J., Latini, R., Mamas, M. A., Mariottoni, B., …Zannad, F. (2021). Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF. JACC: Heart Failure, 268 - 277. https://doi.org/10.1016/j.jchf.2020.11.010

OBJECTIVES: This study sought to further understand the mechanisms underlying effect of spironolactone and assessed its impact on multiple plasma protein biomarkers and their respective underlying biologic pathways. BACKGROUND: In addition to their b... Read More about Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF..

Individual participant data meta-analysis for external validation, recalibration, and updating of a flexible parametric prognostic model. (2021)
Journal Article
Ensor, J., Snell, K. I. E., Debray, T. P. A., Lambert, P. C., Look, M. P., Mamas, M. A., Moons, K. G. M., & Riley, R. D. (2021). Individual participant data meta-analysis for external validation, recalibration, and updating of a flexible parametric prognostic model. Statistics in Medicine, 40(13), 3066-3084. https://doi.org/10.1002/sim.8959

Individual participant data (IPD) from multiple sources allows external validation of a prognostic model across multiple populations. Often this reveals poor calibration, potentially causing poor predictive performance in some populations. However, r... Read More about Individual participant data meta-analysis for external validation, recalibration, and updating of a flexible parametric prognostic model..

Revascularisation strategies in patients with significant left main coronary disease during the COVID-19 pandemic. (2021)
Journal Article
Rashid, M., Mamas, Mohamed, M. O., Curzen, N., de Belder, M., Goodwin, A. T., Spratt, J. C., Balacumaraswami, L., Deanfield, J., Martin, G. P., Shoaib, A., Gale, C. P., Kinnaird, T., & Mamas, M. A. (2021). Revascularisation strategies in patients with significant left main coronary disease during the COVID-19 pandemic. Catheterization & Cardiovascular Interventions, 98(7), 1252-1261. https://doi.org/10.1002/ccd.29663

BACKGROUND: There are limited data on the impact of the COVID-19 pandemic on left main (LM) coronary revascularisation activity, choice of revascularisation strategy, and post-procedural outcomes. METHODS: All patients with LM disease (=50% stenosis)... Read More about Revascularisation strategies in patients with significant left main coronary disease during the COVID-19 pandemic..

Sex Differences in Ischemic Stroke Outcomes in Patients With Pulmonary Hypertension. (2021)
Journal Article
Mamas. (2021). Sex Differences in Ischemic Stroke Outcomes in Patients With Pulmonary Hypertension. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, e019341 - ?. https://doi.org/10.1161/JAHA.120.019341

Background The association between systemic hypertension and cerebrovascular disease is well documented. However, the impact of pulmonary hypertension (PH) on acute ischemic stroke outcomes is unknown despite PH being recognized as a risk factor for... Read More about Sex Differences in Ischemic Stroke Outcomes in Patients With Pulmonary Hypertension..

Impact of pre-existent vascular and poly-vascular disease on acute myocardial infarction management and outcomes: An analysis of 2 million patients from the National Inpatient Sample. (2021)
Journal Article
Mamas. (2021). Impact of pre-existent vascular and poly-vascular disease on acute myocardial infarction management and outcomes: An analysis of 2 million patients from the National Inpatient Sample. https://doi.org/10.1016/j.ijcard.2020.11.051

BACKGROUND: Patients with pre-existing vascular disease are known to have worse outcomes after acute myocardial infarction (AMI). However, there is limited data for outcomes stratified by type and number of vascular territories involved. METHODS: Usi... Read More about Impact of pre-existent vascular and poly-vascular disease on acute myocardial infarction management and outcomes: An analysis of 2 million patients from the National Inpatient Sample..

ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study (2021)
Journal Article
Mamas, & Mallen. (2021). ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study. Rheumatology, https://doi.org/10.1093/rheumatology/keab234

OBJECTIVES: To examine the association between ß-blocker prescription and first primary-care consultation for knee osteoarthritis (OA), hip OA, knee pain and hip pain. METHODS: Data source: Clinical Practice Research Datalink. Participants aged =40?y... Read More about ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study.

Prognosis of Acute Ischaemic Stroke in Cancer Patients: A National Inpatient Sample Study (2021)
Journal Article
Mamas. (2021). Prognosis of Acute Ischaemic Stroke in Cancer Patients: A National Inpatient Sample Study. MedRxiv,

Background and Purpose Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis... Read More about Prognosis of Acute Ischaemic Stroke in Cancer Patients: A National Inpatient Sample Study.

Racial differences in management and outcomes of acute myocardial infarction during COVID19 pandemic (2021)
Journal Article
Rashid, & Mamas. (2021). Racial differences in management and outcomes of acute myocardial infarction during COVID19 pandemic. Heart, 734-740. https://doi.org/10.1136/heartjnl-2020-318356

Objective: There are concerns that health care and outcomes of BAME communities are disproportionately impacted by the COVID19 pandemic. We investigated admission rates, treatment and mortality of Black, Asian and Minority Ethnic (BAME) with acute my... Read More about Racial differences in management and outcomes of acute myocardial infarction during COVID19 pandemic.

Percutaneous coronary intervention in patients with cancer and readmissions within 90 days for acute myocardial infarction and bleeding in the USA. (2021)
Journal Article
Mamas. (2021). Percutaneous coronary intervention in patients with cancer and readmissions within 90 days for acute myocardial infarction and bleeding in the USA. https://doi.org/10.1093/eurheartj/ehaa1032

AIMS: The post-discharge outcomes of patients with cancer who undergo PCI are not well understood. This study evaluates the rates of readmissions within 90?days for acute myocardial infarction (AMI) and bleeding among patients with cancer who undergo... Read More about Percutaneous coronary intervention in patients with cancer and readmissions within 90 days for acute myocardial infarction and bleeding in the USA..

Efficacy and Safety of Ticagrelor Monotherapy in Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis (2021)
Journal Article
Gelbenegger, G., Schoergenhofer, C., Jilma, B., Gager, G. M., Dizdarevic, A. M., Mamas, M. A., Parapid, B., Velagapudi, P., & Siller‐Matula, J. M. (2021). Efficacy and Safety of Ticagrelor Monotherapy in Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis. Clinical Pharmacology and Therapeutics, 110(2), 424-431. https://doi.org/10.1002/cpt.2226

Dual antiplatelet therapy (DAPT) and subsequent P2Y12 inhibitor monotherapy, particularly ticagrelor, is an emerging treatment strategy in patients undergoing percutaneous coronary intervention (PCI). This meta-analysis was designed to investigate wh... Read More about Efficacy and Safety of Ticagrelor Monotherapy in Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis.

Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. (2021)
Journal Article
Mamas. (2021). Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. https://doi.org/10.1007/s11886-021-01453-y

PURPOSE OF REVIEW: This article reviews the evidence on optimal medical therapy (OMT) versus coronary revascularization in patients with stable ischemic heart disease (SIHD) and advanced chronic kidney disease (CKD). RECENT FINDINGS: A post hoc analy... Read More about Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease..

Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease (2021)
Journal Article
Paul, T. K., Mamas, M. A., Shanmugasundaram, M., Nagarajarao, H. S., Ojha, C. P., Jneid, H., Kumar, G., & White, C. J. (2021). Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. Current Cardiology Reports, 23(4), https://doi.org/10.1007/s11886-021-01453-y

Purpose of Review
This article reviews the evidence on optimal medical therapy (OMT) versus coronary revascularization in patients with stable ischemic heart disease (SIHD) and advanced chronic kidney disease (CKD).

Recent Findings
A post hoc an... Read More about Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease.

Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample (2021)
Journal Article
Ullah, W., Al-Khadra, Y., Mir, T., Darmoch, F., Pacha, H. M., Sattar, Y., Ijioma, N., Mohamed, M. O., Kwok, C. S., Asfour, A. I., Kapadia, S., Rizik, D., Zehr, K., Mamas, M. A., & Alraies, M. C. (2021). Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample. Journal of Cardiovascular Medicine, 22(7), 586 - 593. https://doi.org/10.2459/JCM.0000000000001172

AIM: We sought to determine the racial and ethnical disparities in the delivery of TAVR and to evaluate the in-hospital outcomes and utilization of TAVR stratified by patient ethnicity. METHOD: Using a national inpatient sample database between 2011... Read More about Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample.

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. MedRxiv, https://doi.org/10.1101/2021.02.14.21251130v1

<h4>Background</h4> People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opport... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.

Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (Nationwide Readmissions Database). (2021)
Journal Article
Mamas, Sykes, R., Mohamed, M. O., Kwok, C. S., Mamas, M. A., & Berry, C. (2021). Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (Nationwide Readmissions Database). Clinical Cardiology, 44(3), 291 - 306. https://doi.org/10.1002/clc.23543

Percutaneous coronary intervention (PCI) improves anginal chest pain in most, but not all, treated patients. PCI is associated with unplanned readmission for angina and non-specific chest pain within 30-days of index PCI. Patients with an index hospi... Read More about Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (Nationwide Readmissions Database)..