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Major Bleeding and Adverse Outcome following Percutaneous Coronary Intervention (2015)
Journal Article
Holroyd, E. W., Khoo, C. W., Butler, R., Fraser, D. G., Nolan, J., & Mamas, M. A. (2015). Major Bleeding and Adverse Outcome following Percutaneous Coronary Intervention. Interventional Cardiology: Reviews, Research, Resources, 10(1), 22-25. https://doi.org/10.15420/icr.2015.10.1.22

Advances in anti-thrombotic and anti-platelet therapies have improved outcomes in patients undergoing percutaneous coronary interventions (PCIs) through a reduction in ischaemic events, at the expense of peri-procedural bleeding complications. These... Read More about Major Bleeding and Adverse Outcome following Percutaneous Coronary Intervention.

Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom (2015)
Journal Article
Mamas. (2015). Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom. European Heart Journal, 1312-1320. https://doi.org/10.1093/eurheartj/ehv631

The HORIZONS trial reported a survival advantage for bivalirudin over heparin-with-glycoprotein inhibitors (GPIs) in primary PCI for ST elevation myocardial infarction. This drove an international shift in clinical practice. Subsequent studies have p... Read More about Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom.

Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study (2015)
Journal Article
Mamas. (2015). Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study. European Heart Journal: Acute Cardiovascular Care, 191-198. https://doi.org/10.1177/2048872615623038

Objective: This study aims to study the prognostic impact of LV function on mortality and examine the effect of age on the prognostic value of left ventricular function. Methods: We examined the Myocardial Ischaemia National Audit Project (MINAP) reg... Read More about Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study.

Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis (2015)
Journal Article
Mamas. (2015). Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis. Diabetes Care, 2354-2369. https://doi.org/10.2337/dc15-1188

OBJECTIVE Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular... Read More about Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis.

Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues (2015)
Journal Article
Mamas, M., & Nolan, J. (2015). Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues. JACC: Cardiovascular Interventions, 1405-1409. https://doi.org/10.1016/j.jcin.2015.06.016

In the recently published MATRIX (Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX) trial, the use of transradial access (TRA) compared to transfemoral access (TFA) during percutaneous coronary i... Read More about Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues.

Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database (2015)
Journal Article
Mamas. (2015). Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/CIRCINTERVENTIONS.117.005581

Background: The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients with a history of bypass surgery (PCI-CABG) is limited and the long-term effects unclear. Using a national PCI database, the i... Read More about Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database.

Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies (2015)
Journal Article
Nolan, Rashid, & Mamas. (2015). Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies. Cardiovascular Revascularization Medicine, 484-490. https://doi.org/10.1016/j.carrev.2015.08.008

Objectives The aim of this study is to review the available literature on the efficacy and safety of agents used for prevention of RAS. Background Different vasodilator agents have been used to prevent radial artery spasm (RAS) in patients under... Read More about Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies.

Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS) (2015)
Journal Article
Mamas, & Nolan. (2015). Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS). American Heart Journal, 164-172. https://doi.org/10.1016/j.ahj.2015.04.018

Background Gender is a strong predictor of periprocedural major bleeding complications after percutaneous coronary intervention (PCI). The access site represents an important site of such bleeding complications, which has driven adoption of the tran... Read More about Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS).

Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). (2015)
Journal Article
Mamas. (2015). Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). American Journal of Cardiology, 364-371. https://doi.org/10.1016/j.amjcard.2015.04.047

Influenza, influenza-like symptoms and their association with cardiovascular risks: a systematic review and meta-analysis of observational studies (2015)
Journal Article
Kwok, C. S., Aslam, S., Kontopantelis, E., Myint, P. K., Zaman, M. J. S., Buchan, I., …Mamas, M. A. (2015). Influenza, influenza-like symptoms and their association with cardiovascular risks: a systematic review and meta-analysis of observational studies. International Journal of Clinical Practice, 69(9), 928-937. https://doi.org/10.1111/ijcp.12646

Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT (2015)
Journal Article
Mamas. (2015). Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT. European Heart Journal - Cardiovascular Imaging, 521 - 530. https://doi.org/10.1093/ehjci/jeu295

AIMS: To examine the utility of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in the early diagnosis of cardiac implantable electronic device (CIED) generator pocket infection. METHODS AND RESULTS: A tot... Read More about Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT.

Incidence and mechanisms of longitudinal stent deformation associated with Biomatrix, Resolute, Element, and Xience stents: Angiographic and case‐by‐case review of 1,800 PCIs (2015)
Journal Article
Arnous, S., Shakhshir, N., Wiper, A., Ordoubadi, F., Williams, P., Clarke, B., …Fraser, D. (2015). Incidence and mechanisms of longitudinal stent deformation associated with Biomatrix, Resolute, Element, and Xience stents: Angiographic and case‐by‐case review of 1,800 PCIs. Catheterization and Cardiovascular Interventions, 86(6), 1002-1011. https://doi.org/10.1002/ccd.25790

Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12 (2015)
Journal Article
Shing Kwok, C., Kontopantelis, E., Myint, P. K., Zaman, A., Berry, C., Keavney, B., …Mamas, M. (2015). Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12. European Heart Journal, 36(25), 1618 -1628. https://doi.org/10.1093/eurheartj/ehv113

AIMS: This study aims to evaluate temporal changes in stroke complications and their association with mortality and MACE outcomes in a national cohort of patients undergoing percutaneous coronary interventions (PCIs) in England and Wales. METHODS AND... Read More about Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12.

Access and Non–Access Site Bleeding After Percutaneous Coronary Intervention and Risk of Subsequent Mortality and Major Adverse Cardiovascular Events: Systematic Review and Meta-Analysis (2015)
Journal Article
Kwok, C. S., Khan, M. A., Rao, S. V., Kinnaird, T., Sperrin, M., Buchan, I., …Mamas, M. A. (2015). Access and Non–Access Site Bleeding After Percutaneous Coronary Intervention and Risk of Subsequent Mortality and Major Adverse Cardiovascular Events: Systematic Review and Meta-Analysis. Circulation: Cardiovascular Interventions, 8(4), https://doi.org/10.1161/circinterventions.114.001645

Background— The prognostic impact of site-specific major bleeding complications after percutaneous coronary intervention (PCI) has yielded conflicting data. The aim of this study is to provide an overview of site-specific major bleeding events in co... Read More about Access and Non–Access Site Bleeding After Percutaneous Coronary Intervention and Risk of Subsequent Mortality and Major Adverse Cardiovascular Events: Systematic Review and Meta-Analysis.

Impact of age on access site‐related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society (2015)
Journal Article
Anderson, S. G., Ratib, K., Myint, P. K., Keavney, B., Kwok, C. S., Zaman, A., …Mamas, M. A. (2015). Impact of age on access site‐related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society. Catheterization and Cardiovascular Interventions, 86(6), 965-972. https://doi.org/10.1002/ccd.25896

We investigate adoption of the TRA in different age groups and study the relationship between age and access site related outcomes in a national cohort of patients undergoing PCI in the UK. Previous studies have reported conflicting data on radial ac... Read More about Impact of age on access site‐related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society.

Cardiac resynchronisation therapy is not associated with a reduction in mortality or heart failure hospitalisation in patients with non-left bundle branch block QRS morphology: meta-analysis of randomised controlled trials (2015)
Journal Article
Cunnington, C., Kwok, C. S., Satchithananda, D. K., Patwala, A., Khan, M. A., Zaidi, A., …Mamas, M. A. (2015). Cardiac resynchronisation therapy is not associated with a reduction in mortality or heart failure hospitalisation in patients with non-left bundle branch block QRS morphology: meta-analysis of randomised controlled trials. Heart, 101(18), 1456-1462. https://doi.org/10.1136/heartjnl-2014-306811

Access Site Practice and Procedural Outcomes in Relation to Clinical Presentation in 439,947 Patients Undergoing Percutaneous Coronary Intervention in the United Kingdom (2015)
Journal Article
Ratib, K., Mamas, M. A., Anderson, S. G., Bhatia, G., Routledge, H., De Belder, M., …Nolan, J. (2015). Access Site Practice and Procedural Outcomes in Relation to Clinical Presentation in 439,947 Patients Undergoing Percutaneous Coronary Intervention in the United Kingdom. JACC: Cardiovascular Interventions, 8(1), 20-29. https://doi.org/10.1016/j.jcin.2014.06.026

Objectives This study sought to determine the relationships among access site practice, clinical presentation, and procedural outcomes in a large patient population. Background Transradial access (TRA) has been associated with improved patient o... Read More about Access Site Practice and Procedural Outcomes in Relation to Clinical Presentation in 439,947 Patients Undergoing Percutaneous Coronary Intervention in the United Kingdom.